The Department of Internal Medicine is the largest department at Aga Khan University. Our Department is comprised of multiple sub-specialties with diverse faculty trained both locally and internationally. Our faculty, residents and staff at Aga Khan University, Nairobi are committed to ensuring top-notch patient-centered health care and patient safety, excellence in education and dedication to cutting-edge research.

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Submissions from 2014

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DSM‐5 and ICD‐11 definitions of posttraumatic stress disorder: Investigating “narrow” and “broad” approaches, Dan J. Stein, Katie A. McLaughlin, Karestan C. Koenen, Lukoye Atwoli, Matthew J. Friedman, Eric D. Hill, Andreas Maercker, Maria Petukhova, Victoria Shahly, and Mark van Ommeren

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Emerging antiretroviral drug resistance in sub-Saharan Africa: novel affordable technologies are needed to provide resistance testing for individual and public health benefits, Gert U. van Zyl, Lisa M. Frenkel, Michael Chung, Wolfgang Preiser, John W. Mellors, and Jean B. Nachega

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Acute management of ST-elevation myocardial infarction in a tertiary hospital in Kenya: are we complying with practice guidelines?, Benjamin Wachira, Andrew Owuor, and Harun Otieno

Submissions from 2013

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HIV-1 progression links with viral genetic variability and subtype, and patient’s HLA type: analysis of a Nairobi-Kenyan cohort, Syed Hani Abidi, Aniqa Shahid, Laila S. Lakhani, Reena Shah, Nancy Okinda, Peter Ojwang, Farhat Abbas, Sarah Rowland-Jones, and Syed Ali

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Breaking bad news in clinical setting - health professionals' experience and perceived competence in southwestern Nigeria: A cross sectional study, Philip Adebayo, Olukayode Abayomi, Peter O. Johnson, Taofeeq Oloyede, and Abimbola A. Oyelekan

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Neuropsychiatric and Parkinsonian manifestations of dementia: A case report in a Nigerian woman, Philip Adebayo, Ajan A. Ajani, Olaleye A. Adenij, and Rufus O. Akinyemi

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Anthropometric differences among natives of Abuja living in urban and rural communities: correlations with other cardiovascular risk factors, Olufemi Sola Adediran, Philip Adebayo, and Adeseye Abiodun Akintunde

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Carotid atherosclerosis and right ventricular diastolic dysfunction in a sample of hypertensive Nigerian patients, Adeseye A. Akintunde, Philip Adebayo, Ademola A. Aremu, and Oladimeji G. Opadijo

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Trauma and posttraumatic stress disorder in South Africa: analysis from the South African Stress and Health Study, Lukoye Atwoli, Dan J. Stein, David R. Williams, Katie A. Mclaughlin, Maria Petukhova, Ronald C. Kessler, and Karestan C. Koenen

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Comparing Papanicolau smear, visual inspection with acetic acid and human papillomavirus cervical cancer screening methods among HIV-positive women by immune status and antiretroviral therapy, Michael Chung, K. P. McKenzie, H. D. Vuyst, B. A. Richardson, Farzana Rana, R. Pamnani, J. W. Njoroge, E. Nyongesa-Malava, S. R. Sakr, G. C. John-Stewart, and N. R. Mugo

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The journey of addiction: Barriers to and facilitators of drug use cessation among street children and youths in Western Kenya, Lonnie Embleton, Lukoye Atwoli, David Ayuku, and Paula Braitstein

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Harnessing the power of the grassroots to conduct public health research in sub-Saharan Africa: a case study from western Kenya in the adaptation of community-based participatory research (CBPR) approaches, Allan Kamanda, Lonnie Embleton, David Ayuku, Lukoye Atwoli, Peter Gisore, Samuel Ayaya, Rachel Vreeman, and Paula Braitstein

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Effect of mobile phone short message service on adherence rates to antihypertensives at the Family Medicine Clinic, Barbara Karau

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The muranga teleophthalmology study: comparison of virtual (teleglaucoma) with in-person clinical assessment to diagnose glaucoma, Dan Kiage, Irfan N. Kherani, Stephen Gichuhi, Karim F. Damji, and Muindi Nyenze

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Prevalence and factors associated with depression among patients with epilepsy in a Kenyan tertiary care hospital, Nduku Kiko

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Substance use among inmates at the Eldoret prison in Western Kenya, Daniel WC Kinyanjui and Lukoye Atwoli

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Improving diabetic retinopathy screening in Africa: Patient satisfaction with teleophthalmology versus ophthalmologist-based screening, K. Kurji, D. Kiage, C. J. Rudnisky, and K. F. Damji

