The Department of Internal Medicine is the largest department at Aga Khan University. Our Department is comprised of multiple sub-specialties with diverse faculty trained both locally and internationally. Our faculty, residents and staff at Aga Khan University, Nairobi are committed to ensuring top-notch patient-centered health care and patient safety, excellence in education and dedication to cutting-edge research.

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Submissions from 2016

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Diagnostic Accuracy of Ultrasound B scan using 10 MHz linear probe in ocular trauma;results from a high burden country, Muhammad KashifShazlee, Muhammad Ali, Muhammad Saad Ahmed, Ammad Hussain, Kamran Hameed, Irfan Amjad Lutfi, and Muhammad Tahir Khan

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Renal dysfunction among adult patients in Mwanza, Tanzania: prevalence, outcomes and associated factors, Semvua B. Kilonzo, Abdulraassul T. Seiffudin, Fatma Bakshi, and Daniel W. Gunda

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A case of refractory thrombotic thrombocytopenic purpura treated with plasmapheresis and rituximab, Nicholas Kirui and Ahmed Sokwala

Risk factors, Clinico-Pathologic Characteristics and Outcomes in Young Kenyan Female Patients with Breast Cancer in AKUH-N, Gilford Mutwiri Mwikamba

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What change in outcomes after cardiac arrest is necessary to change practice? Results of an international survey, Graham Nichol, Siobhan P. Brown, Gavin D. Perkins, Francis Kim, Fritz Sterz, Jo Ann Broeckel Elrod, Spyros Mentzelopoulos, Richard Lyon, Yaseen Arabi, Maaret Castren, Peter Larsen, Terence Valenzuela, Jan-Thorsten Graesner, Scott Youngquist, Nalinas Khunkhlai, Henry E. Wang, Franek Ondrej, Juan Manuel Fraga Sastrias, Anders Barasa, and Michael R. Sayre

Factors that Influence Advance Directives Completion amongst Terminally Ill Patients at AKUHN, Stephen Omondi Otieno

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Simplified Paper Format for Detecting HIV Drug Resistance in Clinical Specimens by Oligonucleotide Ligation, Nuttada Panpradist, Ingrid A. Beck, Michael Chung, James N. Kiarie, Lisa M. Frenkel, and Barry R. Lutz

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Symptoms in women with Peripartum Cardiomyopathy: A mixed method study, Harshida Patel, Marie Berg, Anders Barasa, Cecily Begley, and Maria Schaufelberger

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Clinical care of incarcerated people with HIV, viral hepatitis, or tuberculosis, Josiah D. Rich, Curt G. Beckwith, Alexandria Macmadu, Brandon D L Marshall, Lauren Brinkley-Rubinstein, Joseph J. Amon, M-J Milloy, Maximilian R F King, Jorge Sanchez, and Lukoye Atwoli

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Epilepsy Prevalence, Treatment Gap, and Stigma in Western Kenya (P1.272), Dilraj Sokhi, Monica Diaz, Anthony Ngugi, Tom Solomon, Eric Fevre, and Anna-Claire Meyer

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Post-traumatic stress disorder associated with life-threatening motor vehicle collisions in the WHO World Mental Health Surveys, Dan J. Stein, Elie G. Karam, Victoria Shahly, Eric D. Hill, Andrew King, Maria Petukhova, Lukoye Atwoli, Evelyn J. Bromet, Silvia Florescu, and Josep Maria Haro

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Partner Disclosure and Early CD4 Response among HIV-Infected Adults Initiating Antiretroviral Treatment in Nairobi Kenya, T. Tony Trinh, Nelly Yatich, Richard Ngomoa, Christine J. McGrath, Barbra A. Richardson, Samah R. Sakr, Agnes Langat, Grace C. John-Stewart, and Michael Chung

Outcomes in Patients with Acute Coronary Syndromes at The Aga Khan University Hospital, Nairobi, Mohamed Hasham Varwani

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Telephone versus Face to Face Palliative Care Consults during Referral, John Weru

Submissions from 2015

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The Prevalence, Risk Factors and Changes in Symptoms of Self Reported Asthma, Rhinitis and Eczema Among Pregnant Women in Ogbomoso, Nigeria, Adewale Samson Adeyemi,; Adeolu Oladayo Akinboro; Philip Adebayo; Moses O. Tanimowo; and Olugbenga Edward Ayodele

