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Submissions from 2023

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Low-field magnetic resonance imaging in a boy with intracranial bolt after severe traumatic brain injury: Illustrative case, Awais Abbas, Kiran Hilal, Aniqa Abdul Rasool, Ume-Farwah Zahidi, Muhammad Shahzad Shamim, and Qalab Abbas

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641: Resources and inequities among pediatric critical care facilities in Pakistan, Qalab Abbas, Muhammad Zaid Hussain, Fatima Farrukh Shahbaz, Hamna Shahbaz, Mustafa Ali Khan, Naveed ur Rehman Siddiqui, Anwarul Haque, Muhammad Haroon Hamid, and Asad Latif

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Clinical and epidemiological features of pediatric population hospitalized with COVID-19: A multicenter longitudinal study (March 2020-December 2021) from Pakistan, Qalab Abbas, Farah Khalid, Fatima Farrukh Shahbaz, Javeria Khan, Shazia Mohsin, Murtaza Ali Gowa, Abdul Sattar Shaikh, Javairia Khalid, Sehrish Karim, and Fyezah Jehan

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Evaluation of the resources and inequities among pediatric critical care facilities in Pakistan, Qalab Abbas, Fatima Farrukh Shahbaz, Muhammad Zaid H. Hussain, Mustafa Ali Khan, Hamna Shahbaz, Huba Atiq, Naveed ur Rehman Siddiqu, Murtaza Ali Gowa, Hamna Shahbaz, Huba Atiq, and Naveed Ur Rehman Siddiqui

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Intestinal epithelial digestive, transport, and barrier protein expression Is increased in environmental enteric dysfunction, Shabnam Abtahi, Anne Sailer, Joseph T. Roland, Xenia Haest, Sandra D. Chanez-Paredes, Kumail Ahmed, Kamran Sadiq, Najeeha Talat Iqbal, Syed Asad Ali, and Jerrold R. Turner

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Placental inflammation and pregnancy outcomes: A prospective, observational study in South Asia: The PURPOSe study, Imran Ahmed, Najia Bano Ghanchi, Shiyam Sunder Tikmani, Kay Hwang, Afia Zafar, Sarah Saleem, Zeeshan Uddin, Sheetal Harakuni, Sheetal Harakuni, and Manjunath S. Somannavar

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Evaluation of the clinical, biochemical, and genetic presentation of neonatal and adult-onset 5,10-methylene tetrahydrofolate reductase (MTHFR) deficiency in patients from Pakistan, Sibtain Ahmed, Fizza Akbar, Ralph J. DeBerardinis, Min Ni, and Bushra Afroze

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Biorisk management, laboratory acquired infections and clinical containment, Kashif Ali, Furqan Kabir, and Esmeralda Meyer

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Can marburg virus be the next global pandemic, Raheel Allana and Asad Allana

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Bridging the equity gap through EPI immunization services in Pakistan, Raheel Allana and Rawshan Jabeen

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Differential associations between body composition indices and neurodevelopment during early life in term-born infants: Findings from the Pakistan cohort: Multi-center body composition reference study, Shabina Ariff, Almas Aamir, Aneurin Young, Laila Sikanderali, Arjumand Rizvi, Fariha Shaheen, Gul Nawaz Khan, Sajid Bashir Soofi, and Michelle Fernandes

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Has the landscape of immunotherapy for prostate cancer changed? A systematic review and post hoc analysis, Muhammad Usman Ashraf, Ume Farwa, Maryam Siddiqa, Azza Sarfraz, Nishwa Azeem, and Zouina Sarfraz

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The effectiveness of real-time computer-aided and quality control systems in colorectal adenoma and polyp detection during colonoscopies: a meta-analysis, Muhammad Fawad Aslam, Shehar Bano, Mariam Khalid, Zouina Sarfraz, Azza Sarfraz, Muzna Sarfraz, Karla Robles-Velasco, Miguel Felix, Kitson Deane, and Ivan Cherrez-Ojeda