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The prevalence of post-traumatic stress disorder among sexually abused children at kenyatta national hospital in Nairobi, Kenya, C. A. OMBOK, A. Obondo, and Lukoye Atwoli

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Clinical characteristics and outcomes of atrial fibrillation and flutter at the Aga Khan University Hospital, Nairobi, Jay Shavadia, Gerald Yonga, Sitna Mwanzi, Ashna Jinah, Abednego Moriasi, and Harun Otieno

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Readmission and death after an acute heart failure event: predictors and outcomes in sub-saharan africa: results from the thesus-hf registry, K. Sliwa, B. A. Davison, B. M. Mayosi, A. Damasceno, M. Sani, O. S. Ogah, C. Mondo, D. Ojji, A. Dzudie, C. K. Kouam, A. Suliman, N. Schrueder, Gerald Yonga, S. A. Ba, F. Maru, B. Alemayehu, C. Edwards, and G. Cotter

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Major incidents in Kenya: the case for emergency services development and training, Benjamin Wachira and Wayne Smith

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The prevalence of smoking and the knowledge of smoking hazards and smoking cessation strategies among hiv positive patients in johannesburg, south africa, Peter Waweru, R. Anderson, H. Steel, WDF. Venter, D. Murdoch, and C. Feldman

Submissions from 2012

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Short-term diagnostic stability among re-admitted psychiatric in-patients in Eldoret, Kenya, Lukoye Atwoli, D. Ndambuki, P. OWITI, G. Manguro, and N. Omulimi

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The causes, treatment, and outcome of acute heart failure in 1006 Africans From 9 countries, Albertino Damasceno, Bongani M. Mayosi, Mahmoud Sani, Okechukwu S. Ogah, Charles Mondo, Dike Ojji, Anastase Dzudie, Charles Kouam Kouam, Ahmed Suliman, Neshaad Schrueder, Gerald Yonga, Serigne Abdou Ba, Fikru Maru, Bekele Alemayehu, Christopher Edwards, Beth A. Davison, Gad Cotter, and Karen Sliwa

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The use of bevacizumab among women with metastatic breast cancer: a survey on clinical practice and the ongoing controversy., Shaheenah Dawood, Asim Jamal, Thomas A. Buchholz, Javier Cortes, Massimo Cristofanilli, Sudeep Gupta, and Ana M. Gonzalez‐Angulo

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Knowledge, attitudes, and substance use practices among street children in Western Kenya, Lonnie Embleton, David Ayuku, Lukoye Atwoli, Rachel Vreeman, and Paula Braitstein

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Risk of restless legs syndrome in low socioeconomic rheumatoidarthritis patients, Muhammad Ishaq, Jibran Sualeh Muhammad, and Kamran Hamid

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Adjuvant Hormonal Therapy in Postmenopausal Women with Breast Cancer: Physician's Choices, Asi Jamal, Shiyam Kumar, Sajjad Raza, Maria Mehboob, and Osama Ishtiaq

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Molecular Targeting Agents in Cancer Therapy: Science and Society, Asim Jamal

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Psychiatric morbidity among HIV-infected children and adolescents in a resource-poor Kenyan urban community, Judy W. Kamau, Wangari Kuria, Muthoni Mathai, Lukoye Atwoli, and Rachael Kangethe

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Preoperative medical consultation: maximizing its benefits, Raul A, Rivera; Nguyen T. Mai; Jorge I. Martinez-Osorio; Matthew F, McNeill; Sayed Karar; and Ishak A Mansi A. Mansi

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A prospective review of acute coronary syndromes in an urban hospital in sub-Saharan Africa, Jay Shavadia, Gerald Yonga, and Harun Otieno

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The influence of antiretroviral therapy on the QTc interval in an African cohort, J. Shavadia, Reena Shah, Gerald Yonga, R. Patel, J. Stebbing, and M. Nelson

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Community perspectives on research consent involving vulnerable children in Western Kenya, Rachel Vreeman, Eunice Kamaara, Allan Kamanda, David Ayuku, Winstone Nyandiko, Lukoye Atwoli, Samuel Ayaya, Peter Gisore, Michael Scanlon, and Paula Braitstein

Submissions from 2011

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Postpartum Depression, Lukoye Atwoli

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Prevalence of substance use among college students in Eldoret, western Kenya, Lukoye Atwoli, Prisca A. Mungla, Moses N. Ndung'u, Kiende C. Kinoti, and Evans M. Ogot

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Attention deficit hyperactivity disorder symptom self-report among medical students in Eldoret, Kenya, Lukoye Atwoli, P. Owiti, G. Manguro, and D. NDAMBUKI

