Welcome to the department of Haematology Oncology. Our department is comprised of multiple sub-specialties with diverse faculty trained both locally and internationally, in the fields of haematology (treatment of blood disorders), oncology (treatment of cancers of solid organs), radiation therapy (treatment of various cancers using therapeutic forms of radiation), palliative care (improvement of the quality of life through symptom management, survivorship, home health services for cancer patients and multi-system holistic care). ​Our faculty, fellows and staff are committed to ensuring top notch patient-centered services and excellence in education.

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Submissions from 2002

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Treatment with ibritumomab tiuxetan radioimmunotherapy in patients with rituximab-refractory follicular non-Hodgkin’s lymphoma, Thomas Witzig, Ian Flinn, Leo Gordon, Christos Emmanouilides, Myron Czuczman, Mansoor Saleh, Larry Cripe, Gregory Wiseman, Teresa Olejnik, and Pratik Multani

Submissions from 2001

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Pivotal study of iodine I 131 tositumomab for chemotherapy-refractory low-grade or transformed low-grade B-cell non-Hodgkin’s lymphomas, Mark Kaminski, Andrew Zelenetz, Oliver Press, Mansoor Saleh, John Leonard, Louis Fehrenbacher, Andrew Lister, and Julie Vose

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A pilot trial of vitaxin, A humanized anti-vitronectin receptor (anti αvβ3) antibody in patients with metastatic cancer, James Posey, M B. Khazaeli, Alma DelGrosso, Mansoor Saleh, Chin Yu Lin, William Huse, and Albert LoBuglio

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Phase I study of anti–epidermal growth factor receptor antibody cetuximab in combination with radiation therapy in patients with advanced head and neck cancer, Francisco Robert, Mark Ezekiel, Sharon Spencer, Ruby Meredith, James Bonner, Mansoor Saleh, Delicia Carey, Albert LoBuglio, and Richard Wheeler

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Clearing of cells bearing the bcl-2 [t(14;18)] translocation from blood and marrow of patients treated with rituximab alone or in combination with CHOP chemotherapy, Mansoor Saleh, Grillo López, John McLaughlin, Catherine White, Leo Gordon, and David Maloney

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Zevalin radioimmunotherapy offers safe and effective therapy for relapsed or refractory, B cell non-Hodgkin's lymphoma (nhl), Mansoor Saleh, Christine White, Thomas Witzig, Leo Gordon, Greg Wiseman, Christos Emmanouilides, James Murray, Andrew Lister, Robert Landin, and Pratik Multani

Submissions from 2000

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Enhanced apoptosis with combination C225/radiation treatment serves as the impetus for clinical investigation in head and neck cancers, James Bonner, Kevin Raisch, Heath Trummell, Francisco Robert, Robert Meredith, Sharon Spencer, Donald Buchsbaum, Mansoor Saleh, and Mark Stackhouse

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Phase I trial of the anti-Lewis Y drug immunoconjugate BR96-doxorubicin in patients with lewis Y-expressing epithelial tumors, Mansoor Saleh, Sam Sugarman, John Murray, Jamie Ostroff, David Healey, Dan Jones, Daniel Craig, and Carmen Lebherz

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Phase I trial of the anti–Lewis Y drug immunoconjugate BR96-doxorubicin in patients with Lewis Y–expressing epithelial tumors, Mansoor Saleh, Steve Sugarman, James Murray, Joy Ostroff, Diane Healey, Dennie Jones, Carol Daniel, and Donna LeBherz

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Multicenter phase II study of iodine-131 tositumomab for chemotherapy-relapsed/refractory low-grade and transformed low-grade B-cell non-Hodgkin’s lymphomas, Julie Vose, Richard Wahl, Mansoor Saleh, Ama Rohatiner, Susan Knox, John Radford, Andrew Zelenetz, and George Tidmarsh

Submissions from 1999

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Rituximab for the treatment of AIDS-associated non-Hodgkin's lymphoma (AIDS-NHL) abstract 121, Jeffrey Barrett, Carol Linn, and Mansoor Saleh

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Phase I trial of a recombinant vaccinia virus encoding carcinoembryonic antigen in metastatic adenocarcinoma: comparison of intradermal versus subcutaneous administration, Robert Conry, Muhamad Khazaeli, Mansoor Saleh, Karen Allen, Daunte Barlow, Susan Moore, Dayle Craig, Ramin Arani, Jeffrey Schlom, and Albert LoBuglio

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Treatment of Patients With Low-Grade B-Cell Lymphoma With the Combination of Chimeric Anti-CD20 Monoclonal Antibody and CHOP Chemotherapy, Myron Czuczman, Angel Grillo-López, Catherine White, Mansoor Saleh, Leo Gordon, Albert LoBuglio, Cynthia Jonas, David Klippenstein, and Bernard Dallaire

