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Submissions from 2000

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Synergistic interaction of adrenaline and histamine in human platelet aggregation is mediated through activation of phospholipase, map kinase and cyclo-oxygenase pathways, B H. Shah, I Lashari, S Rana, O Saeed, H Rasheed, and S Arshad Saeed

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Low serum alpha 1 antitrypsin in duodenal ulcer--a family study, Anjum Shahid; Sarwar J; Zuberi Mohammad A; Waqar,Huma Qureshi Waqar,Huma Qureshi Waqar,Huma Qureshi; Anwar Ali Siddiqui; and Taranum Sultana

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Phenotypes of Alpha 1 Antitrypsin in Karachi, Pakistan, Anjum Shahid, Anwar Ali Siddiqui, Sarwar i J. Zuberi, and Mohammad Waqar

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Serotonin inhibits luteinizing hormone release via 5-HT1A receptors in the zona incerta of ovariectomised, anaesthetised rats primed with steroids, A Siddiqui, K Kotecha, A M. Salicioni, V Kalia, J F. Murray, and C A. Wilson

Submissions from 1999

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Atherosclerosis and plaque rupture: An update, M N. Afzal, S A. Saeed, and B H. Shah

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Possible mechanism of selective inotropic activity of the n-butanolic fraction from Berberis aristata fruit, A H. Gilani, K H. Janbaz, N Aziz, M J. Herzig, M M. Kazmi, M I. Choudhary, and J W. Herzig

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Studies on antihypertensive and antispasmodic activities of methanol extract of Acacia nilotica pods, A H. Gilani, F Shaheen, M Zaman, K H. Janbaz, B H. Shah, and M S. Akhtar

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Additive effect of indomethacin and methotrexate on suppression of growth in rats, M P. Iqbal, S A. Saeed, S Pertani, and N Mehboobali

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Detection of lactate dehydrogenase isoenzyme-M in body fluids containing albumin, M H. Javed, A H. Jafri, and F A. Yousuf

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Effect of amino acids on inhibition of lactate dehydrogenase-X by gossypol, M H. Javed and M A. Khan

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GroEL protects the sarcoplasmic reticulum Ca(++)-dependent ATPase from inactivation in vitro, M U. Javed, F Michelangeli, and P A. Lund

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Ca2+ sensitization of myocardial force and actomyosin ATPase by (D-Ala2, Met5) enkephalinamide, H Loewe, I Baeger, A Knoll, and J W. Herzig

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Cholera toxin mediated regulation of the expression of Gq alpha and G11 alpha GTP binding proteins, B H. Shah

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Inhibitory effect of curcumin, a food spice from turmeric, on platelet-activating factor- and arachidonic acid-mediated platelet aggregation through inhibition of thromboxane formation and Ca2+ signaling, B H. Shah, Z Nawaz, S A. Pertani, A Roomi, H Mahmood, S A. Saeed, and A H. Gilani

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Co-activation of Gi and Gq proteins exerts synergistic effect on human platelet aggregation through activation of phospholipase C and Ca2+ signalling pathways, B H. Shah, A Siddiqui, K A. Qureshi, M Khan, S Rafi, V A. Ujan, M Y. Yakoob, Y Yaqub, H Rasheed, and S A. Saeed

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Physiology teaching in the developing world: models for quality learning, A Siddiqui

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Risk of transmission and features of hepatitis C after needlestick injuries., Hamid SS, Farooqui B, Rizvi Q, Sultana T, and Anwar Ali Ali Siddiqui

Submissions from 1998

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Esculetin prevents liver damage induced by paracetamol and CCL4, A H. Gilani, K H. Janbaz, and B H. Shah

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Accumulation of methotrexate in human tissues following high-dose methotrexate therapy, M P. Iqbal

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Urinary N-acetyl-beta-D-glucosaminidase in rheumatoid arthritis, M P. Iqbal, A A. Ali, M A. Waqar, and N Mehboobali

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The effects of non-steroidal anti-inflammatory drugs on the disposition of methotrexate in patients with rheumatoid arthritis, M P. Iqbal, J A. Baig, A A. Ali, S K. Niazi, N Mehboobali, and M A. Hussain

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A simple method for the detection of lactate dehydrogenase isoenzymes M:H ratio by gel filtration, M H. Javed and T Y. Naru

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Dual effects of nimesulide, a COX-2 inhibitor, in human platelets, S A. Saeed, M N. Afzal, and B H. Shah