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Asthma exacerbations and body mass index in children and adolescents: Experience from a tertiary care center, Danish Abdul Aziz, Rameen Ata Bajwa, Werdah Viquar, Fatima Siddiqui, and Aiza Abbas

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Global Initiative for Asthma (GINA) guideline: Achieving optimal asthma control in children aged 6-11 years, Danish Abdul Aziz, Muhammad Aqib Sajjad, and Ameema Asad

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Clinical outcomes of children with acute asthma managed with intravenous magnesium sulphate outside intensive care setting, Danish Abdul Aziz, Muhammad Aqib Sajjad, and Haissan Iftikhar

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Identification of potential therapeutic intervening targets by in-silico analysis of nsSNPs in preterm birth-related genes, Muhammad Bilal Azmi, Waqasuddin Khan, M Kamran Azim, Muhammad Imran Nisar, and Fyezah Jehan

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Sensitivity and specificity of wearables for atrial fibrillation in elderly populations: A systematic review, Faiza Babar, Abdul Manan Cheema, Zubair Ahmad, Azza Sarfraz, Zouina Sarfraz, Huma Ashraff, Hamnah Tayyab, Ali Mustafa Bajwa, Haider Ali, and Muzna Sarfraz

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Spatiotemporal variation in risk of Shigella infection in childhood: A global risk mapping and prediction model using individual participant data, Hamada S. Badr, Josh M. Colston, Nhat-Lan H. Nguyen, Yen Ting Chen, Eleanor Burnett, Syed Asad Ali, Ajit Rayamajhi, Syed M. Satter, Muhammad Imran Nisar, and Anita K. M. Zaidi

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Coverage survey of typhoid conjugate vaccine among children aged 6 months to 15 years in an urban slum settlement of Lyari Town Karachi, Pakistan, Rabab Batool, Sonia Qureshi, Zoya Haq, Mohammad Tahir Yousafzai, Rehana Salam, Rafey Ali, Tahira Sadaf, Miqdad Ali, and Farah Nza Qamar

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Parental acceptance of typhoid conjugate vaccine for children aged 6 months to 15 years in an outbreak setting of Lyari Town Karachi, Pakistan, Rabab Batool, Mohammad Tahir Yousafzai, Sonia Qureshi, Sajid Muhammad, Ibtisam Qazi, Tahira Sadaf, Per Ashorn, and Farah Qamar

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The global challenge of childhood obesity and its consequences: What can be done?, Zulfiqar Ahmed Bhutta, Shane A. Norris, Morven Roberts, and Atul Singhal

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The global challenge of childhood obesity and its consequences: What can be done?, Zulfiqar Ahmed Bhutta, Shane A. Norris, Morven Roberts, and Atul Singhal

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Ten years for GHSP: Where are we now? where will we go?, Zulfiqar Ahmed Bhutta, Rajani Ved, Nana Twum-Danso, Abdulmumin Saad, and Stephen Hodgins

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Mucosal transcriptomics highlight lncRNAs implicated in ulcerative colitis, crohn disease, and celiac disease, Tzipi Braun, Katya E. Sosnovski, Amnon Amir, Marina BenShoshan, Kelli L. VanDussen, Rebekah Karns, Nina Levhar, Haya Abbas-Egbariya, Rotem Hadar, and Syed Asad Ali

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Human milk micronutrients and child growth and body composition in the first 2 years: A systematic review, Meredith Merilee Brockway, Allison I. Daniel, Sarah M M. Reyes, Matthew Granger, Joann M. McDermid, Rebecca Refvik, Karanbir K. Sidhu, Suad Musse, Pooja P. Patel, and Fyezah Jehan

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Sequential viral introductions and spread of BA.1 across Pakistan provinces during the Omicron wave, Ali Raza Bukhari, Javaria Ashraf, Akber Kanji, Yusra Abdul Rehman, Maliha Yameen, Samiah Kanwar, Waqasuddin Khan, Furqan Kabir, Muhammad Imran Nisar, Rumina Hasan, and Zahra Hasan