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NCCN practice guidelines for Hodgkin's disease, Richard Hoppe, Richard Abrams, Steven Bernstein, Paul Bierman, Clara Bloomfield, James Cox, Leo Gordon, Sandra Horning, and Mark Kaminski

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Combined modality therapy of A431 human epidermoid cancer using Anti-EGFr antibody C225 and radiation, Mansoor Saleh, Kevin Raisch, Murray Stackhouse, William Grizzle, James Bonner, Matthew Mayo, Hyung-Gyoon Kim, Ruby Meredith, and Richard Wheeler

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Randomized phase II study of BR96-doxorubicin conjugate in patients with metastatic breast cancer, Anthony Tolcher, Steven Sugarman, Mansoor Saleh, Karen Gelmon, Roger Cohen, Claudine Isaacs, Leslie Young, Diane Healey, and Nicole Onetto

Submissions from 1998

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Diphtheria toxin fusion proteins, Frank Foss, Mansoor Saleh, James Krueger, John Nichols, and John Murphy

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Phase I trial of a ligand fusion-protein (DAB389IL-2) in lymphomas expressing the receptor for Interkeukin-2, Charles LeMaistre, Mansoor Saleh, Timothy Kuzel, Francine Foss, Leonidas Platanias, Gary Schwartz, Mark Ratain, and Alain Rook

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Phase I study of anti-epidermal growth factor receptor (anti-EGFR) antibody C225 in combination with irradiation in patients with advanced squamous cell carcinoma of the head and neck (SCCHN)., Mansoor Saleh, Michael Ezekiel, Francis Robert, Robert Meredith, Susan Spencer, James Newsome, Gregory Peters, and Albert LoBuglio

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Antitumor activity of DAB389 IL-2 fusion toxin in mycosis fungoides, Mansoor Saleh, C. F. LeMaistre, Timothy Kuzel, Francine Foss, Leonidas Platanias, Gary Schwartz, Mark Ratain, Alain Rook, and Cesar Freytes

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Immunologic response to the dual murine anti-Id vaccine Melimmune-1 and Melimmune-2 in patients with high-risk melanoma without evidence of systemic disease, Mansoor Saleh, Michael Pride, Alan Solinger, Matthew Mayo, Albert LoBuglio, and James Murray

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Chimeric antibodies with specificity for tumor antigens: demonstration of in situ localization to tumors after antibody therapy, Mansoor Saleh, Arabella Tilden, Ruby Meredith, Albert Lobuglio, and William Grizzle

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First line chemotherapy with paclitaxel (P) and mitoxantrone (M) metastatic breast cancer (MBC). A phase II study, Dimitrios Tsavdaridis, Andreas Athanassiadis, Penelope Kourtidou, Antonios Liaros, Anastasios Apostolidis, Georgios Harmouziadis, and Mansoor Saleh

Submissions from 1997

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A novel gene therapy strategy for elimination of prostate carcinoma cells from human bone marrow., Myunghee Kim, Marci Wright, Jessy Deshane, Mary Ann Accavitti, Arabella Tilden, William Vaughan, Mansoor Saleh, Matthew Karabasi, Miriam Rogers, and Richard Hockett

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Correlation of toxicity with treatment parameters for 131I-CC49 radioimmunotherapy in three phase II clinical trials, Tiepu Liu, Ruby Meredith, Richard Wheeler, Mansoor Saleh, Walter Plott, Jeffrey Schlom, and Albert Lobuglio

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Interleukin-2 fusion protein: an investigational therapy for interleukin-2 receptor expressing malignancies, Jean Nichols, Foss Francine, Kuzel Timothy, LeMaistre Charles Fred, Platanias Leonidas, Ratain Mark, Rook Alain, Mansoor Saleh, and Schwartz Gary

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503 Phase I radioimmunotherapy (RIT) study of 90Y-CC49 monoclonal antibody (MAb) therapy in patients with advanced non-small cell lung cancer (NSCLC), Francisco Robert, Ruby Meredith, Michael Khazaeli, Charles Russell, William Grizzle, John Newsome, and Mansoor Saleh

Submissions from 1996

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Phase Ia/Ib trial of anti-GD2 chimeric monoclonal antibody 14.18 (ch l4.18) and recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) in metastatic melanoma, James Murray, Eugenie Kleinerman, Shu-Fang Jia, Michael Rosenblum, Omar Eton, Antonio Buzaid, Sewa Legha, Merrick Ross, Lora Thompson, and Mansoor Saleh

