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Submissions from 2015

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An unfinished agenda on adolescent health: Opportunities for interventions, Zohra S. Lassi, Rehana A. Salam, Jai K. Das, Kerri Wazny, and Zulfiqar A. Bhutta

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Impact of a community-based perinatal and newborn preventive care package on perinatal and neonatal mortality in a remote mountainous district in Northern Pakistan, Zahid Memon, Gul N Khan, Sajid Bashir Soofi, Imam Y Baig, and Zulfiqar Ahmed Bhutta

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Monovalent type-1 oral poliovirus vaccine given at short intervals in Pakistan: a randomised controlled, four-arm, open-label, non-inferiority trial, Fatima Mir, Farheen Quadri, Ondrej Mach, Imran Ahmed, Zaid Bhatti, Asia Khan, Najeeb Ur Rehman, Elias Durry, Maha Salama, and Steven M. Oberste

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Can routine screening and iron supplementation for iron deficiency anemia in nonsymptomatic pregnant women improve maternal and infant health outcomes?, Anoosh Moin and Zohra S. Lassi

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Sarcoidosis with Arteriovenous Malformation in a 15-Year-Old Girl - The Rarest of the Rare, Iman Qaiser, Kanwal Nayani, Shakeel Ahmed, Rehan Ali, and Mehnaz Atiq

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Challenges in measuring complications and death due to invasive Salmonella infections, Farah Naz Qamar, Asma Azmatullah, and Zulfiqar A. Bhutta

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The development and reliability of an observational tool for assessing mother-child interactions in field studies- experience from Pakistan, M A. Rasheed and A K. Yousafzai

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Pakistan and the Millennium Development Goals for Maternal and Child Health: progress and the way forward, Arjumand Rizvi, Zaid Bhatti, Jai K. Das, and Zulfiqar A. Bhutta

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Effect of clopidogrel on platelet CD markers in normal individuals and in patients with untreated type 2 diabetes mellitus, Muhammad Saboor, Moinuddin, and Samina Ilyas

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The changing landscape of malnutrition: why it matters, Rehana A. Salam and Zulfiqar A. Bhutta

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Effect of emollient therapy on clinical outcomes in preterm neonates in Pakistan: a randomised controlled trial, Rehana A. Salam, Gary L. Darmstadt, and Zulfiqar A. Bhutta

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Diagnosis and management of preeclampsia in community settings in low and middle-income countries, Rehana A. Salam, Jai K. Das, Anum Ali, Soumyadeep Bhaumik, and Zohra S. Lassi

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Current issues and priorities in childhood nutrition, growth, and infections, Rehana A. Salam, Jai K. Das, and Zulfiqar A. Bhutta

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Impact of Haemophilus influenzae type B (Hib) and viral influenza vaccinations in pregnancy for improving maternal, neonatal and infant health outcomes, Rehana A. Salam, Jai K. Das, Chesarahmia Dojo Soeandy, Zohra S. Lassi, and Zulfiqar A. Bhutta

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Use of N-acetylcysteine in children with fulminant hepatic failure caused by acute viral hepatitis, Ali Faisal Saleem, Qalab Abbas, and Anwarul Haque

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Isoniazid induced acute pancreatitis in a young girl, Ali Faisal Saleem Dr, Saba Arbab, and Farah Qamar Naz

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Immunogenicity of poliovirus vaccines in chronically malnourished infants: a randomized controlled trial in Pakistan, Ali Faisal Saleem, Ondrej Mach, Farheen Quadri, Asia Khan, Zaid Bhatti, Najeeb Ur Rehman, Sohail Zaidi, William C. Weldon, Steven M. Oberste, and Maha Salama

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Hospital preparedness in community measles outbreaks-challenges and recommendations for low-resource settings, Sadia Shakoor, Fatima Mir, Anita Zaidi, and Afia Zafar

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Mortality patterns among critically ill children in a Pediatric Intensive Care Unit of a developing country, Naveed-Ur-Rehman Siddiqui, Zohaib Ashraf, Humaira Jurair, and Anwarul Haque

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Predictors and outcome of tetanus in newborns in slum areas of Karachi city: A case control study, Arjumand Sohaila, Yasir Shafiq, Shazia Azim, Benazir Baloch, Ali Syed Muhammad Akhtar, Shiyam Sunder Tikmani, and Nick Brown

