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Submissions from 2006

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Brain tumor stem cells: role in neurooncogenesis and therapeutic implications, Muhammad Zeeshan Ozair, Adil Hameed Khan, and S. Ather Enam

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Role of the Sulfolobus shibatae viral T6 initiator in conferring promoter strength and in influencing transcription start site selection, Sohail A. Qureshi

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Critical evaluation of the claims made by pharmaceutical companies in drug promotional material in Pakistan, Dileep Kumar Rohra, Anwarul Hassan Gilani, Ismail Kamal Memon, Ghazala Perven, Muhammad Talha Khan, Hina Zafar, and Rakesh Kumar

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3120+1 G-->A: A rare variant in Emirati CF patients, Danish Saleheen and Philippe M. Frossard

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[3120+1kbdel86kb]+[pN1303K] genotype in an Emirati cystic fibrosis patient: indication of a founder mutation in Palestinian Arabs, Danish Saleheen, Philippe M. Frossard, and Emmanuelle Girodon

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The changing shape of teaching physiology in South Asia: problems and prospects, Arif Siddiqui

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Enhanced detection rate of typhoid fever in children in a periurban slum in Karachi, Pakistan using polymerase chain reaction technology., Nizami SQ, Bhutta ZA, Anwar Ali Siddiqui, and Lubbad L

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Correlation between translation efficiency and outcome of combination therapy in chronic hepatitis C genotype 3, A Yasmeen, S Hamid, Granath FN, Lindström H, Anwar Ali Siddiqui, and Persson MA

Submissions from 2005

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Strong association of a renin intronic dimorphism with essential hypertension, Usman Ahmad, Danish Saleheen, Awais Bokhari, and Philippe M. Frossard

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Gastrointestinal stimulatory and uterotonic activities of dietary radish leaves extract are mediated through multiple pathways, Muhammad Nabeel Ghayur and Anwarul Hassan Gilani

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Ginger lowers blood pressure through blockade of voltage-dependent calcium channels, Muhammad Nabeel Ghayur and Anwarul Hassan Gilani

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Pharmacological basis for the medicinal use of ginger in gastrointestinal disorders, Muhammad Nabeel Ghayur and Anwarul Hassan Gilani

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Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways, Muhammad Nabeel Ghayur, Anwarul Hassan Gilani, Maria B. Afridi, and Peter J. Houghton

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Species differences in the gut stimulatory effects of radish seeds, Muhammad Nabeel Ghayur, Anwarul Hassan Gilani, and Peter J. Houghton

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Studies on the antihypertensive, antispasmodic, bronchodilator and hepatoprotective activities of the Carum copticum seed extract, A H. Gilani, Q Jabeen, M N. Ghayur, K H. Janbaz, and M S. Akhtar

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Pharmacological basis for the use of Fumaria indica in constipation and diarrhea, Anwar H. Gilani, Samra Bashir, Khalid H. Janbaz, and Arifullah Khan

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Presence of cholinergic and calcium channel blocking activities explains the traditional use of Hibiscus rosasinensis in constipation and diarrhoea, Anwar H. Gilani, Samra Bashir, Khalid H. Janbaz, and Abdul Jabbar Shah

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Cholinomimetic and calcium channel blocking activities of Carthamus oxycantha, Anwar H. Gilani, Ishfaq A. Bukhari, Rafeeq A. Khan, Arif-ullah Khan, Farman Ullah, and Viqar U. Ahmad

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Antispasmodic and blood pressure lowering effects of Valeriana wallichii are mediated through K+ channel activation, Anwar H. Gilani, Arif-ullah Khan, Qaiser Jabeen, Fazal Subhan, and Rukhsana Ghafar

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Blood pressure lowering effect of olive is mediated through calcium channel blockade, Anwarul Hassan Gilani, Arif-Ullah Khan, Abdul Jabbar Shah, John Connor, and Qaiser Jabeen

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Antispasmodic and bronchodilator activities of St John's wort are putatively mediated through dual inhibition of calcium influx and phosphodiesterase, Anwarul Hassan Gilani, Arif-ullah Khan, Fazal Subhan, and Munasib Khan

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Trends in ethnopharmocology, Anwarul Hassan Gilani and Attar-ur Rahman

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Pharmacological basis for the use of turmeric in gastrointestinal and respiratory disorders, Anwarul Hassan Gilani, Abdul Jabbar Shah, Muhammad Nabeel Ghayur, and Kashif Majeed

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Hepatoprotective activity of aqueous-methanol extract of Artemisia vulgaris, Anwarul Hassan Gilani, Sheikh Yaeesh, Qamar Jamal, and M Nabeel Ghayur