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Global diversity and antimicrobial resistance of typhoid fever pathogens: Insights from a meta-analysis of 13,000 salmonella typhi genomes, Megan E. Carey, Zoe A. Dyson, Danielle J. Ingle, Afreenish Amir, Mabel K. Aworh, Marie Anne, Ka Lip Chew, John A. Crump, Junaid Iqbal, Rumina Hasan, Sadia Shakoor, and Farah Qamar

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Protocol for validation of the Global Scales for Early Development (GSED) for children under 3 years of age in seven countries, Vanessa Cavallera, Gillian Lancaster, Melissa Gladstone, Maureen M. Black, Gareth McCray, Ambreen Nizar, Salahuddin Ahmed, Muhammad Imran Nisar, Farzana Begum, and Fyezah Jehan

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Early infantile epileptic encephalopathy in asparagine-linked glycosylation thirteen (ALG13) gene defect and dramatic response with ketogenic diet, Prem Chand, Asna Sulaiman, Meher Angez, and Salman Kirmani

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Role of microRNA in non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH): A comprehensive review, Mah I Kan Changez, Maryam Mubeen, Monezahe Zehra, Aniqa Abdul Rasool, Anmol Mohan, Um Ul Wara, Usha Tejwaney, and Vikash Kumar

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Clinical standards for drug-susceptible TB in children and adolescents, S. S. Chiang, S. M. Graham, H. S. Schaaf, B. J. Marais, C. C. Sant’Anna, S. Sharma, J. R. Starke, R. Triasih, J. Achar, and Farhana Amanullah

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The last mile-community engagement and conditional incentives to accelerate polio eradication in Pakistan: Study protocol for a quasi-experimental trial, Jai K. Das, Amira Khan, Farhana Tabassum, Zahra Ali Padhani, Atif Habib, Mushtaq Mirani, Abdu R. Rahman, Zahid Ali Khan, Arjumand Rizvi, and Imran Ahmed

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Community mobilization and community incentivization (CoMIC) strategy for child health in a rural setting of Pakistan: Study protocol for a randomized controlled trial, Jai K. Das, Rehana A. Salam, Arjumand Rizvi, Sajid Bashir Soofi, and Zulfiqar Ahmed Bhutta

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Health behaviors and care seeking practices for childhood diarrhea and pneumonia in a rural district of Pakistan: A qualitative study, Jai Kumar Das, Faareha Siddiqui, Zahra Ali Padhani, Maryam Hameed Khan, Sultana Jabeen, Mushtaq Mirani, Shaista Mughal, Shafaq Baloch, Imtiaz Sheikh, Sana Khatoon, Khan Muhammad, Manesh Gangwani, Karim Nathani, Rehana Salam, and Zulfiqar Ahmed Bhutta

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Vulnerable newborn types: Analysis of subnational, population-based birth cohorts for 541 285 live births in 23 countries, 2000-2021, Daniel J. Erchick, E A. Hazel, J Katz, A C C. Lee, M Diaz, L S F. Wu, S Yoshida, R Bahl, Fyezah Jehan, and M Ilyas

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Multiomic signals associated with maternal epidemiological factors contributing to preterm birth in low- and middle-income countries, Camilo A. Espinosa, Waqasuddin Khan, Rasheda Khanam, Sayan Das, Javairia Khalid, Aneeta Hotwani, Ambreen Nizar, Furqan Kabir, Fyezah Jehan, and Muhammad Imran Nisar

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Comparative predictive power of serum vs plasma proteomic signatures in feto-maternal medicine, Camilo Espinosa, Said Mohammed Ali, Waqasuddin Khan, Rasheda Khanam, Jesmin Pervin, Joan T. Price, Sayedur Rahman, Tarik Hasan, Salahuddin Ahmed, and Rubhana Raqib

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Association of exercise, brain-derived neurotrophic factor, and cognition among older women: A systematic review and meta-analysis, Shahrukh Farrukh, Shagufta Habib, Amna Rafaqat, Azza Sarfraz, Zouina Sarfraz, and Hira Tariq

