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Submissions from 2005

G-protein beta-3 subunit gene 825C>T dimorphism is associated with left ventricular hypertrophy but not essential hypertension, M Saeed Mahmood, Zainul Sajadeen Urfy Mian, Atif Afzal, and Philippe M. Frossard

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Reliability of rodent animal models in biomedical research, Dileep Kumar Rohra, Ali Jawaid, Tauseef-ur-Rehman, and Ali Hyder Zaidi

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Biochemical screening for the prediction of preeclampsia, Dileep Kumar Rohra and Nazia Qidwai

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Acidosis-induced relaxation of human internal mammary artery is due to activation of ATP-sensitive potassium channels, Dileep Kumar Rohra, Hasanat Mohammad Sharif, Hina Saeed Zubairi, Kiran Sarfraz, Muhammad Nabeel Ghayur, and Anwarul Hassan Gilani

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Association of angiotensin converting enzyme gene polymorphisms with left ventricular hypertrophy, Mohammad Saeed, Danish Saleheen, Sammer Siddiqui, Aisha Khan, Zahid A. Butt, and Philippe M. Frossard

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Association of ACE polymorphisms with left ventricular hypertrophy, Mohammad Saeed, Sammer Siddiqui, Aisha Khan, Zahid A. Butt, S Hasan Parvez, and Philippe M. Frossard

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Fractals analysis of cardiac arrhythmias, Mohammed Saeed

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ABCA1, ApoA-I and type II DM, Danish Saleheen

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The "eye of the tiger" sign, Danish Saleheen, Philippe Frossard, Mahammed Zeeshan Ozair, Mohammad Ali Kazmi, Hamza Khalid, and Bhojo Khealani

Submissions from 2004

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Presence of cholinomimetic and acetylcholinesterase inhibitory constituents in betel nut, Anwar H. Gilani, M Nabeel Ghayur, Zafar S. Saify, Shahida P. Ahmed, M Iqbal Choudhary, and Asaad Khalid

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Pharmacological basis for the gut stimulatory activity of Raphanus sativus leaves, Anwarul Hassan Gilani and M Nabeel Ghayur

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Core concepts in biochemistry and molecular biology in an integrated MBBS curriculum, M P. Iqbal

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Myoglobin--a marker of reperfusion and a prognostic indicator in patients with acute myocardial infarction, M Perwaiz Iqbal, Khawar A. Kazmi, Naseema Mehboobali, and Abdul Rahbar

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Association study of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with myocardial infarction, M Perwaiz Iqbal, Saeed Mahmood, Naseema Mehboobali, Mohammad Ishaq, Tasnim Fatima, Saddiqa Parveen, and Philippe Frossard

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Increased levels of erythrocyte glutathione in acute myocardial infarction: An antioxidant defence, M P. Iqbal, M Ishaq, and N Mehboobali

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Variability in lipid profile in patients with acute myocardial infarction from two tertiary care hospitals in Pakistan, M P. Iqbal, M Shafiq, N Mehboobali, S P. Iqbal, and K Abbasi

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Head and neck cancer susceptibility: a genetic marker in the methylenetetrahydrofolate reductase gene, Nelofar Kureshi, Shehzad Ghaffar, Sammer Siddiqui, Iftikhar Salahuddin, and Philippe M. Frossard

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Gene markers and complex disorders: A review, M S. Mahmood, N Kureshi, and P M. Frossard

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Invasive aspergillosis with polyarthritis, S F. Mekan, O Saeed, and J A. Khan

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Involvement of thromboxane A2 and tyrosine kinase in the synergistic interaction of platelet activating factor and calcium ionophore A23187 in human platelet aggregation, Huma Rasheed and Sheikh Arshad Saeed

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Immunity in medicine, M Saeed

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A closer look at food allergy and intolerance, Sheikh Arshad Saeed, Rahmat Ali, Saad Shahid Ali, Nabeel Ahmad, Abdul Basit, and Mian Zainul Urfy

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Signaling mechanisms mediated by G-protein coupled receptors in human platelets, Sheikh Arshad Saeed, Huma Rasheed, Faisal A Wahed Fecto, Mohammad Ilyas Achakzai, Rahmat Ali, John Dennis Connor, and Anwar-ul-Hassan Gilani

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CAD risk factors and acute myocardial infarction in Pakistan, Danish Saleheen and Philippe Frossard

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5-HT7 receptor subtype as a mediator of the serotonergic regulation of luteinizing hormone release in the zona incerta, Arif Siddiqui, Mahmoud Abu-Amara, Cyrielle Aldairy, James J. Hagan, and Catherine Wilson

