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Submissions from 2022

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A homozygous MED11 C-terminal variant causes a lethal neurodegenerative disease, Elisa Calì, Sheng-Jia Lin, Clarissa Rocca, Yavuz Sahin, Aisha Al Shamsi, Salima El Chehadeh, Myriam Chaabouni, SYNaPS Study Group, Shahnaz Ibrahim, and Salman Kirmani

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Spectrum of common pediatric neurological disorders: A cross-sectional study from three tertiary care centres across Pakistan, Prem Chand, Shahnaz Ibrahim, Khairunnisa Mukhtiar, Safia Awan, Durray Shahwar Abid Khan, Asna Sulaiman, Sajid Muhammad, Zahra Ali Padhani, Jai K. Das, and Mohammad Wasay

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Physician's attitudes on pulmonary rehabilitation following COVID-19: A brief perspective from a developing country, Ivan Cherrez-Ojeda, Emanuel Vanegas, Miguel Felix, María José Farfán Bajaña, Azza Sarfraz, Zouina Sarfraz, Genesis Camacho, Alanna Barrios-Ruiz, and Jack Michel

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Childhood mortality during and after acute illness in Africa and south Asia: A prospective cohort study, Childhood Acute Illness and Nutrition (CHAIN) Network, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahid, Ali Fazal Khan, Ali Faisal Saleem, Benson O. Singa, Blaise Siezanga Gnoumou, Caroline Tigoi, Syed Asad Ali, and Zaubina Kazi

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Performance of machine learning classifiers in classifying stunting among under-five children in Zambia, Obvious Nchimunya Chilyabanyama, Roma Chilengi, Roma Chilengi, Michelo Simuyandi, Caroline C. Chisenga, Masuzyo Chirwa, Kalongo Hamusonde, Rakesh Kumar Saroj, Najeeha Talat Iqbal, and Innocent Ngaruye

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Associations between eight earth observation-derived climate variables and enteropathogen infection: An independent participant data meta-analysis of surveillance studies with broad spectrum nucleic acid diagnostics, Josh M. Colston, Benjamin F. Zaithcik, Hamada S. Badr, Eleanor Burnett, Syed Asad Ali, Ajit Rayamajhi, Syed M. Satter, Daniel Eibach, Ralf Krumkamp, M Imran Nisar, Anita K. M. Zaidi, and Zulfiqar Ahmed Bhutta

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Risk factors for community-acquired bacterial infection among young infants in South Asia: A longitudinal cohort study with nested case–control analysis, Nicholas E. Connor, Mohammad Shahidul Islam, Luke C. Mullany, Nong Shang, Zulfiqar Ahmed Bhutta, Anita K. M. Zaidi, Sajid Bashir Soofi, Muhammad Imran Nisar, Pinaki Panigrahi, and Kalpana Panigrahi

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Alleviating hidden hunger: An infallible bridge to improved health and nutrition, Jai K. Das and Zahra Ali Padhani

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Risk of obstructive sleep apnea and traffic accidents among male bus drivers in Ecuador: Is there a significant relationship?, Miguel Felix, María Belén Intriago Alvarez, Emanuel Vanegas, María José Farfán Bajaña, Zouina Sarfraz, Azza Sarfraz, Jack Michel, and Ivan Cherrez-Ojeda

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Women's health: Optimal nutrition throughout the lifecycle, Edith J M Feskens, Regan Bailey, Zulfiqar Ahmed Bhutta, Hans-Konrad Biesalski, Heather Eicher-Miller, Klaus Krämer, Wen-Harn Pan, and James C. Griffiths

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Newborn weight change and predictors of underweight in the neonatal period in Guinea-Bissau, Nepal, Pakistan and Uganda, Valerie J. Flaherman, Amy S. Ginsburg, Muhammad Imran Nisar, Muddassir Altaf, Khushboo Liaquat, Benazir Baloch, Najeeb Rehman, Yasir Shafiq, Shabina Ariff, and Fyezah Jehan