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Myocardial ischaemia and infarction in isoprenaline-treated rabbits: role of cyclooxygenases, S A. Saeed, A H. Gilani, B H. Sultan, R M. Karim, and B H. Shah

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The inhibitory effect of cinchonine on human platelet aggregation due to blockade of calcium influx, Bukhtiar H. Shah, Zafar Nawaz, Salim S. Virani, Imran Q. Ali, S A. Saeed, and Anwar H. Gilani

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Cerebrospinal fluid proteins in meningitis, Anwar Ali Siddiqui, TAJBIBI Z. Ali, NASEEMA M. Ali, M KHURSHIDt, and MOHAMMAD A. WAQAR

Submissions from 1997

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Quercetin exhibits hepatoprotective activity in rats, A H. Gilani, K H. Janbaz, and B H. Shah

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Interaction of ebeinone, an alkaloid from Fritillaria imperialis, at two muscarinic acetylcholine receptor subtypes, A H. Gilani, F Shaheen, A Christopoulos, and F Mitchelson

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Low serum HDL-cholesterol is associated with raised tumor necrosis factor-alpha during ENL reactions, R A. Memon, A Kifayet, F Shahid, A Lateef, J Chiang, and R Hussain

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Anti-thrombotic and anti-inflammatory activities of protopine, S A. Saeed, A H. Gilani, R U. Majoo, and B H. Shah

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The inhibition of prostaglandin biosynthesis by human haptoglobin and its relationship with haemoglobin binding, S A. Saeed, F Mahmood, B H. Shah, and A H. Gilani

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Effects of lipoproteins on cyclo-oxygenase and lipoxygenase pathways in human platelets, S A. Saeed, R A. Memon, A H. Gilani, and B H. Shah

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Diversity of agonist-mediated signal transduction pathways in human platelets, S A. Saeed and B H. Shah

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Enhanced degradation of stimulatory G-protein (Gs alpha) by cholera toxin is mediated by ADP-ribosylation of Gs alpha protein but not by increased cyclic AMP levels, B H. Shah

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Dopamine potentiation of calcium ionophore, A-23187-induced platelet aggregation, B H. Shah, S A. Saeed, F Rashid, and A H. Gilani

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Role of phosphatidylinositol 3-kinase in human platelet aggregation, B H. Shah, S A. Saeed, G Shamim, Z Nawaz, and A H. Gilani

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The antiplatelet aggregatory activity of Acacia nilotica is due to blockade of calcium influx through membrane calcium channels, Bukhtiar H. Shah, Basmah Safdar, Salim S. Virani, Z Nawaz, S A. Saeed, and A H. Gilani

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Genetic Markers and Duodenal Ulcer, Anjum Shahid, Sarwar J. Zuberi, Anwar Ali Siddiqui, and Muhamined A. Waqar Muhamined A. Waqar Muhamined A. Waqar

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Perinatal exposure to morphine disrupts brain norepinephrine, ovarian cyclicity, and sexual receptivity in rats, A Siddiqui, S Haq, and B H. Shah

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Neonatal androgen manipulation differentially affects the development of monoamine systems in rat cerebral cortex, amygdala and hypothalamus, A Siddiqui and B H. Shah

Submissions from 1996

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Dynamic and steady state response of heart rate to orthostatic stress in normotensive and hypertensive pregnant women, H R. Ahmad, S Akhtar, M A. Khan, K S. Khan, A A. Qureshi, H Romana, and P F. Hughes

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Bronchodilator response in pulmonary disease at two different states of respiratory mechanics, H R. Ahmad, H H. Rayani, C W. Vellani, M A. Khan, and S R. Zaidi

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Selective protective effect of an extract from Fumaria parviflora on paracetamol-induced hepatotoxicity, A H. Gilani, K H. Janbaz, and M S. Akhtar

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Inhibition studies on LDH isoenzyme purified from Uromastix testes, M U. Javed and M A. Waqar

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Alterations in serum lipids in lepromatous leprosy patients with and without ENL reactions and their relationship to acute phase proteins, R A. Memon, R Hussain, J G. Raynes, A Lateff, and T J. Chiang

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Protein kinase C inhibitor, chelerythrine, potentiates the adrenaline-mediated aggregation of human platelets through calcium influx, B H. Shah, G Shamim, S Khan, and S A. Saeed