Submissions from 1995

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Phase I trial of an anti-CD19 deglycosylated ricin a chain immunotoxin in non-hodgkin's lymphoma effect of an intensive schedule of administration, Conry Robert, Khazaeli Michael, Mansoor Saleh, Ghetie Victor, Vitetta Ellen, Liu Tiepu, and Logbulio Albert

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Phase II trial of murine monoclonal antibody D612 combined with recombinant human monocyte colony-stimulating factor (rhM-CSF) in patients with metastatic gastrointestinal cancer, Mansoor Saleh, Michael Khazaeli, Richard Wheeler, Pat Bucy, Tiepe Liu, Michael Everson, David Mun, and Jeff Schlom

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Effect of alcohol on the postnatal development of white matter of the cerebellum of the rat, Mansoor Saleh, M A. Saleh, Desouky Saadia, and Entesar Saber

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CD16+ monocytes in patients with cancer: spontaneous elevation and pharmacologic induction by recombinant human macrophage colony- stimulating factor, Mansoor Saleh, Goldman Samuel, LoBuglio Albert, Beall Arthur, Sabio Hernan, McCord Melissa, Minasian Lori, Alpaugh Katherine, Weiner Louis, and Munn David

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Effect of alcohol on the postnatal development of cerebellar cortex in rat II: ultrastructural study, Mansoor Saleh, Saadia Sayed, and Entesar Saber

Submissions from 1994

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Ocular toxicity of recombinant melanoma vaccine (Melimmune), Swanson Mark and Mansoor Saleh

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Clinical experience with murine, human and genetically engineered monoclonal antibodies, Mansoor Saleh, R M. Conry, and A F. Lobuglio

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Phase Ib study of melimmune (bivalent) anti-Id antibodies (Ab) in patients with resected melanoma., Mansoor Saleh, Lalisan D, Gibson M, Merritt J, Grillo Lopez A, and Lobuglio A

Submissions from 1993

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Assessment of quality of life in patients receiving monoclonal antibody therapy for cancer., Trammell L, Edmonds K, Wright P, and Mansoor Saleh

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A phase I clinical trial of murine monoclonal antibody D612 in patients with metastatic gastrointestinal cancer., Mansoor Saleh, M B. Khazaeli, William Grizzle, Richard Wheeler, Sharon Lawson, Tiepe Liu, Charles Russell, Ruby Meredith, Jeffrey Schlom, and Albert Lobuglio

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Effect of alcohol on the postnatal development of cerebellar cortex in rat guste 1-histological and morphometric studies., Mansoor Saleh, M N. Saleh, M A. Desouky, Saadia Sayed, and Entesar Saber

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Generation of a human anti-idiotypic antibody that mimics the GD2 antigen., Mansoor Saleh, J D. Stapleton, M B. Khazaeli, and A F. Lobuglio

Submissions from 1992

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Frequent anti-V-region immune response to mouse B72. 3 monoclonal antibody, M B. Khazaeli, Mansoor Saleh, Tiepu Liu, Paul Kaladas, Steve Gilman, and Albert LoBuglio

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Monoclonal antibody therapy of cancer, Albert LoBuglio and Mansoor Saleh

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Phase I trial of iodine-131-chimeric B72. 3 (human IgG4) in metastatic colorectal cancer, Ruby F. Meredith, M B. Khazaeli, Walter Plott, Mansoor Saleh, Tiepu Liu, Laquetta Allen, Charles Russell, and Roger Orr

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Selection of platelets for refractory patients by HLA matching and prospective cross-matching., G Moroff, G Garratty, J M. Heal, B R. MacPherson, D Stroncek, S T. Huang, Winston Ho, and Mansoor Saleh

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Phase I trial of the chimeric anti-GD2 monoclonal antibody ch14.18 in patients with malignant melanoma, Mansoor Saleh, Khazaeli M. B, Wheeler Richard, Allen Laquetta, Tilden Arabella, Grizzle William, Reisfeld Ralph, Yu Alice, and Gillies Stephen

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Phase I trial of the murine monoclonal anti-GD2 antibody 14G2a in metastatic melanoma, Mansoor Saleh, M B. Khazaeli, Richard Wheeler, Edward Dropcho, Tiepu Liu, Marshall Urist, Donald Miller, Sharon Lawson, Pam Dixon, and Charles Russell

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Advances in monoclonal antibody therapy of cancer, Mansoor Saleh and Albert LoBuglio

Submissions from 1991

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Evidence for the elevation of serum carcinoembryonic antigen and tumor-associated glycoprotein-72 Levels in patients administered interferons, John Greiner, Fiorella Guadagni, David Goldstein, Ernest Borden, Roy Ritts, Patricia Witt, Albert LoBuglio, Mansoor Saleh, and Jeffrey Schlom