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Emerging therapeutic strategies for diffuse intrinsic pontine glioma: A systematic review, Shahrukh Farrukh, Shagufta Habib, Amna Rafaqat, Zouina Sarfraz, Azza Sarfraz, Muzna Sarfraz, Karla Robles-Velasco, Miguel Felix, and Ivan Cherrez-Ojeda

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Client-centered counseling and facilitation in improving modern contraceptive uptake in urban slum of Karachi Pakistan, Zoha Zahid Fazal, Noor Ul Huda Zeeshan, Ghazal Moin, Alishan Bachlany, and Yasir Shafiq

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Fresh versus frozen versus lyophilized fecal microbiota transplant for recurrent clostridium difficile infection: A systematic review and network meta-analysis, Manesh Kumar Gangwani, Muhammad Aziz, Abeer Aziz, Fnu Priyanka, Simcha Weissman, Khiem Phan, Dushyant Singh Dahiya, Zohaib Ahmed, Amir Humza Sohail, and Wade Lee-Smith

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Newborn weight nomograms in selected low and middle-income countries, Amy Sarah Ginsburg, Fyezah Jehan, Shabina Ariff, Muhammad Imran Nisar, Eric Schaefer, Valerie Flaherman, Akina Shrestha, Srijana Dongol, Victoria Laleau, and Augusto Braima de Sa

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Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders, Carolina Gracia-Diaz, Yijing Zhou, Qian Yang, Paula Espana-Bonilla, Chul-Hwan Lee, Shuo Zhang, Natàlia Padilla, Raquel Fueyo, Elisa A. Waxman, and Shahnaz H. Ibrahim

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Development of treatment-decision algorithms for children evaluated for pulmonary tuberculosis: An individual participant data meta-analysis, Kenneth S. Gunasekera, Olivier Marcy, Johanna Muñoz, Elisa Lopez-Varela, Moorine P. Sekadde, Molly F. Franke, Maryline Bonnet, Shakil Ahmed, Farhana Amanullah, and Aliya Anwar

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Does IPV boost intestinal immunity among children under five years of age? An experience from Pakistan, Atif Habib, Sajid Bashir Soofi, Imtiaz Hussain, Imran Ahmed, Zamir Hussain, Rehman Tahir, Saeed Anwar, Simon Cousens, and Zulfiqar Ahmed Bhutta

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Exploring knowledge and perceptions of polio disease and its immunization in polio high-risk areas of Pakistan, Atif Habib, Farhana Tabassum, Imtiaz Hussain, Tooba Jawed Khan, Nazia Syed, Fariha Shaheen, Sajid Bashir Soofi, and Zulfiqar Ahmed Bhutta

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High prevalence of food insecurity in peri-urban communities in Karachi, Pakistan: The flood aftermath, Kaniz Amna Haider, Zoya Surani, Ayesha Khalid, Syed Ali Jaffar Zaidi, Rumassah Chohan, and Zahra Hoodbhoy

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Experience in prenatal genetic testing and reproductive decision-making for monogenic disorders from a single tertiary care genetics clinic in a low-middle income country, Amna Hanif, Fizza Akbar, Salman Kirmani, Amyna Jaffarali, Ghulam Zainab, Ayesha Malik, Zeeshan Ansar Ahmed, and Bushra Afroze

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Implementation evaluation of a medical student-led intervention to enhance students' engagement with research: Findings and lessons learned, Mian Arsam Haroon, Ali Aahil Noorali, Abdullah Khan Khattak, Muzamil Hamid Hussain, Rohan Advani, Ashmal Sami, Asma A H. Merchant, Adnan Ali Khan, Sana Gul Baloch, Saulat Fatimi, Zainab Samad, Babar Hasan, and Muneera Rasheed

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Neurokinin 1/3 receptor antagonists for menopausal women: A current systematic review and insights into the investigational non-hormonal therapy, Fatima Hassan, Anam Saleem, Sehar Saba Samuel, Zouina Sarfraz, Azza Sarfraz, Muzna Sarfraz, and Manish Kc