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Task-shifting training improves stroke knowledge among Nigerian non-neurologist health workers, Rufus O. Akinyemi, Mayowa O. Owolabi, Philip Adebayo, Joshua O. Akinyemi, and Folajimi M. Otubogun

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Association between witnessing traumatic events and psychopathology in the South African Stress and Health Study, Lukoye Atwoli, Jonathan Platt, David R. Williams, Dan J. Stein, and Karestan C. Koenen

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Epidemiology of posttraumatic stress disorder: prevalence, correlates and consequences, Lukoye Atwoli, Dan Stein, Karestan C. Koenen, and Katie A. Mclaughlin

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Large scale genetic research on neuropsychiatric disorders in african populations is needed, Shareefa Dalvie, Nastassja Koen, Laramie Duncan, Catherine Abbo, Dickens Akena, Lukoye Atwoli, Bonginkosi Chiliza, Kirsten A. Donald, Eugene Kinyanda, and Christine Lochner

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Development of the roadmap and guidelines for the prevention and management of high blood pressure in Africa: Proceedings of the PASCAR: Hypertension task force meeting: Nairobi, Kenya, Anastase Dzudie, Dike Ojji, Benedict Chukwuemeka Anisiuba, Serigne Abdou, Ruth Cornick, Albertino Damasceno, Abdoul Kane, Ana Ogla Mocumbi, Awad Mohamed, George Nel, Elijah Ogola, Basden Onwubere, Harun Otieno, Brian Rainer, Aletta Schutte, Ibrahim Toure Ali, Marc Twagirumukiza, Neil Poulter, and Bongani Mayosi

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Pulmonary cryptococcosis presenting as acute severe respiratory distress in a newly diagnosed HIV patient in Tanzania: a case report, Gunda W. Gunda, Fatma Bakshi, Peter Rambau, and Semvua B. Kilonzo

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Methylation Levels of CADM1, MAL, and MIR124-2 in Cervical Scrapes for Triage of HIV-Infected, High-Risk HPV-Positive Women in Kenya., De Vuyst Hugo, Franceschi Silvia, Plummer Martyn, Nelly R. Mugo, Samah R. Sakr, Chris J. L. M. Meijer, Daniëlle A. M. Heideman, Vanessa Tenet, Peter J. F. Snijders, Albertus T. Hesselink, and Michael Chung

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Dual antiplatelet agents and Rivaroxaban for massive intracoronary thrombus in STEMI, Nasiruddin Jamal and Mustaafa Bapumia

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Not So Grand Rounds, Sayed Karar and Haritha Saikumar

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Does upgrade to tri-ventricular pacemaker improve long-term clinical response in non-responders to biventricular cardiac resynchronization therapy?, Sharon Hw Man, Jeilan Mohamed, Shoaib Siddiqui, and G. André Ng

Respiratory function amongst asymptomatic HIV positive and HIV negative clients at Aga Khan University Hospital, Nairobi, Noah Kipkemei Murbiy

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Gender differences in clinical characteristics and outcome of acute heart failure in sub-Saharan Africa: results of the THESUS-HF study, Okechukwu S. Ogah, Beth A. Davison, Karen Sliwa, Bongani M. Mayosi, Albertino Damasceno, Mahmoud U. Sani, Charles Mondo, Anastase Dzudie, Dike B. Ojji, Charles Kouam, Ahmed Suliman, Neshaad Schrueder, Gerald Yonga, Sergine Abdou Ba, Fikru Maru, Bekele Alemayehu, Christopher Edwards, and Gad Cotter

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Association between traumatic events and post-traumatic stress disorder: results from the ESEMeD-Spain study, B Olaya, J Alonso, Lukoye Atwoli, R C. Kessler, G Vilagut, and J M. Haro

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Symptoms of depression among patients attending a diabetes care clinic in rural western Kenya, Kristen Shirey, Simon M. Manyara, Lukoye Atwoli, Ryan Tomlin, Benson Gakinya, Stephanie Cheng, Jemima Kamano, Jeremiah Laktabai, and Sonak Pastakia

Comparison of cardiovascular risk profiles amongst newly diagnosed cancer patients and non-cancer patients at the Aga Khan University Hospital Nairobi, Majid Lingani-Ncube Sikosana