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Serum Alpha 1 Antitrypsin and Pulmonary Emphysema, Anjum Shahid, Salimuddin Aziz, Sarwar J. Zuben, Anwar Ali Siddiqui, Musawir Ansari, and Mohammed Anwar Waqar

Submissions from 1995

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Volume history response of airway resistance, H R. Ahmad, M A. Khan, M Memon, and M N. Khan

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Preventive and curative effects of Artemisia absinthium on acetaminophen and CCl4-induced hepatotoxicity, A H. Gilani and K H. Janbaz

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Studies on protective effect of Cyperus scariosus extract on acetaminophen and CCl4-induced hepatotoxicity, A U. Gilani and K H. Janbaz

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Basic medical research as a means of solving national health problems, M. Perwaiz Iqbal and M Anwar Waqar

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Pharmacokinetics of aditoprim in normal and febrile sheep, M P. Iqbal, S K. Niazi, M K. Ashfaq, and N Mahboobali

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Disposition kinetics of aditoprim in two monkeys in comparison to other mammalian species, M P. Iqbal, S K. Niazi, N Mehboobali, and A A. Zaidi

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Protective effect of histidine by inhibition of gossypol on rat's liver LDH-5, M H. Javed and M A. Waqar

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Purification and properties of lactate dehydrogenase from liver of Uromastix hardwickii, M U. Javed, F A. Yousuf, A N. Hussain, M Ishaq, and M A. Waqar

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Impaired mitochondrial metabolism and reduced amphibolic Krebs cycle activity in diabetic rat hepatocytes, R A. Memon, S P. Bessman, and C Mohan

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An update on hyperlipidemia and its management, R A. Memon and A H. Gilani

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Impaired mitochondrial protein synthesis in streptozotocin diabetic rat hepatocytes, R A. Memon, C Mohan, and S P. Bessman

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Altered platelet activating factor metabolism in insulin dependent diabetes mellitus, R A. Memon, S A. Saeed, A Jabbar, A Jafri, A H. Gilani, S Saleem, and H Akbani

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Eugenol: a dual inhibitor of platelet-activating factor and arachidonic acid metabolism, S A. Saeed, R U. Simjee, G Shamim, and A H. Gilani

Phosphatidylinositol 3-kinase inhibitor, wortmannin, inhibits 5-hydroxytryptamine-mediated potentiation of platelet aggregation induced by epinephrine, B H. Shah and S A. Saeed

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Genetic Variants of Serum Alpha 1 Antitrypsin, Anjum Shahid, Anwar Ali Siddiqui, Mohammed Anwar Waqar, and Sarwar J. Zuberi

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Morphine induces reproductive changes in female rats and their male offspring, A Siddiqui, S Haq, S Shaharyar, and S G. Haider

Submissions from 1994

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Evaluation of the liver protective potential of Cichorium intybus seed extract on Acetaminophen and CCl(4)-induced damage, A H. Gilani and K H. Janbaz

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Hepatoprotective effects of artemisia scoparia against carbon tetrachloride: An environmental contaminant, A H. Gilani and K H. Janbaz

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Possible presence of calcium channel blocker(s) in Rubia cordifolia: An indigenous medicinal plant, A H. Gilani, K H. Janbaz, M Zaman, A Lateef, A Suria, and H R. Ahmed

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Pharmacokinetics of aditoprim and trimethoprim in buffalo calves, M P. Iqbal, M K. Ashfaq, S K. Niazi, M Mahboobali, and K N. Khawaja

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The isoenzyme forms of lactate dehydrogenase from the testes of Uromastix hardwickii, M H. Javed, M A. Qureshi, and M A. Waqar

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Differential effects of anti-asthmatic drugs on arachidonic acid and platelet-activating factor, S A. Saeed, N Ali, and S Saleem

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Antithrombotic activity of clove oil, Shaikh A. Saeed and A H. Gilani

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Serum Alpha 1 Antitrypsin in Liver Diseases, Anjum Shahid, Anwar Ali Siddiqui, Sarwar J. Zuberi, and M A. Waqar

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Evidence for involvement of amino acid neurotransmitters in anesthesia and naloxone induced reversal of respiratory paralysis, A Suria and F Rasheed

Submissions from 1993

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Protective effect of Artemisia scoparia extract against acetaminophen-induced hepatotoxicity, A H. Gilani and K H. Janbaz