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Presence of antispasmodic, antidiarrheal, antisecretory, calcium antagonist and acetylcholinesterase inhibitory steroidal alkaloids in Sarcococca saligna, Anwar-ul Hassan Giliani, Mohammad Nabeel Ghayur, Asaad Khalid, Zaheer-ul-Haq, Muhammad Iqbal Choudhary, and Atta-ur-Rahman

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Lack of association of methylenetetrahydrofolate reductase 677C>T mutation with coronary artery disease in a Pakistani population, M Perwaiz Iqbal, Tasneem Fatima, Siddiqa Parveen, Farzana A. Yousuf, Majid Shafiq, Naseema Mehboobali, Abrar H. Khan, Iqbal Azam, and Philippe M. Frossard

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N-acetyl-beta-D-glucosaminidase--a marker of reperfusion and a prognostic indicator in patients with acute myocardial infarction, M Perwaiz Iqbal, Khawar Kazmi, and Naseema Mehboobali

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Variability in lipid profile before and after coronary artery bypass grafting (CABG), M Perwaiz Iqbal, Hasanat Mohammad Sharif, and Naseema Mehboobali

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Role of vitamins B6, B12 and folic acid on hyperhomocysteinemia in a Pakistani population of patients with acute myocardial infarction, M P. Iqbal, M Ishaq, K A. Kazmi, F A. Yousuf, N Mehboobali, S A. Ali, A H. Khan, and M A. Waqar

G-protein beta-3 subunit gene 825C>T dimorphism is associated with left ventricular hypertrophy but not essential hypertension, M Saeed Mahmood, Zainul Sajadeen Urfy Mian, Atif Afzal, and Philippe M. Frossard

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Reliability of rodent animal models in biomedical research, Dileep Kumar Rohra, Ali Jawaid, Tauseef-ur-Rehman, and Ali Hyder Zaidi

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Biochemical screening for the prediction of preeclampsia, Dileep Kumar Rohra and Nazia Qidwai

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Acidosis-induced relaxation of human internal mammary artery is due to activation of ATP-sensitive potassium channels, Dileep Kumar Rohra, Hasanat Mohammad Sharif, Hina Saeed Zubairi, Kiran Sarfraz, Muhammad Nabeel Ghayur, and Anwarul Hassan Gilani

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Association of angiotensin converting enzyme gene polymorphisms with left ventricular hypertrophy, Mohammad Saeed, Danish Saleheen, Sammer Siddiqui, Aisha Khan, Zahid A. Butt, and Philippe M. Frossard

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Association of ACE polymorphisms with left ventricular hypertrophy, Mohammad Saeed, Sammer Siddiqui, Aisha Khan, Zahid A. Butt, S Hasan Parvez, and Philippe M. Frossard

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Fractals analysis of cardiac arrhythmias, Mohammed Saeed

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ABCA1, ApoA-I and type II DM, Danish Saleheen

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The "eye of the tiger" sign, Danish Saleheen, Philippe Frossard, Mahammed Zeeshan Ozair, Mohammad Ali Kazmi, Hamza Khalid, and Bhojo Khealani

Submissions from 2004

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Presence of cholinomimetic and acetylcholinesterase inhibitory constituents in betel nut, Anwar H. Gilani, M Nabeel Ghayur, Zafar S. Saify, Shahida P. Ahmed, M Iqbal Choudhary, and Asaad Khalid

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Pharmacological basis for the gut stimulatory activity of Raphanus sativus leaves, Anwarul Hassan Gilani and M Nabeel Ghayur

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Core concepts in biochemistry and molecular biology in an integrated MBBS curriculum, M P. Iqbal

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Myoglobin--a marker of reperfusion and a prognostic indicator in patients with acute myocardial infarction, M Perwaiz Iqbal, Khawar A. Kazmi, Naseema Mehboobali, and Abdul Rahbar

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Association study of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with myocardial infarction, M Perwaiz Iqbal, Saeed Mahmood, Naseema Mehboobali, Mohammad Ishaq, Tasnim Fatima, Saddiqa Parveen, and Philippe Frossard

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Increased levels of erythrocyte glutathione in acute myocardial infarction: An antioxidant defence, M P. Iqbal, M Ishaq, and N Mehboobali

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Variability in lipid profile in patients with acute myocardial infarction from two tertiary care hospitals in Pakistan, M P. Iqbal, M Shafiq, N Mehboobali, S P. Iqbal, and K Abbasi

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Head and neck cancer susceptibility: a genetic marker in the methylenetetrahydrofolate reductase gene, Nelofar Kureshi, Shehzad Ghaffar, Sammer Siddiqui, Iftikhar Salahuddin, and Philippe M. Frossard

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Gene markers and complex disorders: A review, M S. Mahmood, N Kureshi, and P M. Frossard

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Invasive aspergillosis with polyarthritis, S F. Mekan, O Saeed, and J A. Khan