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Mortality Across Two ART Trials Enrolling at ≤200 vs ≤350 CD4 cells/uL in Kenya, Rachel A. Silverman, Michael Chung, James N. Kiarie, Nelly Yatich, Julia Njoroge, Catherine Kiptiness, Samah Sakr, Grace John-Stewart, and Lisa Frenkel

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Atrial fibrillation in sub-saharan Africa: epidemiology, unmet needs, and treatment options, Bruce Sheldon Stambler and Mzee Ngunga

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Characterization of in-hospital cardiac arrest in adult patients at a tertiary hospital in Kenya, Benjamin Wachira

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Uchunguzi (Journal Watch/Montre de journal) June 2015, Benjamin Wachira

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Uchunguzi (Journal WatchMontre de Journal) March 2015, Benjamin Wachira

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Uchunguzi (Journal Watch/Montre de journal) September 2015, Benjamin Wachira

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Building comprehensive and sustainable health informatics institutions in developing countries: Moi University experience, Martin C. Were, Abraham Siika, Paul O. Ayuo, Lukoye Atwoli, and Fabian Esamai

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Initial Impressions and Review of Literature Concerning Factors Affecting the Use of Palliative Care Assessment Tools in an African Setting, John Weru

Submissions from 2014

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Impact of somatic comorbidities on quality of life of patients living with epilepsy in Sagamu, Nigeria, Philip Adebayo, Rufus O. Akinyemi, Folashade Oluwole, Shamsideen A. Ogun, and Adesola Ogunniyi

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Gestational headaches: characteristics and influencing factors in SouthWestern Nigeria, Philip Adebayo, Aramide Mikhail Tijani, Olukayode Abayomi, and Adeseye Abiodun Akintunde

Incidence and risk factors for acute myocardial injury after non-cardiac surgery at the Aga Khan University hospital Nairobi, Salim Said Ahmed

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Impact of domestic care environment on trauma and posttraumatic stress disorder among orphans in western Kenya, Lukoye Atwoli, David Ayuku, Joseph Hogan, Julius Koech, Rachel Christine Vreeman, Samuel Ayaya, and Paula Braitstein

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The government of Kenya cash transfer for orphaned and vulnerable children: cross-sectional comparison of household and individual characteristics of those with and without, Lukoye Atwoli, Lonnie Embleton, Julius Koech, Paula Braitstein, and Allan Kamanda

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Association between parental psychopathology and suicidal behavior among adult offspring: results from the cross-sectional South African Stress and Health survey, Lukoye Atwoli, Matthew K. Nock, David R. Williams, and Dan J. Stein

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Rationale and design of the Pan-African sudden cardiac death survey: The Pan-African SCD study, Aimé Bonny, Marcus Ngantcha, Sylvie Ndongo Amougou, Adama Kane, Sonia Marrakchi, Emmy Okello, Georges Taty, Abdulrrazzak Gehani, Mamadou Diakite, Mohammed Talle, Pier Lambiase, Martin Houenassi, Ashley Chin, Harun Otieno, Gloria Temu, Isaac Koffi Owusu, Kamilu Karaye, Abdalla AM Awad, Bo Bo Gregers Winkel, and Silvia Priori

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Oligonucleotide ligation assay detects HIV drug resistance associated with virologic failure among antiretroviral-naive adults in Kenya, Michael Chung, Ingrid A. Beck, Sandra Dross, Kenneth Tapia, James N. Kiarie, Barbra A. Richardson, Julie Overbaugh, Samah R. Sakr, Grace C. John-Stewart, and Lisa M. Frenkel

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Leflunomide or methotrexate? Comparison of clinical efficacy and safety in low socio-economic rheumatoid arthritis patients, Muhammad Ishaq, Jibran Sualeh Muhammad, Kamran Hamid, and Ahmad Iqbal Mirza Ahmad Iqbal Mirza

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Clinical features, proximate causes, and consequences of active convulsive epilepsy in Africa, Symon M. Kariuki, William Matuja, Albert Akpalu, Angelina Kakooza-Mwesige, Martin Chabi, Ryan G. Wagner, Myles Connor, Eddie Chengo, Anthony K. Ngugi, Rachael Odhiambo, Christian Bottomley, Steven White, Josemir W. Sander, Brian G. R. Neville, and Charles R. J. C. Newton