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Intravenous immunoglobulin therapy in systemic lupus erythematosus-associated thrombocytopenia, William Maier, David Gordon, Robert Howard, Mansoor Saleh, Stephen Miller, Jefrey Lieberman, and Pamela Woodlee

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Pharmacokinetics, immune response, and biodistribution of iodine-131-labeled chimeric mouse/human IgG1, k 17-1A monoclonal antibody, Ruby Meredith, Albert LoBuglio, Walter Plott, Roger Orr, Ivan Brezovich, Charles Russell, Elizabeth Harvey, Michael Yester, and Mansoor Saleh

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Pharmacokinetics and immune response of 131I-chimeric mouse/human B72.3 (Human γ4) monoclonal antibody in humans, Mansoor Saleh, M B. Khazaeli, T P. Liu, Ruby Meredith, Richard Wheeler, Terry Baker, David King, David Secher, Laquetta Allen, and Kim Rogers

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ln-111 labeled monoclonal anti-carcinoembryonic antigen antibody (ZCE025) in the immunoscintigraphlc imaging of metastatic antigen-producing adenocarcinomas, Mansoor Saleh, Richard Wheeler, Lee Jeannette, M Khazaeli, Michael Unger, Charles Russell, and Albert LoBuglio

Submissions from 1990

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Initial evaluation of a human immunoglobulin M monoclonal antibody (HA-1A) in humans, Khazaeli M. B, Wheeler Richard, Rogers Kimberly, Teng Nelson, Ziegler Elizabeth, Haynes Amy, Mansoor Saleh, and Hardin Michael

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A phase II trial of murine monoclonal antibody 17-1A and interferon-γ: clinical and immunological data, Mansoor Saleh, Albert LoBuglio, Richard Wheeler, Kimberly Rogers, Amy Haynes, Jeannette Lee, and M B. Khazaeli

Submissions from 1989

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Effect of intravenous gammaglobulin on circulating and platelet-bound antibody in immune thrombocytopenia, G Garbano, Mansoor Saleh, P G. Mori, A F. LoBuglio, and D Shaw

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Quinidine-induced immune thrombocytopenia, Mansoor Saleh, Nadhav Dhodaphar, Karren Allen, and Albert LoBuglio

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Monocyte-platelet interaction in immune and nonimmune thrombocytopenia, Mansoor Saleh, D L. Moore, J Y. Lee, and A F. LoBuglio

Submissions from 1988

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Phase I trial of multiple large doses of murine monoclonal antibody CO17-1A. I. Clinical aspects, Albert LoBuglio, Mansoor Saleh, Jeannette Lee, M B. Khazaeli, Richard Carrano, and Howard Holden

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Phase I trial of multiple large doses of murine monoclonal antibody CO17-1A. I. Clinical aspects1, Albert LoBuglio, Mansoor Saleh, Jeannette Lee, M B. Khazaeli, Richard Carrano, and Howard Holden

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Effect of commercial immunoglobulin G preparation on human monocyte Fc-receptor dependent binding of antibody coated platelets, Mansoor Saleh, Wayne Court, William Huster, Denise Shaw, and Albert LoBuglio

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Clinical use of a standard kit-preparation of radiolabeled monoclonal antibody 96.5 in the diagnostic imaging of metastatic melanoma., Mansoor Saleh, D M. Miller, L Peterson, C D. Russell, and M W. Unger

Submissions from 1987

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Case report: immune thrombocytopenia: effects of maternal gamma globulin infusion on maternal and fetal serum, platelet, and monocyte IgG, James Burton, Mansoor Saleh, Charles Stedman, and Albert LoBuglio

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Platelet surface-bound IgG in patients with immune and nonimmune thrombocytopenia, W S. Court, Mansoor Saleh, J M. Bozeman, S J. Soong, D R. Shaw, and A F. LoBuglio

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Acute myelofibrosis and multiple chloromas of the mandible and skin, Mansoor Saleh, Brad Rodu, Josef Prchal, and Elias Romero De Leon Romero De Leon

Submissions from 1986

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Phase I clinical trial of CO17-1A monoclonal antibody., Albert LoBuglio, Mansoor Saleh, Peterson L, Wheeler R, Carrano R, and Huster W

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In vitro effects of gammaglobulin (IgG) on human monocyte Fc receptor function. I. Effect on monocyte membrane-associated IgG and Fc receptor-dependent binding of antibody-coated platelets, Mansoor Saleh, Wayne Court, and Albert Lobuglio