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Involvement of thromboxane A2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation, Huma Rasheed and Sheikh Arshad Saeed

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Immunity in medicine, M Saeed

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A closer look at food allergy and intolerance, Sheikh Arshad Saeed, Rahmat Ali, Saad Shahid Ali, Nabeel Ahmad, Abdul Basit, and Mian Zainul Urfy

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Signaling mechanisms mediated by G-protein coupled receptors in human platelets, Sheikh Arshad Saeed, Huma Rasheed, Faisal A Wahed Fecto, Mohammad Ilyas Achakzai, Rahmat Ali, John Dennis Connor, and Anwar-ul-Hassan Gilani

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CAD risk factors and acute myocardial infarction in Pakistan, Danish Saleheen and Philippe Frossard

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5-HT7 receptor subtype as a mediator of the serotonergic regulation of luteinizing hormone release in the zona incerta, Arif Siddiqui, Mahmoud Abu-Amara, Cyrielle Aldairy, James J. Hagan, and Catherine Wilson

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Molecular identity, expression and functional analysis of interleukin-1alpha and its isoforms in rat testis, T Sultana, K V. Svechnikov, K Gustafsson, A Wahlgren, E Tham, G Weber, and O Soder

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Cystic breast lymphangioma, S N. Waqar, H Khan, S F. Mekan, N Kayani, and A J. Raja

Submissions from 2003

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Renal cortical necrosis: A case series of nine patients & review of literature, Syed Sohail Ali, Syed Zulfiqar Rizvi, Suhail Muzaffar, Aasim Ahmad, Akhtar Ali, and Sheema H. Hassan

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Cardiac acceleration as a marker of vagal withdrawal in heart rate control during exercise in humans, S S I Bokhari, H R. Ahmad, M M F Subhan, S A. Ali, and M N. Khan

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N-acetyl-beta-D-glucosaminidase in acute myocardial infarction, M Perwaiz Iqbal, Khawar A. Kazmi, Hasan R. Jafri, and Naseema Mehboobali

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Methylene tetrahydrofolate reductase gene and coronary artery disease, M P. Iqbal and P M. Frossard

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Effect of methotrexate and folinic acid on accumulation of iron in mice, M P. Iqbal, N Mehboobali, F Sultana, F B. Khan, I A. Burney, and G N. Kakepoto

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Enzymatic method for assaying calcium in serum with Ca++ -ATPase, Masood-ul-Hassan Javed and Francesco Michelangeli

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Expression of G protein alpha subunits in the lateral wall of the rat cochlea, Khalid M. Khan, Noorjehan Sarfaraz, Sammer Siddiqui, Zainab A. Malik, and Zeenat Salim

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The in vivo antifungal activity of the aqueous extract from Nigella sativa seeds, M A U Khan, M K. Ashfaq, H S. Zuberi, M S. Mahmood, and A H. Gilani

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The in vitro effect of aqueous extract of Nigella sativa seeds on nitric oxide production, M Saeed Mahmood, A H. Gilani, Afsheen Khwaja, Ayesha Rashid, and M K. Ashfaq

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Blood lead levels during pregnancy and pregnancy outcome in Karachi women, A Rahman and A Hakeem

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Effects of changes in pH on the contractility of vascular smooth muscle, Dileep Kumar Rohra

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Association of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with essential hypertension, M Saeed Mahmood, K Saboohi, Ali S. Osman, A M. Bokhari, and P M. Frossard

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Calcium-dependent synergistic interaction of platelet activating factor and epinephrine in human platelet aggregation, Sheikh Arshad Saeed and Huma Rasheed

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Synergism interaction between arachidonic acid by 5-hydroxytryptamine in human platelet aggregation is mediated through multiple signalling pathways, Sheikh Arshad Saeed, Huma Rasheed, and Anwar-ul-Hassan Gilani

Submissions from 2002

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Kushta(s): unique herbo-mineral preparations used in South Asian traditional medicine, N Aziz, A H. Gilani, and M A. Rindh

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A study of five human cytokine genes in human essential hypertension, Philippe M. Frossard, Abha Gupta, Vera Pravica, Chris Perrey, Ian V. Hutchinson, and Miodrag L. Lukic

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Lead-associated deficits in stature, mental ability and behaviour in children in Karachi, Abdur Rahman, Erum Maqbool, and Hina S. Zuberi

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Lead levels in primary teeth of children in Karachi, Abdur Rahman and Farzana Abubakar Yousuf

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Establishing clinical pharmacy services in a Pakistani intensive care unit, Zaidi Syed Tabish Razi, Sheikh Abdul Latif, and Raza Syed Shamim