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Effect of surgical subspecialty training on patent ductus arteriosus ligation outcomes, Dor Markush, Kelleigh E. Briden, Michael Chung, Katherine W. Herbst, Trudy J. Lerer, Stephen Neff, Amy C. Wu, and Brendan T. Campbell

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Interventions to promote adherence to antiretroviral therapy in Africa: a network meta-analysis, Edward J. Mills, Richard Lester, Kristian Thorlund, Maria Lorenzi, Katherine Muldoon, Steve Kanters, Sebastian Linnemayr, Robert Gross, Yvette Calderon, K Rivet Amico, Harsha Thirumurthy, Cynthia Pearson, Robert H. Remien, Lawrence Mbuagbaw, Lehana Thabane, Michael Chung, Ira B. Wilson, Albert Liu, Olalekan A. Uthman, Jane Simoni, David Bangsberg, Sanni Yaya, Till Bärnighausen, Nathan Ford, and Jean B. Nachega

Comparison of cardiometabolic risk profile between HIV patients on art and those who are art naïve, Erick Kimani Njenga

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Machado–Joseph disease in a Nigerian family: mutational origin and review of the literature, Shamsideen Abayomi Ogun, Sandra Martins, Philip Adebayo, Clara O. Dawodu, Jorge Sequeiros, and Michael F. Finkel

Prevalence and clinical characteristics of venous thromboembolism at the Aga Khan University hospital, Nairobi, Felix Mutuma Riunga

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DSM‐5 and ICD‐11 definitions of posttraumatic stress disorder: Investigating “narrow” and “broad” approaches, Dan J. Stein, Katie A. McLaughlin, Karestan C. Koenen, Lukoye Atwoli, Matthew J. Friedman, Eric D. Hill, Andreas Maercker, Maria Petukhova, Victoria Shahly, and Mark van Ommeren

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Emerging antiretroviral drug resistance in sub-Saharan Africa: novel affordable technologies are needed to provide resistance testing for individual and public health benefits, Gert U. van Zyl, Lisa M. Frenkel, Michael Chung, Wolfgang Preiser, John W. Mellors, and Jean B. Nachega

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Acute management of ST-elevation myocardial infarction in a tertiary hospital in Kenya: are we complying with practice guidelines?, Benjamin Wachira, Andrew Owuor, and Harun Otieno

Submissions from 2013

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HIV-1 progression links with viral genetic variability and subtype, and patient’s HLA type: analysis of a Nairobi-Kenyan cohort, Syed Hani Abidi, Aniqa Shahid, Laila S. Lakhani, Reena Shah, Nancy Okinda, Peter Ojwang, Farhat Abbas, Sarah Rowland-Jones, and Syed Ali

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Breaking bad news in clinical setting - health professionals' experience and perceived competence in southwestern Nigeria: A cross sectional study, Philip Adebayo, Olukayode Abayomi, Peter O. Johnson, Taofeeq Oloyede, and Abimbola A. Oyelekan

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Neuropsychiatric and Parkinsonian manifestations of dementia: A case report in a Nigerian woman, Philip Adebayo, Ajan A. Ajani, Olaleye A. Adenij, and Rufus O. Akinyemi

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Anthropometric differences among natives of Abuja living in urban and rural communities: correlations with other cardiovascular risk factors, Olufemi Sola Adediran, Philip Adebayo, and Adeseye Abiodun Akintunde

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Carotid atherosclerosis and right ventricular diastolic dysfunction in a sample of hypertensive Nigerian patients, Adeseye A. Akintunde, Philip Adebayo, Ademola A. Aremu, and Oladimeji G. Opadijo

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Trauma and posttraumatic stress disorder in South Africa: analysis from the South African Stress and Health Study, Lukoye Atwoli, Dan J. Stein, David R. Williams, Katie A. Mclaughlin, Maria Petukhova, Ronald C. Kessler, and Karestan C. Koenen

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Comparing Papanicolau smear, visual inspection with acetic acid and human papillomavirus cervical cancer screening methods among HIV-positive women by immune status and antiretroviral therapy, Michael Chung, K. P. McKenzie, H. D. Vuyst, B. A. Richardson, Farzana Rana, R. Pamnani, J. W. Njoroge, E. Nyongesa-Malava, S. R. Sakr, G. C. John-Stewart, and N. R. Mugo