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Molecular identity, expression and functional analysis of interleukin-1alpha and its isoforms in rat testis, T Sultana, K V. Svechnikov, K Gustafsson, A Wahlgren, E Tham, G Weber, and O Soder

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Cystic breast lymphangioma, S N. Waqar, H Khan, S F. Mekan, N Kayani, and A J. Raja

Hepatitis C Virus persistence, virus and host related factors, Anila Yasmeen

Submissions from 2003

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Renal cortical necrosis: A case series of nine patients & review of literature, Syed Sohail Ali, Syed Zulfiqar Rizvi, Suhail Muzaffar, Aasim Ahmad, Akhtar Ali, and Sheema H. Hassan

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Cardiac acceleration as a marker of vagal withdrawal in heart rate control during exercise in humans, S S I Bokhari, H R. Ahmad, M M F Subhan, S A. Ali, and M N. Khan

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N-acetyl-beta-D-glucosaminidase in acute myocardial infarction, M Perwaiz Iqbal, Khawar A. Kazmi, Hasan R. Jafri, and Naseema Mehboobali

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Methylene tetrahydrofolate reductase gene and coronary artery disease, M P. Iqbal and P M. Frossard

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Effect of methotrexate and folinic acid on accumulation of iron in mice, M P. Iqbal, N Mehboobali, F Sultana, F B. Khan, I A. Burney, and G N. Kakepoto

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Enzymatic method for assaying calcium in serum with Ca++ -ATPase, Masood-ul-Hassan Javed and Francesco Michelangeli

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Expression of G protein alpha subunits in the lateral wall of the rat cochlea, Khalid M. Khan, Noorjehan Sarfaraz, Sammer Siddiqui, Zainab A. Malik, and Zeenat Salim

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The in vivo antifungal activity of the aqueous extract from Nigella sativa seeds, M A U Khan, M K. Ashfaq, H S. Zuberi, M S. Mahmood, and A H. Gilani

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The in vitro effect of aqueous extract of Nigella sativa seeds on nitric oxide production, M Saeed Mahmood, A H. Gilani, Afsheen Khwaja, Ayesha Rashid, and M K. Ashfaq

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Blood lead levels during pregnancy and pregnancy outcome in Karachi women, A Rahman and A Hakeem

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Effects of changes in pH on the contractility of vascular smooth muscle, Dileep Kumar Rohra

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Association of the angiotensin-converting enzyme (ACE) gene G2350A dimorphism with essential hypertension, M Saeed Mahmood, K Saboohi, Ali S. Osman, A M. Bokhari, and P M. Frossard

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Calcium-dependent synergistic interaction of platelet activating factor and epinephrine in human platelet aggregation, Sheikh Arshad Saeed and Huma Rasheed

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Synergism interaction between arachidonic acid by 5-hydroxytryptamine in human platelet aggregation is mediated through multiple signalling pathways, Sheikh Arshad Saeed, Huma Rasheed, and Anwar-ul-Hassan Gilani

Submissions from 2002

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Kushta(s): unique herbo-mineral preparations used in South Asian traditional medicine, N Aziz, A H. Gilani, and M A. Rindh

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A study of five human cytokine genes in human essential hypertension, Philippe M. Frossard, Abha Gupta, Vera Pravica, Chris Perrey, Ian V. Hutchinson, and Miodrag L. Lukic

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Lead-associated deficits in stature, mental ability and behaviour in children in Karachi, Abdur Rahman, Erum Maqbool, and Hina S. Zuberi

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Lead levels in primary teeth of children in Karachi, Abdur Rahman and Farzana Abubakar Yousuf

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Establishing clinical pharmacy services in a Pakistani intensive care unit, Zaidi Syed Tabish Razi, Sheikh Abdul Latif, and Raza Syed Shamim

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Plasma from rheumatoid patients taking low dose methotrexate enhances platelet aggregation, S A. Saeed, A H. Gilani, H Rasheed, F N. Bhatti, M Atiq, A Qureshi, R Jafary, and J D. Connor

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Latent activity of curcumin against leishmaniasis in vitro, Danish Saleheen, Syed Atif Ali, Khalid Ashfaq, Anwar Ali Siddiqui, Ajmal Agha, and Muhammad Masoom Yasinzai

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Determination of Alpha-i Antitrypsin Genetic Deficiency in Duodenal Ulcer by Polymerase Chain Reaction, A Shahid, H Qureshi, S J. Zuberi, Anwar Ali Siddiqui, T Sultana, and M A. Waqar

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Hepatitis E virus superinfection in patients with chronic liver disease, Hamid SS; Atiq M; Shehzad F; Yasmeen A,; Nissa T; Salam A; Anwar Ali Siddiqui; and Jafri W