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Prevalence of hearing loss in children living in low- and middle-income countries over the last 10 years: A systematic review, Hillary V. Ganek, Ada Madubueze, Catherine E. Merritt, and Zulfiqar Ahmed Bhutta

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Effects of prenatal exposure to maternal COVID-19 and perinatal care on neonatal outcome: results from the INTERCOVID Multinational Cohort Study, Francesca Giuliani, Daniel Oros, Robert B. Gunier, Sonia Deantoni, Stephen Rauch, Roberto Casale, Ricardo Nieto, Enrico Bertino, Albertina Rego, Camilla Menis, and Shabina Ariff

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Burden, clinical characteristics, risk factors, and seasonality of adenovirus 40/41 diarrhea in children in eight low-resource settings, Godfrey Guga, Sarah Elwood, Caroline Kimathi, Gagandeep Kang, Margaret N. Kosek, Aldo A M Lima, Pascal O. Bessong, Amidou Samie, Najeeha Talat Iqbal, and Zulfiqar Ahmed Bhutta

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Measuring contraceptive method mix, prevalence, and demand satisfied by age and marital status in 204 countries and territories, 1970-2019: A systematic analysis for the Global Burden of Disease Study 2019, Annie Haakenstad, Olivia Angelino, Caleb M S Irvine, Zulfiqar Ahmed Bhutta, Kelly Bienhoff, Corinne Bintz, Kate Causey, M Ashworth Dirac, Nancy Fullman, and Emmanuela Gakidou

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Effect of bovine lactoferrin on seroconversion following polio vaccine administration in children: Protocol for a double-blinded randomised controlled trial, Atif Habib, Sidrah Nausheen, Shanila Nooruddin, Tooba Javed, Tariq Samejo, Amjad Hussain, Suneeta Namdave, Sehrish Amirali, Muhammad Umer, and Lumaan Sheikh

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Health workers' experience of a digital health intervention implemented in peri-urban communities in Karachi, Pakistan, Kaniz Amna Haider, Omar Gulam, Rehan Adamjee, Benazir Baloch, and Zahra Hoodbhoy

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Diagnostic accuracy of various immunochromatographic tests for NS1 antigen and IgM antibodies detection in acute dengue virus infection, Mughees Haider, Saira Yousaf, Asifa Zaib, Azza Sarfraz, Zouina Sarfraz, and Ivan Cherrez-Ojeda

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Mental health and positive development prevention interventions: Overview of systematic reviews, Leila Harrison, Naeha Sharma, Omar Irfan, Michele Zaman, Tyler Vaivada, and Zulfiqar Ahmed Bhutta

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A case report on fibular aplasia, tibial campomelia, oligosyndactyly syndrome variant in a male infant, Hina Mumtaz Hashmi, Nazia Shamim, Vinod Kumar, Adnan Mirza, Salman Kirmani, Babar Irfan, and Hania Hasan

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Routine immunization coverage and immunization card retention in Pakistan: Results from a cross-sectional national survey, Imtiaz Hussain, Ahmad Khan, Dale A. Rhoda, Imran Ahmed, Muhammad Umer, Uzair Ansari, Muhammad Akram Shah, Soofia Yunus, Sajid Bashir Soofi, and Zulfiqar Ahmed Bhutta

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Practical approaches to improve vancomycin-related patient outcomes in pediatrics- an alternative strategy when AUC/MIC is not feasible, Kashif Hussain, Muhammad Sohail Salat, Shahzad Rauf, Manoj Rathi, Midhat Khan, Fizzah Naz, Wasif Ahmed Khan, Rahila Ikram, and Gul Ambreen

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Optimal iron content in ready-to-use therapeutic foods for the treatment of severe acute malnutrition in the community settings: A protocol for the systematic review and meta-analysis, Aamer Imdad, Melissa François, Fanny F. Chen, Abigail Smith, Olivia Tsistinas, Emily Tanner Smith, Jai K. Das, and Zulfiqar Ahmed Bhutta