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The journey of addiction: Barriers to and facilitators of drug use cessation among street children and youths in Western Kenya, Lonnie Embleton, Lukoye Atwoli, David Ayuku, and Paula Braitstein

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Harnessing the power of the grassroots to conduct public health research in sub-Saharan Africa: a case study from western Kenya in the adaptation of community-based participatory research (CBPR) approaches, Allan Kamanda, Lonnie Embleton, David Ayuku, Lukoye Atwoli, Peter Gisore, Samuel Ayaya, Rachel Vreeman, and Paula Braitstein

Effect of mobile phone short message service on adherence rates to antihypertensives at the Family Medicine Clinic, Barbara Karau

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The muranga teleophthalmology study: comparison of virtual (teleglaucoma) with in-person clinical assessment to diagnose glaucoma, Dan Kiage, Irfan N. Kherani, Stephen Gichuhi, Karim F. Damji, and Muindi Nyenze

Prevalence and factors associated with depression among patients with epilepsy in a Kenyan tertiary care hospital, Nduku Kiko

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Substance use among inmates at the Eldoret prison in Western Kenya, Daniel WC Kinyanjui and Lukoye Atwoli

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Improving diabetic retinopathy screening in Africa: Patient satisfaction with teleophthalmology versus ophthalmologist-based screening, K. Kurji, D. Kiage, C. J. Rudnisky, and K. F. Damji

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The prevalence of post-traumatic stress disorder among sexually abused children at kenyatta national hospital in Nairobi, Kenya, C. A. OMBOK, A. Obondo, and Lukoye Atwoli

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Clinical characteristics and outcomes of atrial fibrillation and flutter at the Aga Khan University Hospital, Nairobi, Jay Shavadia, Gerald Yonga, Sitna Mwanzi, Ashna Jinah, Abednego Moriasi, and Harun Otieno

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Readmission and death after an acute heart failure event: predictors and outcomes in sub-saharan africa: results from the thesus-hf registry, K. Sliwa, B. A. Davison, B. M. Mayosi, A. Damasceno, M. Sani, O. S. Ogah, C. Mondo, D. Ojji, A. Dzudie, C. K. Kouam, A. Suliman, N. Schrueder, Gerald Yonga, S. A. Ba, F. Maru, B. Alemayehu, C. Edwards, and G. Cotter

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Major incidents in Kenya: the case for emergency services development and training, Benjamin Wachira and Wayne Smith

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The prevalence of smoking and the knowledge of smoking hazards and smoking cessation strategies among hiv positive patients in johannesburg, south africa, Peter Waweru, R. Anderson, H. Steel, WDF. Venter, D. Murdoch, and C. Feldman

Submissions from 2012

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Short-term diagnostic stability among re-admitted psychiatric in-patients in Eldoret, Kenya, Lukoye Atwoli, D. Ndambuki, P. OWITI, G. Manguro, and N. Omulimi

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The causes, treatment, and outcome of acute heart failure in 1006 Africans From 9 countries, Albertino Damasceno, Bongani M. Mayosi, Mahmoud Sani, Okechukwu S. Ogah, Charles Mondo, Dike Ojji, Anastase Dzudie, Charles Kouam Kouam, Ahmed Suliman, Neshaad Schrueder, Gerald Yonga, Serigne Abdou Ba, Fikru Maru, Bekele Alemayehu, Christopher Edwards, Beth A. Davison, Gad Cotter, and Karen Sliwa

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The use of bevacizumab among women with metastatic breast cancer: a survey on clinical practice and the ongoing controversy., Shaheenah Dawood, Asim Jamal, Thomas A. Buchholz, Javier Cortes, Massimo Cristofanilli, Sudeep Gupta, and Ana M. Gonzalez‐Angulo

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Knowledge, attitudes, and substance use practices among street children in Western Kenya, Lonnie Embleton, David Ayuku, Lukoye Atwoli, Rachel Vreeman, and Paula Braitstein

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Risk of restless legs syndrome in low socioeconomic rheumatoidarthritis patients, Muhammad Ishaq, Jibran Sualeh Muhammad, and Kamran Hamid