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Diagnostic accuracy of WHO verbal autopsy tool for ascertaining causes of neonatal deaths in the urban setting of Pakistan: a hospital-based prospective study, Sajid Bashir Soofi, Shabina Ariff, Ubaidullah Khan, Ali Turab, Gul Nawaz Khan, Atif Habib, Kamran Sadiq, Zamir Suhag, Zaid Bhatti, Imran Ahmed, Rajiv Bhal, and Zulfiqar Ahmed Bhutta

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Whole-exome sequencing in the clinic: Lessons from six consecutive cases from the clinician's perspective, Amber Volk, Erin Conboy, Beverly Wical, Marc Patterson, and Salman Kirmani

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Barriers and Facilitators of Compliance with Universal Precautions at First Level Health Facilities in Northern Rural Pakistan, Mohammad Tahir Yousafzai, Naveed Zafar Janjua, Amna Rehana Siddiqui, and Shafquat Rozi

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Abdominal Lymphonodular Cryptococcosis in an Immunocompetent Child, Mehjabeen Zaidi, Sonia Qureshi, Sadia Shakoor, Saira Fatima, and Fatima Mir

Submissions from 2014

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Burden of neurological illnesses in a pediatric intensive careunit of developing country, Qalab Abbas, Amber Shabbir, Naveedur Rehman Siddiqui, Raman Kumar, and Anwarul Haque

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Adrenal insufficiency in a child with MELAS syndrome, Bushra Afroze, Nida Amjad, Shahnaz Ibrahim, Khadija Nuzhat Humayun, and Yusnita Yakob

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The MAL-ED study: A multinational and multidisciplinary approach to understand the relationship between enteric pathogens, malnutrition, gut physiology, physical growth, cognitive development, and immune responses in infants and children up to 2 years of age in resource-poor environments, Imran Ahmed, Didar Alam, Syed Asad Ali, Zulfiqar Ahmed Bhutta, Shahida Qureshi, Sadia Shakoor, Sajid Bashir Soofi, Ali Turab, Aisha Khizar Yousafzai, and Anita K. M. Zaidi

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Clinical and biochemical characteristics of children with juvenile idiopathic arthritis, Shakeel Ahmed, Syed Rehan Ali, Sidra Ishaque, and Nabil Sami

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Vascular ehlers-danlos syndrome: a rare disorder presenting with focal convulsions, Shakeel Ahmed, Syed Rehan Ali, Naila Nadeem, and Muhammad Hamid

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Risk factors for complicated varicella infection in pediatric oncology patients at a tertiary health care facility in Pakistan, Muhammad Matloob Alam, Farah Naz Qamar, Zalan Wahid Khan, Vikram Kumar, Naureen Mushtaq, and Zehra Fadoo

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Neonatal sepsis following prolonged rupture of membranes in a tertiary care hospital in Karachi, Pakistan, Muhammad Matloob Alam, Ali Faisal Saleem, Abdul Sattar Shaikh, Owais Munir, and Maqbool Qadir

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Global practices of meningococcal vaccine use and impact on invasive disease, Syed Asad Ali, Rabab Batool, Nancy Messonnier, Carol Tevi-Benissan, David Durrheim, Juhani Eskola, Florence Fermon, Keith P. Klugman, Mary Ramsay, and Zulfiqar Ahmed Bhutta

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Impact of different dosing schedules on the immunogenicity of the human rotavirus vaccine in infants in Pakistan: a randomized trial, Syed Asad Ali, Abdul Momin Kazi, Margaret M. Cortese, Jessica A. Fleming, Umesh D. Parashar, Baoming Jiang, Monica Malone McNeal, Duncan Steele, Zulfiqar Bhutta, and Anita Zaidi

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Acute cerebellitis with hydrocephalus, Nida Amjad, Anwarul Haque, and Khalid Ahmed

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Absorbed zinc and exchangeable zinc pool size are greater in Pakistani infants receiving traditional complementary foods with zinc-fortified micronutrient powder, Shabina Ariff, Nancy F. Krebs, Sajid Soofi, Jamie Westcott, Zaid Bhatti, Farhana Tabassum, and Zulfiqar A. Bhutta