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Does the CDC COVID-19 exposure assessment criteria for healthcare personnel work in a healthcare setting in Pakistan?, Imran Hassan, Unab Khan, Shehreen Ali, Asif Hakim, and Asad Ali

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Mean temperature and drought projections in Central Africa: A population-based study of food insecurity, childhood malnutrition and mortality, and infectious disease, Munum Hassan, Kinza Saif, Muhammad Saad Ijaz, Zouina Sarfraz, Azza Sarfraz, Karla Robles-Velasco, and Ivan Cherrez-Ojeda

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Body composition from birth to 2 years, Andrew P. Hills, Shane A. Norris, Nuala M. Byrne, Sisitha Jayasinghe, Alexia J. Murphy-Alford, Cornelia U. Loechl, Leila I. Cheikh Ismail, Anura V. Kurpad, Rebecca Kuriyan, and Shabina Ariff

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Routine immunization coverage and immunization card retention in Pakistan: Results from a cross-sectional national survey, Imtiaz Hussain, Ahmad Khan, Dale A. Rhoda, Imran Ahmed, Muhammad Umer, Uzair Ansari, Muhammad Akram Shah, Soofia Yunus, Sajid Bashir Soofi, and Zulfiqar Ahmed Bhutta

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Routine antibiotics for infants less than 6 months of age with growth failure/faltering: A systematic review, Aamer Imdad, Fanny F. Chen, Melissa François, Momal Sana, Emily Tanner-Smith, Abigail Smith, Olivia Tsistinas, Jai K. Das, and Zulfiqar Ahmed Bhutta

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Recent advancements in gremlin-1: Breast cancer, Nimrah Inam, Ayesha Hameed, and Lubna Vohra

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Ceftriaxone resistant Salmonella enterica serovar Paratyphi A identified in a case of enteric fever: First case report from Pakistan, Seema Irfan, Zahra Hasan, Farah Qamar, Najia Bano Ghanchi, Javaria Ashraf, Akber Kanji, Safina Abdul Razzak, David Greig, Satheesh Nair, and Rumina Hasan

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Biomarker-based risk stratification in pediatric sepsis from a low-middle income country, Sidra Ishaque, Stephen Thomas Famularo, Ali Faisal Saleem, Naveed ur Rehman Siddiqu, Zaubina Kazi, Sadia Parkar, Aneeta Hotwani, Neal J. Thomas, Jill Marie Thompson, and Patrick Lahni

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Telehealth as a public health approach to mitigate the COVID-19 pandemic in Pakistan: A narrative review, Rawshan Jabeen and Unaib Rabbani

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Referral profile of developmental disabilities at a tertiary care hospital in a resource-limited country, Sidra Kaleem Jafri, Anusha Alam, Hassan Raja, Nasreen Gulzar Ali, Fariha Shaheen, and Shahnaz Hamid Ibrahim

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Life-threatening complication: The development of necrotising fasciitis in a preterm neonate with omphalitis, Maira Jamal, Kanza Ateeque, Maida Binte Khalid Quddusi, and Farah Naz Qamar

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Remote monitoring in heart failure patients: A systemic review and meta-analysis, Syed S. Javaid, Muhammad U. Khan, Neha Saleem Paryani, Saad A. Ansari, Neha Mohiuddin, Nooraldin Merza, Naija Ehsan, Syeda T. Waheed, Muhammad S. Saleem, Haris B. Tahir, Muhammad A. Moiz, and Tariq J. Siddiqi

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Impact of enteropathogens on faltering growth in a resource-limited setting, Furqan Kabir, Junaid Iqbal, Zehra Jamil, Najeeha Talat Iqbal, Fatima Aziz, Adil Kalam, Sahrish Muneer, Aneeta Hotwani, Sheraz Ahmed, Fayyaz Umrani, Sana Syed, Kamran Sadiq, and Syed Asad Ali