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Unilateral gynaecomastia--an unusual presentation of thyrotoxicosis, S Tauheed and M N. Haque

Submissions from 2001

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Intercept shift in the breathlessness/ventilation relationship in response to progressive increase in workload: change in exercise breathlessness response, H R. Ahmad, M M. Subhan, S Bokhari, A Ali, and M N. Khan

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Second messengers in platelet aggregation evoked by serotonin and A23187, a calcium ionophore, J D. Connor, H Rasheed, A H. Gilani, M Cheema, Z Rizvi, and S A. Saeed

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Bronchodilator, spasmolytic and calcium antagonist activities of Nigella sativa seeds (Kalonji): a traditional herbal product with multiple medicinal uses, A H. Gilani, N Aziz, I M. Khurram, K S. Chaudhary, and A Iqbal

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Induction of white cell proliferation due to haematopoietic growth factors is associated with an increase in multiple forms of dihydrofolate reductase in non-neutropenic cancer patients, M P. Iqbal, I A. Burney, F Sultana, and N Mehboobali

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Folinic acid protects against suppression of growth by Methotrexate in mice, M. Perwaiz Iqbal, Fakhara Sultana, Naseema Mehboobali, and Shahid Pervez

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An enzymatic method for the detection of human serum albumin, M U. Javed and S N. Waqar

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Problem-based learning variant: Transition phase for a large institution, I Khan and A Fareed

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Nitric oxide mediated effect of cyclo-oxygenase inhibitors, M Mahmood, H S. Zuberi, and M K. Ashfaq

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New vistas in the therapeutic uses of aspirin, S. A. Saeed, M Atiq, Salim S. Virani, and A. H. Gilani

Wortmannin inhibits platelet aggregation produced by interaction of gamma-aminobutyric acid and the calcium tonophore, A23187, S A. Saeed, J D. Connor, H Rasheed, A H. Gilani, S Lodhi, S S. Ali, S Rashid, E Khan, and B H. Shah

An investigation of cyclooxygenase and signalling inhibitors on 5-hydroxytryptamine- and epinephrine-induced platelet activation, S A. Saeed, H Rasheed, A H. Gilani, A Hashmi, and B H. Shah

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Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine, B H. Shah, H Rasheed, I H. Rahman, A H. Shariff, F L. Khan, H B. Rahman, S Hanif, and S A. Saeed

Submissions from 2000

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DDRT-PCR: Use of agarose gels for detection of amplified products, N Ahmed, Anwar Ali Siddiqui, and A Ahmed

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Vitamin E and beta-carotene affect natural killer cell function, M K. Ashfaq, H S. Zuberi, and Waqar M. Anwar

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Pharmacological basis for the use of peach leaves in constipation, A H. Gilani, N Aziz, S M. Ali, and M Saeed

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Ethnopharmacological evaluation of the anticonvulsant, sedative and antispasmodic activities of Lavandula stoechas L, A H. Gilani, N Aziz, M A. Khan, F Shaheen, Q Jabeen, B S. Siddiqui, and J W. Herzig

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The presence of cholinomimetic and calcium channel antagonist constituents in Piper betle Linn, A H. Gilani, N Aziz, I M. Khurram, Z A. Rao, and N K. Ali

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Hypotensive action of coumarin glycosides from Daucus carota, A H. Gilani, E Shaheen, S A. Saeed, S Bibi, Irfanullah, M Sadiq, and S Faizi

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Increased levels of multiple forms of dihydrofolate reductase in peripheral blood leucocytes of cancer patients receiving haematopoietic colony-stimulating factors: Interim analysis, M P. Iqbal, I A. Burney, F Sultana, N Mehboobali, and T Siddiqui

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An endogenous inhibitor of Ca++-ATPase from human placenta, M U. Javed, T Naru, and F Michelangeli

Effects of yoga on blood pressure levels in normotensive and hypertensive subjects /, Sheela Pinjani

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Synergistic interaction of adrenaline and histamine in human platelet aggregation is mediated through activation of phospholipase, map kinase and cyclo-oxygenase pathways, B H. Shah, I Lashari, S Rana, O Saeed, H Rasheed, and S Arshad Saeed

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Low serum alpha 1 antitrypsin in duodenal ulcer--a family study, Anjum Shahid; Sarwar J; Zuberi Mohammad A; Waqar,Huma Qureshi Waqar,Huma Qureshi Waqar,Huma Qureshi; Anwar Ali Siddiqui; and Taranum Sultana