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Hepatitis B vaccination rate and determining factors amongst health care workers at Aga Khan University Hospital, Nairobi, Herman Ekea

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Comparison of Complete Versus Incomplete Stent Frame Expansion After Transcatheter Aortic Valve Implantation With Medtronic Coke Valve Bioprosthesis, Hasan Jilaihawi, Derek Chin, Tomasz J. Spyt, Jeilan Mohamed, Mariuca Vasa-Nicotera, Noor Mohamed, Johan Bence, Elaine Logtens, and Jan Kovac

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The influence of depression on adherence to antiretroviral therapy among HIV infected patients at Aga Khan University Hospital (Nairobi), Evelyn W. Karanja-Mbugua

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Cytological diagnosis of typical carcinoid on bronchoscopic brush smears in an HIV-positive patient, Neeta Kumar, Shahin Sayed, and Swati Das

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159 Pilot Study exploring the regional repolarisation instability index in relation to myocardial heterogeneity and prediction of ventricular arrhythmia and death, William B. Nicolson, Christopher D. Steadman, P. Brown, Jeilan Mohamed, S. Yusuf, S Kundu, A. J. Sandilands, P. J. Stafford, F. S. Schlindwein, G. P. McCann, and G. Andre Ng

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Regional fractionation and dominant frequency in persistent atrial fibrillation: effects of left atrial ablation and evidence of spatial relationship, Jiun Tuan, Jeilan Mohamed, Suman Kundu, Will Nicolson, Irene Chung, Peter J. Stafford, and G. André Ng

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An analysis of the clinical practice of emergency medicine in public emergency centres in Kenya, Benjamin W. Wachira

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Outbreak of beriberi among African union troops in Mogadishu, Somalia, John T. Watson, Hassan El Bushra, Emmaculate J. Lebo, Godfrey Bwire, James Kiyengo, Gideon Emukule, Victor Omballa, John Tole, Muvunyi Zuberi, Robert F. Breiman, and Mark A. Katz

Submissions from 2010

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Emergency mental health and psychosocial support for survivors of post-election violence in Eldoret, Kenya, Lukoye Atwoli

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Self-reported Attention Deficit and Hyperactivity Disorder symptoms among university students in Eldoret, Kenya, Lukoye Atwoli, P. Owiti, G. Manguro, and D. NDAMBUKI

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Prosthesis-patient mismatch after transcatheter aortic valve implantation with the Medtronic-Corevalve bioprosthesis, Hasan Jilaihawi, Derek Chin, Tomasz Spyt, Jeilan Mohamed, Mariuca Vasa-Nicotera, Johan Bence, Elaine Logtens, and Jan Kovac

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Peripheral arterial disease in HIV positive and negative subjects at The Aga Khan University Hospital, Nairobi, Farida Kaittany

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Familial clustering of cancer in two tertiary care hospitals in Nairobi, Kenya, G. W. Kiarie, N. O. Abinya, M. D. Joshi, G. N. Lule, and G. Z. Mutuma

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Influence of patient's perceptions, beliefs and knowledge about cancer on treatment decision making in Pakistan, Shiyam Kumar, Asim Jamal, Sana Khalid, and Nehal Masood

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Striking electrical and mechanical alternans associated with cardiac tamponade., Jeilan Mohamed, Abubakar Habib, Helen Colver, Suman Kundu, Noor Mohammed, and Ian Loke

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Ganglionic plexus ablation during pulmonary vein isolation--predisposing to ventricular arrhythmias?, Faizel Osman, Suman Kundu, Jiun Tuan, Jeilan Mohamed, Peter J. Stafford, and G. Andre' Ng

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A randomised comparative trial of seven versus fourteen day triple therapy for helicobacter pylori eradication at The Aga Khan University Hospital, Nairobi, Ahmed Sokwala

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Increase in organization index predicts atrial fibrillation termination with flecainide post-ablation: spectral analysis of intracardiac electrograms, Jiun Tuan, Faizel Osman, Jeilan Mohamed, Suman Kundu, Rajkumar Mantravadi, Peter J. Stafford, and G. André Ng

Submissions from 2009

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ACE-I induced angioedema: a case report and review of literature, Philip Adebayo and Olutayo Christopher Alebiosu

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Neuroleptic induced tardive dyskinesa in a patient on treatment for schizophrenia: a case report, Lukoye Atwoli, G. MANGURO, P. OWITI, and D. NDAMBUKI

