Acute myelofibrosis and multiple chloromas of the mandible and skin
Document Type
Article
Department
Haematology and Oncology, East Africa
Abstract
Acute myelofibrosis is a rare clinical entity characterized by severe marrow fibrosis and peripheral blood pancytopenia. It may be very closely related to and has been considered synonymous with megakaryocytic leukemia. Chloroma is also a rare entity composed of a localized collection of immature myeloid cells and is associated with a known or covert leukemia. A patient presenting with a rare combination of acute myelofibrosis, megakaryocytic leukemia and multiple chloromas of the mandible and skin, are described. Although presenting a diagnostic challenge, their combination in one patient aids in the understanding of the myeloproliferative process. To our knowledge, this is the 3rd case of chloroma involving the oral osseous structures.
Publication (Name of Journal)
International journal of oral and maxillofacial surgery
DOI
https://doi.org/10.1016/S0901-5027(87)80039-5
Recommended Citation
Saleh, M.,
Rodu, B.,
Prchal, J.,
Romero De Leon, E.
(1987). Acute myelofibrosis and multiple chloromas of the mandible and skin. International journal of oral and maxillofacial surgery, 16(1), 108-111.
Available at:
https://ecommons.aku.edu/eastafrica_fhs_mc_haematol_oncol/160
Comments
This work was published before the author joined Aga Khan University.