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Community based interventions for the prevention and control of tuberculosis, Ahmed Arshad, Rehana A. Salam, Zohra S. Lassi, Jai K. Das, Imama Naqvi, and Zulfiqar A. Bhutta

Gender differences in self esteem in young adolescents of Karachi, Shelina Bhamani, Sabeen Jamil, and Falak Zehra Mohsin

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Immunogenicity and safety of the Vi-CRM197 conjugate vaccine against typhoid fever in adults, children, and infants in south and southeast Asia: results from two randomised, observer-blind, age de-escalation, phase 2 trials, Zulfiqar A Bhutta, Maria Rosario Capeding, Ashish Bavdekar, Elisa Marchetti, Shabina Ariff, Sajid B Soofi, Alessandra Anemona, Atif Habib, Edison Alberto, Sanjay Juvekar, Rana M Qasim Khan, Rachid Marhaba, Noshad Ali, Nelia Malubay, Anand Kawade, Allan Saul, Laura B Martin, and Audino Podda

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Antibiotics to promote growth in children?, Zulfiqar Ahmed Bhutta

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Infectious disease: Polio eradication hinges on child health in Pakistan, Zulfiqar Ahmed Bhutta

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Assessment of environmental enteropathy in the MAL-ED cohort study: Theoretical and analytic framework, Zulfiqar Ahmed Bhutta, Imran Ahmed, Didar Alam, Syed Asad Ali, Shahida Qureshi, Sadia Shakoor, Sajid Bashir Soofi, Ali Turab, Aisha Khizar Yousafzai, and Anita K. M. Zaidi

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Should research fraud be a crime?, Zulfiqar Ahmed Bhutta and Julian Crane

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A role for science investments in advancing newborn health, Zulfiqar Ahmed Bhutta and Gary L. Darmstadt

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Can available interventions end preventable deaths in mothers, newborn babies, and stillbirths, and at what cost?, Zulfiqar Ahmed Bhutta, Jai K. Das, Rajiv Bahl, Joy E. Lawn, Rehana A. Salam, Vinod K. Paul, M Jeeva Sankar, Hannah Blencowe, Arjumand Rizvi, Victoria B. Chou, and Neff Walker

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Interventions to Address Maternal and Childhood Undernutrition: Current Evidence, Zulfiqar Ahmed Bhutta and Das J. K

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Tackling the existing burden of infectious diseases in the developing world: existing gaps and the way forward, Zulfiqar Ahmed Bhutta, Rehana A. Salam, Jai K. Das, and Zohra S. Lassi

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Approaches to improve Quality of Care (QoC) for women and newborns: conclusions, evidence gaps and research priorities, Zulfiqar Ahmed Bhutta, Rehana A. Salam, Zohra S. Lassi, Anne Austin, and Ana Langer

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Global burden, distribution, and interventions for infectious diseases of poverty, Zulfiqar Ahmed Bhutta; Johannes Sommerfeld; Zohra S. Lassi,; Rehana A. Salam; and Jai K Das

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Congenital mydriasis and prune belly syndrome in a child with an ACTA2 mutation, Michael C. Brodsky, Kadriye Erkan Turan, Cheryl L. Khanna, Alice Patton, and Salman Kirmani

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Erratum: Congenital mydriasis and prunebelly syndrome in a child with an ACTA2 mutation, Michael C. Brodsky, Kadriye Erkan Turan, Cheryl L. Khanna, Alice Patton, and Salman Kirmani

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Early recovery in post Varicella transverse myelitis, Prem Chand, Shahnaz brahim, Syed Sohail Zaidi, and Nida Amjad

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Community based interventions for the prevention and control of Non-Helmintic NTD, Jai K. Das, Rehana A. Salam, Ahmed Arshad, Hasina Maredia, and Zulfiqar A. Bhutta

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Global burden of childhood diarrhea and interventions, Jai K. Das, Rehana A. Salam, and Zulfiqar A. Bhutta

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Novel de novo SPOCK1 mutation in a proband with developmental delay, microcephaly and agenesis of corpus callosum, Radhika Dhamija, John M. Graham Jr, Nizar Smaoui, Erik Thorland, and Salman Kirmani