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Enteroinvasive Escherichia Coli O96: H19 is an emergent biofilm-forming pathogen, Junaid Iqbal, Niharika Malviya, Jennifer A. Gaddy, Chengxian Zhang, Andrew J. Seier, Kathryn P. Haley, Ryan S. Doster, Ana E. Farfán-García, and Oscar G. Gómez-Duarte

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Zinc supplementation and the prevention and treatment of sepsis in young infants: A systematic review and meta-analysis, Omar Irfan, Robert E. Black, Zohra S. Lassi, and Zulfiqar Ahmed Bhutta

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Early postoperative arrhythmias after pediatric congenital heart disease surgery: A 5-year audit from a lower- to middle-income country, Sidra Ishaque, Saleem Akhtar, Asma Akbar Ladak, Russell Seth Martins, Muhammad Kamran Younis Memon, Alisha Raza Kazmi, Fatima Mahmood, and Anwar Ul Haque

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Community-based asthma assessment in young children: Adaptations for a multicentre longitudinal study in South Asia, Mohammad Shahidul Islam, Samin Huq, Steven Cunningham, Jurgen Schwarze, ASMD Ashraful Islam, Mashal Amin, Farrukh Raza, Benazir Baloch, Muhammad Imran Nisar, and Sajid Bashir Soofi

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Prevention and management of high-burden noncommunicable diseases in school-age children: A systematic review, Reena P. Jain, Daina Als, Tyler Vaivada, and Zulfiqar Ahmed Bhutta

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Frequency of use and preferences for information and communication technologies in patients with sleep apnea: A multicenter, multinational, observational cross-sectional survey study, Veronica R. Jaritos, Emanuel Vanegas, Juan Facundo Nogueira, Sebastian Leiva Agüero, Vanina Giovini, Jorge Rey de Castro, Yadira Rodríguez Reyes, José Luis Carrillo Alduenda, Pammela Torres Gittaim, Zaira Romero, and Azza Sarfraz

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The WHO global tuberculosis 2021 report - not so good news and turning the tide back to end TB, Chakaya Jeremiah, Eskild Petersen, Rebecca Nantanda, Brenda N. Mungai, Giovanni Battista Migliori, Farhana Amanullah, Patrick Lungu, Francine Ntoumi, and Nagalingeswaran Kumarasamy

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Compounding inequalities: Adolescent psychosocial wellbeing and resilience among refugee and host communities in jordan during the COVID-19 pandemic, Nicola Jones, Sarah Baird, Bassam Abu Hamad, Zulfiqar Ahmed Bhutta, Erin Oakley, Manisha Shah, Jude Sajdi, and Kathryn M. Yount

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COVID-19, nutrition, and gender: An evidence-informed approach to gender-responsive policies and programs, Anna Kalbarczyk, Noora-Lisa Aberman, Bregje S M van Asperen, Rosemary Morgan, Zulfiqar Ahmed Bhutta, Bianca Carducci, Rebecca Heidkamp, Saskia Osendarp, Neha Kumar, and Anna Lartey

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Exploring terminology for puerperal sepsis and its symptoms in urban Karachi, Pakistan to improve communication, care-seeking, and illness recognition, Anna Kalbarczyk, Fatima Mir, Shabina Ariff, Aspara Ali, Abdul Momin Kazi, Gurpreet Kaur, Farheen Yousuf, Farzeen Hirani, Shazia Sultana, Linda A. Bartlett, Amnesty E. Lefevre, and Sajid Bashir Soofi

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Acute stress in parents of patients admitted to the pediatric intensive care unit: A two-center cross-sectional observational study, Daniel Kaplan, Mekela Whyte Nesfield, Peter S. Eldridge, WIlliam Cuddy, Nadia Ansari, Pamela Siller, and Simon Li

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Malaria reduction drove childhood stunting decline in Uganda: A mixed-methods country case study, Emily C. Keats, Richard B. Kajjura, Anushka Ataullahjan, Muhammad Islam, Breagh Cheng, Ahalya Somaskandan, Kimberly D. Charbonneau, Erica Confreda, Rachel Jardine, and Zulfiqar A. Bhutta