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Predictors for permanent pacemaker requirement after transcatheter aortic valve implantation with the CoreValve bioprosthesi, Hasan Jilaihawi, Derek Chin, Mariuca Vasa-Nicotera, Jeilan Mohamed, Tomasz Spyt, G. Andre' Ng, Johan Bence, Elaine Logtens, and Jan Kovac

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Early regression of left ventricular wall thickness following percutaneous aortic valve replacement with the CoreValve bioprosthesis., Hasan Jilaihawi, Jeilan Mohamed, Tomasz Spyt, Derek Chin, Elaine Logtens, and Jan Kovac

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The univariate and bivariate impact of HIV/AIDS on the quality of life: A cross sectional study in the Hubei Province-Central China, Omari Baaliy Mkangara; Chongjian Wang; Hao Xiang; Yihua Xu,; Shaofa Nie; Li Liu; Saumu Tobbi Mweri; Mustaafa Bapumia; Theresia M. Kobelo; and Felicia Williams Jackson

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Letter by Jeilan et al regarding article, "Longitudinal strain delay index by speckle tracking imaging: a new marker of response to cardiac resynchronization therapy"., Jeilan Mohamed, Jiun H. Tuan, and G. Andre' Ng

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Risk of contrast induced nephropathy in HIV patients receiving radiographic contrast at three Aga Khan Hospitals, Sitna A. Mwanzi

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Evaluation of atrial septal defect using real-time three-dimensional echocardiography: Comparison with surgical findings, Saumu Tobbi Mweri, Youbin Deng, eixuan Cheng, Hanhua Lin, Hongwei Wang, Ommari Baaliy Mkangara, Zhi Xia, Xiufen Hu, Xiaojun Bi, Yuhan Wu, Mustaafa Bapumia, Weihui Shentu, Rong Liu, Yani Li, and Meihua Zhu

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Use of triple-site ventricular pacing in a patient with severe congestive heart failure and atrial fibrillation., Faizel Osman, Jeilan Mohamed, and G. Andre' Ng

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Antiretroviral therapy dose adjustments based on calculated creatinine clearance, J. Shavadia, G. Tesfaldet, and Majid Twahir

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Relationship between the spectral characteristics of atrial fibrillation and atrial tachycardias that occur after catheter ablation of atrial fibrillation, Jiun Tuan, Jeilan Mohamed, Suman Kundu, and G. Andre' Ng

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Pulmonary Vein Isolation using a High Density Mesh Ablator Catheter: Incorporation of three-Dimensional Navigation and Mappin, Jiun Tuan, Jeilan Mohamed, Faizel Osman, Suman Kundu, Rajkumar Mantravadi, Peter J. Stafford, and G. André Ng

Submissions from 2008

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Primary cerebral angitis of the central nervous system: case report, S. Das, J. O. Jowi, K. Hameed, and F. S. Rana

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Pathological sub-types, risk factors and outcome of stroke at the Nairobi hospital, Kenya, James Jowi and Peter Mativo

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A review of electroencephalograms done at the Kenyatta National Hospital, Nairobi, J. O. Jowi, Z. P Kidiga, and M. G. Gitau

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Fanconi Syndrome and Lactic Acidosis Associated with Stavudine and Lamivudine Therapy. AIDS., Nelson, Mark; Azwa, Alex; Ahmed Sokwala; Reena Shah; and Stebbing, Justin

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The concept of skin bleaching in Africa and its devastating health implications, Melanie Miyanji

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Epidemiology of human immuno-deficiency virus and quality of life for people living with HIV/AIDS in China, Ommari Baaliy Mkangara, Shaofa Nie, Chongjian Wang, Yihua Xu, Saumu Tobbi Mweri, Theresia M. Kobelo, and Mustaafa Bapumia

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Re: The atrioventricular delay of cardiac resynchronization can be optimized hemodynamically during exercise and predicted from resting measurements., Jeilan Mohamed, Suman Kundu, Jiun H. Tuan, and G. Andre Ng

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Images in cardiovascular medicine. Cardiac tuberculoma., Jeilan Mohamed, Matthias Schmitt, Gerry McCann, Joan Davies, Joseph Leverment, and Derek Chin

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Prevalence, risk factors and outcome of acute kidney injury at the Aga Khan University Hospital Nairobi, Peter W. Munyu

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A randomised comparative clinical trial of prokinetic agents and proton pump inhibitors in H. pylori negative non-ulcer dyspepsia, Mzee Ngunga

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Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes, Paul J. Norman, Laurent Abi-Rached, Ketevan Gendzekhadze, John A. Hammond, Achim K. Moesta, Deepti Sharma, Thorsten Grief, Karina L. McQueen, Lisbeth A. Guethlein, and Kamran Ahmed