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Oral and intravenous amoxicillin dosing recommendations in neonates: A pooled population pharmacokinetic study, Fleur M. Keij, Stef Schouwenburg, René F. Kornelisse, Tim Preijers, Fatima Mir, Pieter Degraeuwe, Leo M. Stolk, Arianne van Driel, Sandra Kenter, and Jacqueline van der Sluijs

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Natural coumarins from Murraya paniculata as mixed-type inhibitors of cholinesterases: In vitro and in silico investigations, Asaad Khalid, Waqasuddin Khan, Komal Zia, Aziz uddin, Waquar Ahsan, Hassan A. Alhazmi, Ashraf N. Abdalla, Asim Najmi, Andleeb Khan, and Abdelhakim Bouyahya

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Presentation of Dyke-Davidoff-Masson Syndrome in a 32-year-old female: Report of a rare case with a literature review, Muhammad Zubair Khan, Shruti Sagar Mahapatra, Tirath Patel, Waleed Razzaq, and Uzzam Ahmed Khawaja

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Building up a genomic surveillance platform for SARS-CoV-2 in the middle of a pandemic: A true North-South collaboration, Waqasuddin Khan, Furqan Kabir, Samiah Kanwar, Fatima Aziz, Sahrish Muneer, Adil Kalam, Mehdia Ali, Nadia Ansari, Fyezah Jehan, and Muhammad Imran Nisar

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Systematic review on the current state of disaster preparation simulation exercises (SimEx), Syed Sarosh Mahd, Hafsa Abrar Jafri, Raheel Allana, Gopi Battineni, Mariam Khawaja, Syeda Sakina, Daniyal Agha, Kiran Rehman, and Francesco Amenta

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Health data ecosystem in Pakistan: a multisectoral qualitative assessment of needs and opportunities, Sana Mahmood, Ali Aahil Noorali, Afshan Manji, Noreen Afzal, Saadia Abbas, Javeria Bilal Qamar, Sameen Siddiqi, Zahra Hoodbhoy, Salim S. Virani, Zulfiqar Ahmed Bhutta, and Zainab Samad

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Mental health disparities among homosexual men and minorities: A systematic review, Muhammad Hadi Malik, Shahid Iqbal, Muhammad Noman, Zouina Sarfraz, Azza Sarfraz, and Shabbir Mustafa

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Predictive biomarkers for colorectal cancer: A state-of-the-art systematic review, Moeez Maqbool, Aden Khan, Areej Shahzad, Zouina Sarfraz, Azza Sarfraz, Hinna Aftab, and Ali Jaan

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Construction and validation of ShaMaq developmental screening tool, Shazia Maqbool, Nick Brown, Aisha Farid, Anam Ali, Kamila Iftikhar, Attia Bari, Ehsan Ullah, and Shahid Hafeez

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The creation of the Global Scales for Early Development (GSED) for children aged 0-3 years: Combining subject matter expert judgements with big data, Gareth McCray, Dana McCoy, Patricia Kariger, Magdalena Janus, Maureen M. Black, Susan M. Chang, Fahmida Tofail, Iris Eekhout, Marcus Waldman, Stef van Buuren, Rasheda Khanam, Sunil Sazawal, Ambreen Nizar, and Imran Nisar

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Complementary feeding pattern and nutritional status of children, Ramlah Mehmood, Khadija Nuzhat Humayun, Ali Faisal Saleem, Asma Sherazi, and Nuzhat Asghar Ali

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Rabies in the SAARC region: An epidemiological study of disease burden and challenges, Bareea Mubashar, Sidra Iqbal, Amna Noor, Azza Sarfraz, and Zouina Sarfraz

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Body composition reference charts for infants from birth to 24 months: Multicenter infant body composition reference study, Alexia J. Murphy-Alford, William Johnson, Lukhanyo H. Nyati, Ina S. Santos, Andrew P. Hills, Shabina Ariff, V. Pujitha Wickramasinghe, Rebecca Kuriyan, M.Nishani Lucas, and Caroline S. Costa