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Knowledge and Practices on the Prevention and management of diarrhea in children under-2 years among women dwelling in urban slums of Karachi, Pakistan, Asif Khaliq, Amreen 1, Nazia Jameel, and Stefanie J. Krauth

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Burden and risk factors for antenatal depression and its effect on preterm birth in South Asia: A population-based cohort study, Rasheda Khanam, Jennifer Applegate, Muhammad Imran Nisar, Arup Dutta, Sayedur Rahman, Ambreen Nizar, Said Mohammed Ali, Farzana Begum, Usma Mehmood, and Sajid Muhammad

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Nutritional status and dietary intake of school-age children and early adolescents: Systematic review in a developing country and lessons for the global perspective, Durray Shahwar Abid Khan, Jai K. Das, Shagufta Zareen, Zohra S. Lassi, Afsah Salman, Muhammad Raashid, Aftab A. Dero, Aijaz Khanzada, and Zulfiqar Ahmed Bhutta

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Interventions for high-burden infectious diseases in children and adolescents: A meta-analysis, Durray Shahwar Abid Khan, Rabia Naseem, Rehana Salam, Zohra Lassi, Jai K. Das, and Zulfiqar Ahmed Bhutta

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Multiplex PCR assay to detect high risk lineages of Salmonella Typhi and Paratyphi A, Fahad Khokhar, Derek Pickard, Zoe Dyson, Junaid Iqbal, Agila Pragasam, Jobin Jacob John, Balaji Veeraraghavan, Farah Qamar, Gordon Dougan, and Hilary MacQueen

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Measurement of sound levels in a neonatal intensive care unit of a tertiary care hospital, Karachi, Pakistan, Saleema Khowaja, Shabina Ariff, Laila Ladak, Zainab Manan, and Tazeen S. Ali

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Improving health and social systems for all children in LMICs: Structural innovations to deliver high-quality services, Margaret E. Kruk, Todd P. Lewis, Catherine Arsenault, Zulfiqar Ahmed Bhutta, Grace Irimu, Joshua Jeong, Zohra S. Lassi, Susan M. Sawyer, Tyler Vaivada, and Peter Waiswa

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Relationship of caffeine regimen with osteopenia of prematurity in preterm neonates: A cohort retrospective study, Manoj Kumar, Amin Ali, Muhammad Azeem Khan, Sadia Sohail, Syed Muzaffar Saleem, Fizzah Naz, Wasif Ahmed Khan, Muhammad Sohail Salat, Kashif Hussain, and Gul Ambreen

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Etiology, sensitivity and resistance pattern of urinary tract infection among children (0 To 16 Years), Manoj Kumar, Warda Khalid, Amin Ali, Syed Khurram Sajid, Yumna Muhammad Aslam, and Ayaz Ur Rehman

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Towards standardised and valid anthropometric indicators of nutritional status in middle childhood and adolescence, Natasha Lelijveld, Rukundo K. Benedict, Stephanie V. Wrottesley, Zulfiqar Ahmed Bhutta, Elaine Borghi, Tim J. Cole, Trevor Croft, Edward A. Frongillo, Chika Hayashi, and Sorrel Namaste

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Oral amoxicillin plus gentamicin regimens may be superior to the procaine-penicillin plus gentamicin regimens for treatment of young infants with possible serious bacterial infection when referral is not feasible: Pooled analysis from three trials in Africa and Asia, Adrien Lokangaka Longombe, Adejumoke Idowu Ayede, Irene Marete, Fatima Mir, Clara Ladi Ejembi, Mohammod Shahidullah, Ebunoluwa A. Adejuyigbe, Robinson D. Wammanda, Antoinette Tshefu, and Anita K. M. Zaidi

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The promise of telemedicine in Pakistan: A systematic review, Syed Sarosh Mahdi, Raheel Allana, Gopi Battineni, Tamsal Khalid, Daniyal Agha, Mariam Khawaja, and Francesco Amenta