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Adjuvant Hormonal Therapy in Postmenopausal Women with Breast Cancer: Physician's Choices, Asi Jamal, Shiyam Kumar, Sajjad Raza, Maria Mehboob, and Osama Ishtiaq

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Molecular Targeting Agents in Cancer Therapy: Science and Society, Asim Jamal

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Psychiatric morbidity among HIV-infected children and adolescents in a resource-poor Kenyan urban community, Judy W. Kamau, Wangari Kuria, Muthoni Mathai, Lukoye Atwoli, and Rachael Kangethe

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Preoperative medical consultation: maximizing its benefits, Raul A, Rivera; Nguyen T. Mai; Jorge I. Martinez-Osorio; Matthew F, McNeill; Sayed Karar; and Ishak A Mansi A. Mansi

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A prospective review of acute coronary syndromes in an urban hospital in sub-Saharan Africa, Jay Shavadia, Gerald Yonga, and Harun Otieno

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The influence of antiretroviral therapy on the QTc interval in an African cohort, J. Shavadia, Reena Shah, Gerald Yonga, R. Patel, J. Stebbing, and M. Nelson

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Community perspectives on research consent involving vulnerable children in Western Kenya, Rachel Vreeman, Eunice Kamaara, Allan Kamanda, David Ayuku, Winstone Nyandiko, Lukoye Atwoli, Samuel Ayaya, Peter Gisore, Michael Scanlon, and Paula Braitstein

Submissions from 2011

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Postpartum Depression, Lukoye Atwoli

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Prevalence of substance use among college students in Eldoret, western Kenya, Lukoye Atwoli, Prisca A. Mungla, Moses N. Ndung'u, Kiende C. Kinoti, and Evans M. Ogot

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Attention deficit hyperactivity disorder symptom self-report among medical students in Eldoret, Kenya, Lukoye Atwoli, P. Owiti, G. Manguro, and D. NDAMBUKI

Hepatitis B vaccination rate and determining factors amongst health care workers at Aga Khan University Hospital, Nairobi, Herman Ekea

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Comparison of Complete Versus Incomplete Stent Frame Expansion After Transcatheter Aortic Valve Implantation With Medtronic Coke Valve Bioprosthesis, Hasan Jilaihawi, Derek Chin, Tomasz J. Spyt, Jeilan Mohamed, Mariuca Vasa-Nicotera, Noor Mohamed, Johan Bence, Elaine Logtens, and Jan Kovac

The influence of depression on adherence to antiretroviral therapy among HIV infected patients at Aga Khan University Hospital (Nairobi), Evelyn W. Karanja-Mbugua

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Cytological diagnosis of typical carcinoid on bronchoscopic brush smears in an HIV-positive patient, Neeta Kumar, Shahin Sayed, and Swati Das

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159 Pilot Study exploring the regional repolarisation instability index in relation to myocardial heterogeneity and prediction of ventricular arrhythmia and death, William B. Nicolson, Christopher D. Steadman, P. Brown, Jeilan Mohamed, S. Yusuf, S Kundu, A. J. Sandilands, P. J. Stafford, F. S. Schlindwein, G. P. McCann, and G. Andre Ng

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Regional fractionation and dominant frequency in persistent atrial fibrillation: effects of left atrial ablation and evidence of spatial relationship, Jiun Tuan, Jeilan Mohamed, Suman Kundu, Will Nicolson, Irene Chung, Peter J. Stafford, and G. André Ng

An analysis of the clinical practice of emergency medicine in public emergency centres in Kenya, Benjamin W. Wachira

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Outbreak of beriberi among African union troops in Mogadishu, Somalia, John T. Watson, Hassan El Bushra, Emmaculate J. Lebo, Godfrey Bwire, James Kiyengo, Gideon Emukule, Victor Omballa, John Tole, Muvunyi Zuberi, Robert F. Breiman, and Mark A. Katz

Submissions from 2010

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Emergency mental health and psychosocial support for survivors of post-election violence in Eldoret, Kenya, Lukoye Atwoli

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Self-reported Attention Deficit and Hyperactivity Disorder symptoms among university students in Eldoret, Kenya, Lukoye Atwoli, P. Owiti, G. Manguro, and D. NDAMBUKI