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Severe bone marrow suppression in a patient with rheumatoid arthritis on methotrexate, M P. Iqbal, A A. Ali, and A A. Alvi

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Effect of folates and folate antagonists on lipid peroxidation, M P. Iqbal, N Mehboobali, and M A. Waqar

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Thymidylate synthase in normal and cancer tissues, M P. Iqbal, H Zuberi, M A. Waqar, and M Ahmed

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Triterpenes and B-sitosterol from piper betle: isolation, antiplatelet and anti-inflammatory effects, S A. Saeed, S Farnaz, R U. Simjee, and A Malik

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Modulation of cyclic AMP-dependent protein kinase activity by drugs affecting human platelet aggregation, S A. Saeed, M H. Javed, and G Ashraf

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Inhibition of platelet aggregation and arachidonic acid metabolism by B-carboline alkaloids, S A. Saeed, R U. Simjee, S Farnaz, A H. Gilani, S Siddiqui, B S. Siddiqui, S Begum, S Faizi, and A Zia

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Dual inhibition of platelet-activating factor and arachidonic acid metabolism by ajmaline and effect on carrageenan-induced rat paw oedema, S A. Saeed, R U. Simjee, F Mahmood, and N N. Rahman

Submissions from 1992

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Effect of dehydration on the disposition kinetics of erythromycin in rabbits, M Ahmad, S K. Niazi, T Ahmad, N A. Muzaffar, and M Nawaz

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Effect of harmalol on blood pressure in anaesthetized rats, A H. Gilani, K Aftab, S A. Saeed, and A Suria

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Prevention of acetaminophen-induced liver damage by Berberis aristata leaves, A H. Gilani and K H. Janbaz

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Presence of arachidonic acid-like substance(s) in Thevitia neriifolia, A H. Gilani, F Shaheen, Q Adil, S Begum, B S. Siddiqui, and S Siddiqui

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Methotrexate as an alternative to surgery in ectopic pregnancy: A new role for an old drug, M P. Iqbal

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Appearance of a methotrexate binding plasma protein during high dose methotrexate therapy, M P. Iqbal, I Malik, and N Mehboobali

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Estimation and separation of N-acetyl-beta-D-glucosaminidase isoenzymes in urine, M H. Javed, A N. Hussain, and M A. Waqar

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Heat-stabilizing factor of lactate dehydrogenase in the skeletal muscle of Uromastix, M H. Javed, A N. Hussain, and M A. Waqar

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8-Hydroxyquinoline and its derivatives: potential inhibitors of platelet aggregation, S A. Saeed, R U. Simjee, A H. Gilani, S Siddiqui, R Saleem, S Faizi, B Siddiqui, and S Farnaz

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Isolation and Partial Characterisation of Renal Stone Proteins, Anwar Ali Ali Siddiqui and M A. Waqar

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Effect of dexamethasone on collagen synthesis in fibroblasts cultured in collagen lattice., Anwar Ali Siddiqui, T Jaffar, N Khan, R Azami, and M A. Waqar

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LOW MOLECULAR WEIGHT PROTEOGLYCANS FROM RENAL STONES, Anwar Ali Siddiqui, N Nmn, M A. Waqar, and J Talati

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Socially available heroin powders--their chemical compositions and reproductive and behavioural effects on female rats, A Siddiqui, A A. Zaidi, S Khatoon, C Sultana, V Sultana, and Z H. Zaidi

Submissions from 1991

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A sensitive enzyme-linked immunosorbent assay for dihydrofolate reductase, M P. Iqbal and R Hussain

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Yeast cells with a low-affinity binder of methotrexate, M P. Iqbal, N Mehboobali, and M A. Waqar

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Heterogeneity of methotrexate binding in human colon tumor cells, M P. Iqbal, N Mehboobali, M A. Waqar, and M Ahmed

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Dihydrofolate reductase from a reptile, uromastix, M P. Iqbal, N Mehboobali, M A. Waqar, and H S. Zuberi

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Evidence for kinetic and immunologic heterogeneity of dihydrofolate reductase in L1210 leukemia cells, M P. Iqbal, S P. Rothenberg, and Costa M. da

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c-AMP-dependent protein kinases in human tissues, M H. Javed, G Ashraf, and M A. Waqar

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Protein kinase-C in rat brain and human tissues, M H. Javed, G Ashraf, and M A. Waqar