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Plasma from rheumatoid patients taking low dose methotrexate enhances platelet aggregation, S A. Saeed, A H. Gilani, H Rasheed, F N. Bhatti, M Atiq, A Qureshi, R Jafary, and J D. Connor

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Latent activity of curcumin against leishmaniasis in vitro, Danish Saleheen, Syed Atif Ali, Khalid Ashfaq, Anwar Ali Siddiqui, Ajmal Agha, and Muhammad Masoom Yasinzai

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Determination of Alpha-i Antitrypsin Genetic Deficiency in Duodenal Ulcer by Polymerase Chain Reaction, A Shahid, H Qureshi, S J. Zuberi, Anwar Ali Siddiqui, T Sultana, and M A. Waqar

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Hepatitis E virus superinfection in patients with chronic liver disease, Hamid SS; Atiq M; Shehzad F; Yasmeen A,; Nissa T; Salam A; Anwar Ali Siddiqui; and Jafri W

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Unilateral gynaecomastia--an unusual presentation of thyrotoxicosis, S Tauheed and M N. Haque

Submissions from 2001

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Intercept shift in the breathlessness/ventilation relationship in response to progressive increase in workload: change in exercise breathlessness response, H R. Ahmad, M M. Subhan, S Bokhari, A Ali, and M N. Khan

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Second messengers in platelet aggregation evoked by serotonin and A23187, a calcium ionophore, J D. Connor, H Rasheed, A H. Gilani, M Cheema, Z Rizvi, and S A. Saeed

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Bronchodilator, spasmolytic and calcium antagonist activities of Nigella sativa seeds (Kalonji): a traditional herbal product with multiple medicinal uses, A H. Gilani, N Aziz, I M. Khurram, K S. Chaudhary, and A Iqbal

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Induction of white cell proliferation due to haematopoietic growth factors is associated with an increase in multiple forms of dihydrofolate reductase in non-neutropenic cancer patients, M P. Iqbal, I A. Burney, F Sultana, and N Mehboobali

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Folinic acid protects against suppression of growth by Methotrexate in mice, M. Perwaiz Iqbal, Fakhara Sultana, Naseema Mehboobali, and Shahid Pervez

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An enzymatic method for the detection of human serum albumin, M U. Javed and S N. Waqar

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Problem-based learning variant: Transition phase for a large institution, I Khan and A Fareed

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Nitric oxide mediated effect of cyclo-oxygenase inhibitors, M Mahmood, H S. Zuberi, and M K. Ashfaq

Wortmannin inhibits platelet aggregation produced by interaction of gamma-aminobutyric acid and the calcium tonophore, A23187, S A. Saeed, J D. Connor, H Rasheed, A H. Gilani, S Lodhi, S S. Ali, S Rashid, E Khan, and B H. Shah

An investigation of cyclooxygenase and signalling inhibitors on 5-hydroxytryptamine- and epinephrine-induced platelet activation, S A. Saeed, H Rasheed, A H. Gilani, A Hashmi, and B H. Shah

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Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine, B H. Shah, H Rasheed, I H. Rahman, A H. Shariff, F L. Khan, H B. Rahman, S Hanif, and S A. Saeed

Submissions from 2000

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DDRT-PCR: Use of agarose gels for detection of amplified products, N Ahmed, Anwar Ali Siddiqui, and A Ahmed

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Vitamin E and beta-carotene affect natural killer cell function, M K. Ashfaq, H S. Zuberi, and Waqar M. Anwar

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Pharmacological basis for the use of peach leaves in constipation, A H. Gilani, N Aziz, S M. Ali, and M Saeed

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Ethnopharmacological evaluation of the anticonvulsant, sedative and antispasmodic activities of Lavandula stoechas L, A H. Gilani, N Aziz, M A. Khan, F Shaheen, Q Jabeen, B S. Siddiqui, and J W. Herzig

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The presence of cholinomimetic and calcium channel antagonist constituents in Piper betle Linn, A H. Gilani, N Aziz, I M. Khurram, Z A. Rao, and N K. Ali

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Hypotensive action of coumarin glycosides from Daucus carota, A H. Gilani, E Shaheen, S A. Saeed, S Bibi, Irfanullah, M Sadiq, and S Faizi

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Increased levels of multiple forms of dihydrofolate reductase in peripheral blood leucocytes of cancer patients receiving haematopoietic colony-stimulating factors: Interim analysis, M P. Iqbal, I A. Burney, F Sultana, N Mehboobali, and T Siddiqui

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An endogenous inhibitor of Ca++-ATPase from human placenta, M U. Javed, T Naru, and F Michelangeli

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Synergistic interaction of adrenaline and histamine in human platelet aggregation is mediated through activation of phospholipase, map kinase and cyclo-oxygenase pathways, B H. Shah, I Lashari, S Rana, O Saeed, H Rasheed, and S Arshad Saeed