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Perspective on newborn screening (NBS): Evidence sharing on conditions to be included in NBS in Pakistan, Hafsa Majid, Lena Jafri, Sibtain Ahmed, Khadija Humayun, Salman Kirmani, Natasha Bahadur Ali, Bushra Moiz, Aysha Habib, and Bushra Afroze

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Anti-PD-1 immunotherapy - Pembrolizumab current clinical trials for advanced head and neck cancer: A mapping systematic study, Humayun Manzoor, Amina Rasheed, Farah Zeen, Azza Sarfraz, and Zouina Sarfraz

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Ventilator associated pneumonia in neonatal intensive care unit: Occurrence and risk factors, Fayaz Ahmed Memon, Javaid Iqbal, Faraz Hussain, Khalil Ahmad, Abdul Jabbar, and Shabina Ariff

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Wolcott-Rallison syndrome: A case series of three patients, Fozia Memon, Muzna Arif, Salman Kirmani, and Khadija N Humayun

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Epidemiological characteristics, treatment and its outcomes in children presenting with craniopharyngioma at a tertiary care center, Fozia Memon, Muzna Arif, Naureen Mushtaq, Salman Kirmani, and Khadija N Humayun

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Pregnancy outcomes of patients with ultrasound-indicated and history-indicated mcdonald cervical cerclage, Zaibunnisa Memon, Naureen Anjum, and Zahra Hoodbhoy

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Immunity to poliovirus in Afghanistan: A household sampling method for serological assessment based on geographical information systems, Amalia Mendes, Ari Whiteman, Benjamin Nygren, Brian Kaplan, Imtiaz Hussain, Sajid Bashir Soofi, Maureen Martinez, and Noha H. Farag

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Risk factors for acute respiratory infections in children between 0 and 23 months of age in a peri-urban district in Pakistan: A matched case–control study, Fatima Mir, Shabina Ariff, Maria Asif Bhura, Suhail Chanar, Aspara Ali, Muhammad Jawwad, A Hussain, Arjumand Rizvi, Muhammad Umer, Zahid Memon, Atif Habib, Sajid Bashir Soofi, and Zulfiqar Ahmed Bhutta

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Quality improvement initiative in paediatric echocardiography laboratory in a low- to middle-income country, Shazia Mohsin, Babar Hasan, Mishaal Ather, Salima Ashiqali, Nadeem Aslam, Farah Khalid, Zain Adil Shabbir, Shaan Adil Shabbir, and Devyani Chowdhury

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Ameliorative effects of half-dose saffron and chamomile combination on Psycho-endocrinological changes in a diabetic murine model, Saara Muddasir, Hamna Rafique, Asra Khan, Prashant Tikmani, Zehra Batool, Saiqa Tabassum, Fazal M. Arain, Salman Siddiqi, Faiq Amin, and Muhammad Wasim

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A systematic review of internet of things in clinical laboratories: Opportunities, advantages, and challenge, Tahir Munir, Muhammad Soomair Akbar, Sadia Ahmed, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz, Miguel Felix, and Ivan Cherrez-Ojeda

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Impact of interpregnancy intervals on perinatal and neonatal outcomes in a multiethnic Pakistani population, Khadija Murtaza, Zahra Saleem, Saliha Jabeen, A Khuzaim Alzahrani, Nadeem Kizilbash, Sajid Bashir Soofi, Haider Shirazi, Amanullah Yasin, and Sajid Malik

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Cost-effectiveness analysis of implementing an integrated neonatal care kit to reduce neonatal infection in rural Pakistan, Fiona Muttalib, Karen Chung, Lisa Grace Pell, Shabina Ariff, Sajid Soofi, Shaun K. Morris, and Beate Sander

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Interventions for neglected tropical diseases among children and adolescents: A meta-analysis, Fatima Abbas Naqvi, Jai K. Das, Rehana Salam, Syeda Fatima Raza, zohra lassi, and Zulfiqar Ahmed Bhutta

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Viral infections in Pakistan: Prevalence, factors affecting spread, and recommendations for control, Zehra Naseem, Maaha Ayub, Sharaf Ali Shah, Syed Asad Ali, and Syed Hani Abidi