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HIV, hepatitis B and hepatitis C coinfection in Kenya, Reena Shah, Jane Karuru, Mark Nelson, and Justin Stebbing

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HIV-Associated pulmonary hypertension: case report, Jay Shavadia, S. Das, and Gerald Yonga

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A randomized controlled trial testing the efficacy of an HIV/AIDS symptom management manual, Dean J. Wantland, William L. Holzemer, Shahnaz Moezzi, Suzanne S. Willard, John Arudo, Kenn M. Kirksey, Carmen J. Portillo, Inge B. Corless, Marı´a E. Rosa, Linda L. Robinson, Patrice K. Nicholas, Mary Jane Hamilton, Elizabeth F. Sefcik, Sarie Human, Marta M. Rivero, Mary Maryland, and Emily Huang

Submissions from 2007

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An Afternoon in Iraq, Sayed Karar

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Transvenous pacing causing tamponade in patients receiving glycoprotein IIb/IIIa inhibitors for percutaneous coronary intervention, Jeilan Mohamed, Gail Richardson, and Anthony Gershlick

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Osmotic demyelination syndrome: Case report, Mzee Ngunga, R. Harania, K. Hameed, and J. O. Jowi

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Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans, Paul J. Norman, Laurent Abi-Rached, Ketevan Gendzekhadze, Daniel Korbel, Michael Gleimer, Don Rowley, Dan Bruno, Christine V F Carrington, Dasdayanee Chandanayingyong, and Kamran Hamid

Submissions from 2006

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HLA‐DQB1 locus and gastric cancer in Helicobacter pylori infection, Yoshinori Watanabe, Nobuo Aoyama, Toshiyuki Sakai, Daisuke Shirasaka, Shuji Maekawa, Kohei Kuroda, Casmir Wambura, Takao Tamura, Yoshisuke Nose, and Masato Kasuga

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Using UMLS metathesaurus concepts to describe medical images: dermatology vocabulary, James W. Woods, Charles A. Sneiderman, Kamran Hamid, Michael J. .Ackerman, and Charlie Hatton

Submissions from 2005

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Characteristics and outcome of chest pain in young adults., Muhammad Shahid and Kamran Hameed

Submissions from 2004

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SNP haplotypes and allele frequencies show evidence for disruptive and balancing selection in the human leukocyte receptor complex, Paulo j. Norman; Mark A. Cook; B. Sean Carey; Christine V.F Carrington; David H. Verity; Kamran Hamid; D. Dan Ramdath; Dasnayanee Chandanayingyong,; Mark Leppert,; Henry A.F Stephens; and R. W. R.W Vaughan

Submissions from 2003

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Impact of clarithromycin resistance and CYP2C19 genetic polymorphism on treatment efficacy of Helicobacter pylori infection with lansoprazole- or rabeprazole-based triple therapy in Japan, Miki Ikuya, Aoyama Nobuo, Sakai Toshiyuki, Shirasaka Daisuke, Casmir Wambura, Maekawa Shujia, Kuroda Kohei, Tamura Takao, Kita Tomoko, Sakaeda Toshiyuki, Katsuhiko Okumura, and Kasuga Masato

Submissions from 2002

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Relationship Between Gastric Ulcer and Helicobacter pylori VacA Detected in Gastric Juice Using Bead-ELISA Method, Daisuke Shirasaka, Nobuo Aoyama, Masanori Sakashita, Kohei Kuroda, Casmir Wambura, Masaki Miyamoto, Takao Tamura, Kinnosuke Yahiro, Akihiro Wada, and Hisao Kurazono

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Effect of Helicobacter pylori‐Induced Cyclooxygenase‐2 on Gastric Epithelial Cell Kinetics: Implication for Gastric Carcinogenesis, Casmir Wambura, Nobuo Aoyama, Daisuke Shirasaka, Toshiyuki Sakai, Takahiro Ikemura, Masanori Sakashita, Shuji Maekawa, Kohei Kuroda, Takashi Inoue, Shigeyuki Ebara, Masaki Miyamoto, and Masato Kasuga

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Nephropathy in patients with recently diagnosed type 2 diabetes mellitus black Africans, F. W. Wanjohi, F. C. F. Otieno, E. N. Ogola, and E. O. Amayo

Submissions from 1999

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Cardiovascular autonomic neuropathy in HIV infected patients, Karen E. Rogstad, Reena Shah, G. Tesfaladet, Mohammed Abdullah, and Imtyaz Ahmed-Jushuf