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Feasibility of a peer-supported, WhatsApp-assisted, lifestyle modification intervention for weight reduction among adults in an urban slum of Karachi, Pakistan: A mixed-methods, single-group, pretest-post-test, quasi-experimental study, Sabahat Naz, Kaniz Amna Haider, Ali Jaffar, Umber S. Khan, Iqbal Azam Syed, Amna Siddiqui, and Romaina Iqbal

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Assessing the effectiveness of COVID-19 vaccines in Pakistan: A test-negative case-control study, Muhammad Imran Nisar, Nadia Ansari, Shahira Shahid, Kiran Ali Ramzan Ali Lalani, Maaheen Ahmed Chandna, Ayesha Mansoor Younus, Zahra Hasan, Unab Khan, Farah Khalid, Marvi Mahesar, Muhammad Farrukh Qazi, and Fyezah Jehan

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What should we be recommending for the treatment of enteric fever?, Christopher M. Parry, Farah Qamar, Samita Rijal, Naina McCann, Stephen Baker, and Buddha Basnyat

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Missense variants in RPH3A cause defects in excitatory synaptic function and are associated with a clinically variable neurodevelopmental disorder, Lisa Pavinato, Jennifer Stanic, Marta Barzasi, Antonia Gurgone, Giuseppe Chiantia, Valentina Cipriani, Ivano Eberini, Luca Palazzolo, Monica Di Luca, and Prem Chand

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Azithromycin for bacterial watery diarrhea: A reanalysis of the antiBiotics for children with severe iarrhea (ABCD) trial incorporating molecular diagnostics, Patricia B. Pavlinac, James Platts-Mills, Jie Liu, Hannah E. Atlas, Jean Gratz, Darwin Operario, Aneeta Hotwani, Furqan Kabir, Farah Qamar, and Mohammad Tahir Yousafzai

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A multicenter observational study on outcomes of moderate and severe pediatric traumatic brain injuries-time to reappraise thresholds for treatment, Syeda Kashfi Qadri, Jan Hau Lee, Yanan Zhu, Paula Caporal, Juan D. Roa G, Sebastián González Dambrauskas, Adriana Yock-Corrales, Qalab Abbas, Yasser Kazzaz, and Luming Shi

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A global systematic review and meta-analysis on the emerging evidence on risk factors, clinical characteristics, and prognosis of multisystem inflammatory syndrome in adults (MIS-A), Mohammad Aadil Qamar, Syed Shabbir Afzal, Rubaid Azhar Dhillon, Mir Ibrahim Sajid, Zouina Sarfraz, Azza Sarfraz, Mehek Narmeen, Omar Irfan, Ivan Cherrez-Ojeda, and Ali Bin Sarwar Zubairi

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Community centred co-design methodology for designing and implementing socio-behavioural interventions to counter COVID-19 related misinformation among marginalized population living in the squatter settlements of Karachi, Pakistan: A methodology paper, Rubina Qasim, Waqas Ahmed Farooqui, Atiya Rahman, Rukhsana Haroon, Madiha Saleem, Muhammad Rafique, Fiza Noor, Afifa Ghani, Muhammad Yaqoob, and Mohammad Tahir Yousafzai

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Life-threatening complication of retropharyngeal abscess in an infant: A case report, Ayaz Ur Rehman, Salman Khan, Awais Abbas, Hamdan Ahmed Pasha, Qalab Abbas, and Naveed ur Rehman Siddiqu

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Immunotherapy for prostate cancer: A current systematic review and patient centric perspectives, Laeeq Ur Rehman, Muhammad Hassan Nisar, Wajeeha Fatima, Azza Sarfraz, Nishwa Azeem, Zouina Sarfraz, and Karla Robles-Velasco

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Addressing the endometriosis knowledge gap for improved clinical care-A cross-sectional pre- and post-educational-intervention study among Pakistani women, Muhammad Saad, Aiman Rafiq, Anam Jamil, Zouina Sarfraz, Azza Sarfraz, Karla Robles-Velasco, and Ivan Cherrez-Ojeda