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Anakinra treatment efficacy in reduction of inflammatory biomarkers in COVID-19 patients: A meta-analysis, Zunaira Naveed, Musharraf Sarwar, Zahid Ali, Danish Saeed, Khadija Choudhry, Azza Sarfraz, Zouina Sarfraz, Miguel Felix, and Ivan Cherrez-Ojeda

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The role of precision medicine in head and neck cancer: A systematic study of ongoing clinical trials, Periea Kiran Nazeer, Saima Shaheen, Kashmala Shafique, Azza Sarfraz, Shehar Bano, and Zouina Sarfraz

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CMV and EBV co-infection in HIV-infected children: Infection rates and analysis of differential expression of cytokines in HIV mono- and HIV-CMV-EBV co-infected groups, Fizza Nazim, Hammad Afzal Kayani, Aspara Ali Nathwani, Fatima Mir, and Syed Hani Abidi

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Neurodevelopment assessment of small for gestational age children in a community-based cohort from Pakistan, Sabahat Naz, Zahra Hoodbhoy, Ali Jaffar, Sidra Kaleem Jafri, Babar Hasan, Devyani Chowdhury, and Melissa Gladstone

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Serotype-specific effectiveness against pneumococcal carriage and serotype replacement after ten-valent pneumococcal conjugate vaccine (PCV10) introduction in Pakistan, Muhammad Imran Nisar, Fyezah Jehan, Shahira Shahid, Sheraz Ahmed, Sadia Shakoor, Furqan Kabir, Aneeta Hotwani, Sahrish Muneer, Farah Khalid, Sajid Muhammad, Asad Ali, and Najeeha Talat Iqbal

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Treatment outcomes and prognostic factors of childhood acute lymphoblastic leukemia in a low-middle income population: A multi-institutional report from Pakistan, Muhammad Imran Nisar, Shahira Shahid, Fatimah Yousuf, Laila Saleem Lakhani, Shamvil Ashraf, Uzma Imam, Junaid Zaheer, Asim Belgaumi, and Zehra Fadoo

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The Childhood Acute Illness and Nutrition (CHAIN) network nested case-cohort study protocol: A multi-omics approach to understanding mortality among children in sub-Saharan Africa and South Asia, James M. Njunge, Kirkby Tickell, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahi, Md Amran Gazi, Ali Faisal Saleem, Zaubina Kazi, Syed Ali, Caroline Tigoi, and Ezekiel Mupere

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Building knowledge, optimising physical and mental health and setting up healthier life trajectories in South African women ( Bukhali): A preconception randomised control trial part of the Healthy Life Trajectories Initiative (HeLTI), Shane A. Norris, Catherine E. Draper, Alessandra Prioreschi, C M Smuts, Lisa Jayne Ware, CindyLee Dennis, Philip Awadalla, D Bassani, Zulfiqar Ahmed Bhutta, and Laurent Briollais

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World tuberculosis day 2022: Aligning COVID-19 and tuberculosis innovations to save lives and to end tuberculosis, Francine Ntoumi, Jean B. Nachega, Eleni Aklillu, Jeremiah Chakaya, Irina Felker, Farhana Amanullah, Dorothy Yeboah-Manu, Kenneth G. Castro, and Alimuddin Zumla

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The unique relevance of executive functions and self-regulation behaviors for understanding early childhood experiences and preschoolers' outcomes in rural Pakistan, Jelena Obradović, Jenna E. Finch, Catie Connolly, Saima Siyal, and Aisha K. Yousafzai

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Digital interventions for universal health promotion in children and adolescents: A systematic review, Christina Oh, Bianca Carducci, Tyler Vaivada, and Zulfiqar Ahmed Bhutta

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Interventions to promote physical activity and healthy digital media use in children and adolescents: A systematic review, Christina Oh, Bianca Carducci, Tyler Vaivada, and Zulfiqar Ahmed Bhutta