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Phenotypes of Alpha 1 Antitrypsin in Karachi, Pakistan, Anjum Shahid, Anwar Ali Siddiqui, Sarwar i J. Zuberi, and Mohammad Waqar

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Serotonin inhibits luteinizing hormone release via 5-HT1A receptors in the zona incerta of ovariectomised, anaesthetised rats primed with steroids, A Siddiqui, K Kotecha, A M. Salicioni, V Kalia, J F. Murray, and C A. Wilson

Submissions from 1999

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Atherosclerosis and plaque rupture: An update, M N. Afzal, S A. Saeed, and B H. Shah

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Possible mechanism of selective inotropic activity of the n-butanolic fraction from Berberis aristata fruit, A H. Gilani, K H. Janbaz, N Aziz, M J. Herzig, M M. Kazmi, M I. Choudhary, and J W. Herzig

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Studies on antihypertensive and antispasmodic activities of methanol extract of Acacia nilotica pods, A H. Gilani, F Shaheen, M Zaman, K H. Janbaz, B H. Shah, and M S. Akhtar

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Additive effect of indomethacin and methotrexate on suppression of growth in rats, M P. Iqbal, S A. Saeed, S Pertani, and N Mehboobali

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Detection of lactate dehydrogenase isoenzyme-M in body fluids containing albumin, M H. Javed, A H. Jafri, and F A. Yousuf

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Effect of amino acids on inhibition of lactate dehydrogenase-X by gossypol, M H. Javed and M A. Khan

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GroEL protects the sarcoplasmic reticulum Ca(++)-dependent ATPase from inactivation in vitro, M U. Javed, F Michelangeli, and P A. Lund

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Ca2+ sensitization of myocardial force and actomyosin ATPase by (D-Ala2, Met5) enkephalinamide, H Loewe, I Baeger, A Knoll, and J W. Herzig

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Cholera toxin mediated regulation of the expression of Gq alpha and G11 alpha GTP binding proteins, B H. Shah

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Inhibitory effect of curcumin, a food spice from turmeric, on platelet-activating factor- and arachidonic acid-mediated platelet aggregation through inhibition of thromboxane formation and Ca2+ signaling, B H. Shah, Z Nawaz, S A. Pertani, A Roomi, H Mahmood, S A. Saeed, and A H. Gilani

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Co-activation of Gi and Gq proteins exerts synergistic effect on human platelet aggregation through activation of phospholipase C and Ca2+ signalling pathways, B H. Shah, A Siddiqui, K A. Qureshi, M Khan, S Rafi, V A. Ujan, M Y. Yakoob, Y Yaqub, H Rasheed, and S A. Saeed

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Physiology teaching in the developing world: models for quality learning, A Siddiqui

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Risk of transmission and features of hepatitis C after needlestick injuries., Hamid SS, Farooqui B, Rizvi Q, Sultana T, and Anwar Ali Ali Siddiqui

Submissions from 1998

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Esculetin prevents liver damage induced by paracetamol and CCL4, A H. Gilani, K H. Janbaz, and B H. Shah

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Accumulation of methotrexate in human tissues following high-dose methotrexate therapy, M P. Iqbal

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Urinary N-acetyl-beta-D-glucosaminidase in rheumatoid arthritis, M P. Iqbal, A A. Ali, M A. Waqar, and N Mehboobali

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The effects of non-steroidal anti-inflammatory drugs on the disposition of methotrexate in patients with rheumatoid arthritis, M P. Iqbal, J A. Baig, A A. Ali, S K. Niazi, N Mehboobali, and M A. Hussain

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A simple method for the detection of lactate dehydrogenase isoenzymes M:H ratio by gel filtration, M H. Javed and T Y. Naru

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Dual effects of nimesulide, a COX-2 inhibitor, in human platelets, S A. Saeed, M N. Afzal, and B H. Shah

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Myocardial ischaemia and infarction in isoprenaline-treated rabbits: role of cyclooxygenases, S A. Saeed, A H. Gilani, B H. Sultan, R M. Karim, and B H. Shah

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The inhibitory effect of cinchonine on human platelet aggregation due to blockade of calcium influx, Bukhtiar H. Shah, Zafar Nawaz, Salim S. Virani, Imran Q. Ali, S A. Saeed, and Anwar H. Gilani

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Cerebrospinal fluid proteins in meningitis, Anwar Ali Siddiqui, TAJBIBI Z. Ali, NASEEMA M. Ali, M KHURSHIDt, and MOHAMMAD A. WAQAR

Submissions from 1997

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Quercetin exhibits hepatoprotective activity in rats, A H. Gilani, K H. Janbaz, and B H. Shah