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Student experiences of simulation-based learning and its impact on their performance in objective structured clinical examination in pediatrics - A mixed method study, sana saeed, Azam Afzal, Farah Khalid, and Fyezah Jehan

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Process evaluation of paediatric fellowship training programs at a university hospital in Pakistan, sana saeed, Prem Chand, Asna Sulaiman, Muhammad Imran Nisar, Khadija N Humayun, Marib Ghulam Rasool Malik, and Fyezah Jehan

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Hybridizing video-based learning with simulation for flipping the clinical skills learning at a university hospital in Pakistan, sana saeed, Maryam Hameed Khan, Muhammad Muneeb Ullah Siddiqui, Anny Dhanwani, Areeba Hussain, and Muhammad Maisam Ali

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The clinical and genetic spectrum of autosomal-recessive TOR1A-related disorders, Afshin Saffari, Tracy Lau, Homa Tajsharghi, Ehsan Ghayoor Karimiani, Ariana Kariminejad, Stephanie Efthymiou, Giovanni Zifarelli, Tipu Sultan, Mehran Beiraghi Toosi, and Shahnaz Ibrahim

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Two-year duration of immunity of inactivated poliovirus vaccine: A follow-up study in Pakistan in 2020, Ali Faisal Saleem, Sadia Parkar, Syeda Mahjabeen Zehra, Zaubina Kazi, Asma Sadruddin Pethani, Yiting Zhang, Bernardo A. Mainou, Rocio Lopez Cavestany, Grace Macklin, and Visalakshi Jeyaseelan

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Infant body composition at 6 and 24 months: What are the driving factors?, Ina S. Santos, Caroline S. Costa, Andrew P. Hills, Shabina Ariff, V Pujitha Wickramasinghe, Shane Norris, Alexia J. Murphy-Alford, Christine Slater, Nishani Lucas, and Lukhanyo H. Nyati

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Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural community of Pakistan, Azza Sarfraz, Sheraz Ahmed, Sajid Muhammad, Najeeb Rehman, Sanam Iram Soomro, Abdul Khaliq Qureshi, Sadaf Jakhro, Fayyaz Umrani, Sana Syed, and Syed Asad Ali

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Impact of diarrhoea and acute respiratory infection on environmental enteric dysfunction and growth of malnourished children in Pakistan: A longitudinal cohort study, Azza Sarfraz, Zehra Jamil, Sheraz Ahmed, Fayyaz Umrani, Abdul Khaliq Qureshi, Sadaf Jakhro, Muhammad Sajid, Najeeb Rehman, Arjumand Rizvi, Najeeha Talat Iqbal, Sana Syed, Junaid Iqbal, Kamran Sadiq, and Syed Asad Ali

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Differential coverage for vaccines in the expanded program on immunization (EPI) among children in rural Pakistan, Shahira Shahid, Sheraz Ahmed, Muhammad Farrukh Qazi, Rafey Ali, Syed Asad Ali, Anita K. M. Zaidi, Najeeha Talat Iqbal, Fyezah Jehan, and Muhammad Imran Nisar

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Knowledge, attitudes, and practices towards seasonal influenza vaccination among pregnant women and healthcare workers: A cross-sectional survey in Afghanistan, Shahira Shahid, Shafi Kalhoro, Hajra Khwaja, Mohammad Asif Hussainyar, Junaid Mehmood, Muhammad Farrukh Qazi, Abdinasir Abubakar, Shaza Mohamed, Fyezah Jehan, and Muhammad Imran Nisar

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Inappropriate supplementation of Vitamin D can result in toxicity: A crosssectional study of paediatrics population, Nazia Shamim, Hafsa Majid, Suneeta Khemani, Maliha Salim, Siraj Muneer, and Aysha Habib

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Pulse oximetry: Why oxygen saturation is still not a part of standard pediatric guidelines in low-and-middle-income countries (LMICs), Maheen Sheikh, Huzaifa Ahmad, Romesa Ibrahim, Muhammad Imran Nisar, and Fyezah Jehan