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Diagnostic accuracy of artificial intelligence for detecting gastrointestinal luminal pathologies: A systematic review and meta-analysis, Om Parkash, Asra Tus Saleha Siddiqui, Uswa Jiwani, Fahad Rind, Zahra Ali Padhani, Arjumand Rizvi, Zahra Hoodbhoy, and Jai K. Das

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Pediatric critical care nursing research priorities in Asia: An eDelphi study, Pei-Fen Poh, Qian Wen Sng, Jos M. Latour, Linxi He, Mei Fung Fong, Jayashree Muralidharah, Qalab Abbas, Yujiro Matsuishi, and Jan Hau Lee

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Salmonellosis including enteric fever, Farah Qamar, Wajid Hussain, and Sonia Qureshi

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Implementation evaluation of a leadership development intervention for improved family experience in a private paediatric care hospital, Pakistan, Muneera A. Rasheed, Ayesha Hussain, Amin Hashwani, Johannes T. Kedzierski, and Babar S. Hasan

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Factors affecting accidental toxic ingestion among children younger than 5 years, Ambreen Raza, Mahnaz Hakeem, Hafsa Zaheer, Sana Samreen, Falak Naz, and Bushra Afroze

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Barriers and facilitators to exclusive breastfeeding in rural Pakistan: A qualitative exploratory study, Atif Riaz, Shelina Bhamani, Sheraz Ahmed, Fayyaz Umrani, Sadaf Jakhro, Abdul Khaliq Qureshi, and Syed Asad Ali

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Guidance relevant to the reporting of health equity in observational research: A scoping review protocol, Anita Rizvi, Daeria O. Lawson, Taryn Young, Omar Dewidar, Stuart Nicholls, Elie A. Akl, Julian Little, Olivia Magwood, Larissa Shamseer, and Zulfiqar Ahmed Bhutta

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Effects of delayed versus immediate umbilical cord clamping in reducing death or major disability at 2 years corrected age among very preterm infants (APTS): A multicentre, randomised clinical trial, Kristy P. Robledo, William O. Tarnow-Mordi, Ingrid Rieger, Preeti Suresh, Andrew Martin, Carbo Yeung, Alpana Ghadge, Lumaan Sheikh, Shabina Ariff, and Bakhtawar Muhammad Hanif Khowaja

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Frequency of bystander exposure to antibiotics for enteropathogenic bacteria among young children in low-resource settings, Elizabeth T. Rogawski McQuade, Stephanie A. Brennhofer, Sarah E. Elwood, Timothy L. McMurry, Joseph A. Lewnard, Estomih R. Mduma, Sanjaya Shrestha, Najeeha Talat Iqbal, Pascal O. Bessong, and Gagandeep Kang

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The epidemiology of sapovirus in the etiology, risk factors, and interactions of enteric infection and malnutrition and the consequences for child health and development study: Evidence of protection following natural infection, Saba Rouhani, Pablo Peñataro Yori, Maribel Paredes Olortegui, Aldo A. Lima, Tahmeed Ahmed, Estomih R. Mduma, Ajila George, Amidou Samie, Erling Svensen, and Adil Kalam

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Risk factors for acute diarrhoea in children between 0 and 23 months of age in a peri-urban district of Pakistan: A matched case-control study, Kamran Sadiq, Fatima Mir, Uswa Jiwani, Suhail Chanar, Apsara Ali Nathwani, Muhammad Jawwad, Amjad Hussain, Arjumand Rizvi, Shah Muhammad, and Muhammad Atif Habib

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Teaching clinical skills using online modality through modified peyton’s framework: An experience from a medical university in Pakistan, sana saeed, Urooj Kashif, Samar Zaki, Khalid Samad, Muhammad Zuhair Yusuf, Mahanoor Raza, Shahjahan Jabbar, and Unab I. Khan

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An epidemiological, strategic and response analysis of the COVID-19 pandemic in South Asia: A population-based observational study, Hafiz Muhammad Salman, Javaria Syed, Atif Riaz, Zouina Sarfraz, Azza Sarfraz, Syed Hashim Abbas Ali Bokhari, and Ivan Cherrez Ojeda

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Leveraging clinical digitized data to understand temporal characteristics and outcomes of acute myocardial infarctions at a tertiary care medical centre in Pakistan from 1988-2018 - Methods and results, Zainab Samad, Ali Aahil Noorali, Awais Farhad, Safia Awan, Nada Qaiser Qureshi, Mushyada Ali, Laiba Masood, Ghurfan Adnan, Zulfiqar Ahmed Bhutta, and Javed Tai

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Factors associated with parental refusal for lumber puncture among children and adolescent: A cross sectional survey at a tertiary care hospital, Sana Samreen, Mahnaz Hakeem, Hafsa Zaheer, Ambreen Raza, and Abdul Gaffar Billoo

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Impact of biosecurity measures, social pressure and bullying on attitudes, perceptions, and job satisfaction levels among healthcare workers during the COVID-19 pandemic: A cross-sectional survey, Azza Sarfraz, Zouina Sarfraz, Genesis Camacho-Leon, Geovanny Efraín Alvarado-Villa, Derly Madeleiny Andrade-Molina, Juan Carlos Fernandez-Cadena, Arjola Agolli, Zeynep Yukselen, Miguel Felix, and Juan Carlos Gallardo Bastidas

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Menstrual irregularities following COVID-19 vaccination: A global cross-sectional survey, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz, Zainab Nadeem, Miguel Felix, and Ivan Cherrez-Ojeda

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Gender-based violence in Pakistan and public health measures: A call to action, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz, and Zul Qarnain

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Industry 4.0 technologies for the manufacturing and distribution of COVID-19 vaccines, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz, Aminah Abdul Razzack, Shehar Bano, Sarabjot Singh Makkar, Sindhu Thevuthasan, Trissa Paul, Muhammad Khawar Sana, and Nishwa Azeem

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Social contributors for the rise of COVID-19 infections in South Asia: A large cross-sectional survey, Zouina Sarfraz, Azza Sarfraz, Muzna Sarfraz, Nishwa Azeem, Namrata Hange, Miguel Felix, and Ivan Cherrez-Ojeda

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Contact dermatitis due to personal protective equipment use and hygiene practices during the COVID-19 pandemic: A systematic review of case reports, Zouina Sarfraz, Azza Sarfraz, Muzna Sarfraz, Miguel Felix, Jonathan A. Bernstein, Luz Fonacier, and Ivan Cherrez-Ojeda

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Machine learning prediction of gestational age from metabolic screening markers resistant to ambient temperature transportation: Facilitating use of this technology in low resource settings of South Asia and East Africa, Sunil Sazawal, Sayan Das, Kelli K. Ryckman, Rasheda Khanam, Saikat Deb, Elizabeth A. Jasper, Sayedur Rahman, Usma Mehmood, Arup Dutta, Nabidul Haque Chowdhury, Amina Barkat, Farah Khalid, Muhammad Ilyas, Ambreen Nizar, and Fyezah Jehan

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Pneumococcal carriage in infants post-PCV10 introduction in Pakistan: Results from serial cross-sectional surveys, Shahira Shahid, Amala Khan, Muhammad Imran Nisar, Farah Khalid, Muhammad Farrukh Qazi, Sheraz Ahmed, Furqan Kabir, Aneeta Hotwani, Sahrish Muneer, Syed Asad Ali, Anita K. M. Zaidi, and Fyezah Jehan

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Updates in pediatric tuberculosis in international settings, Sadia Shakoor and Fatima Mir

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Delivery strategies supporting school-age child health: A systematic review, Naeha Sharma, Ayesha Asaf, Tyler Vaivada, and Zulfiqar Ahmed Bhutta

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Interventions to improve immunization coverage among children and adolescents: A meta-analysis, Faareha A. Siddiqui, Zahra Ali Padhani, Rehana Salam, Razia Aliani, Zohra Lassi, Jai K. Das, and Zulfiqar Ahmed Bhutta