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A 7-year-old girl with hypertrophic cardiomyopathy and progressive scoliosis, Radhika Dhamija and Salman Kirmani

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Novel de novo heterozygous FGFR1 mutation in two siblings with Hartsfield syndrome: A case of gonadal mosaicism, Radhika Dhamija, Salman Kirmani, Xiangling Wang, Matthew J. Ferber, Eric D. Wieben, Konstantinos N. Lazaridis, and Dusica Babovic-Vuksanovic

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Bone strength and structural deficits in children and adolescents with a distal forearm fracture resulting from mild trauma, Joshua N. Farr, Shreyasee Amin, L. Joseph Melton III, Salman Kirmani, Louise K. McCready, Elizabeth J. Atkinson, Ralph Müller, and Sundeep Khosla

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Diminished bone strength is observed in adult women and men who sustained a mild trauma distal forearm fracture during childhood, Joshua N. Farr, Sundeep Khosla, Sara J. Achenbach, Elizabeth J. Atkinson, Salman Kirmani, Louise K. McCready, L Joseph Melton III, and Shreyasee Amin

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CT scan in children with acute bacterial meningitis: experience from emergency department of a tertiary-care hospital in Karachi, Pakistan, Jabeen Fayyaz, Arshalooz Rehman, Akhter Hamid, Munawar Khursheed, Nukhba Zia, Asher Feroze, and Uzma R. Khan

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Age related clinical manifestation of acute bacterial meningitis in children, Jabeen Fayyaz, Arshalooz Rehman, Akhter Hamid, Munawar Khursheed, Nukhbha Zia, and Asher Feroze

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Effects of estrogen on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in postmenopausal women, Koji Fujita, Matthew M. Roforth, Susan Demaray, Ulrike McGregor, Salman Kirmani, Louise K. McCready, James M. Peterson, Matthew T. Drake, David G. Monroe, and Sundeep Khosla

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Feasibility of pediatric plasma apheresis in intensive care settings, Anwarul Haque, Gul Sher, Mehar Hoda, and Bushra Moiz

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Short-term neonatal outcome in late preterm vs. term infants, Anila Haroon, Syed Rehan Ali, Shakeel Ahmed, and Humaira Maheen

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Disruption of MBD5 contributes to a spectrum of psychopathology and neurodevelopmental abnormalities, J C. Hodge, E Mitchell, V Pillalamarri, T L. Toler, F Bartel, H M. Kearney, Y S. Zou, W H. Tan, C Hanscom, and Salman Kirmani

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Evaluating associations between vaccine response and malnutrition, gut function, and enteric infections in the MAL-ED cohort study: Methods and challenges, Christel Hoest, Imran Ahmed, Didar Alam, Syed Asad Ali, Zulfiqar Ahmed Bhutta, Shahida Qureshi, Sadia Shakoor, Sajid Bashir Soofi, Ali Turab, Aisha Khizar Yousafzai, and Anita K. M. Zaidi

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The upsurge of SSPE--a reflection of national measles immunization status in Pakistan, Shahnaz Ibrahim, Nida Amjad, Ali Faisal Saleem Dr, Prem Chand, Arshad Rafique, and Khadija Nuzhat Humayun

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Culturable aerobic and facultative anaerobic intestinal bacterial flora of black cobra (Naja naja karachiensis) in southern Pakistan, Junaid Iqbal, Mehwish Sagheer, Nazneen Tabassum, Ruqaiyyah Siddiqui, and Naveed Ahmed Khan

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Sentinel hospital-based surveillance for assessment of burden of rotavirus gastroenteritis in children in Pakistan, Abdul Momin Kazi, Gohar Javed Warraich, Shahida Qureshi, Huma Qureshi, Muhammad Mubashir Ahmad Khan, and Anita Kaniz Mehdi Zaidi

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Monitoring polio supplementary immunization activities using an automated short text messaging system in Karachi, Pakistan, A M. Kazi, A Murtaza, S Khoja, A K. Zaidi, and S A. Ali

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Readmission to paediatric intensive care unit: frequency, causes and outcome, Muhammad Rehan Khan, Prem Kumar, Sumaira Iram, and Anwarul Haque

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Genetic Testing in Endocrinology, Salman Kirmani

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Antibiotic therapy versus no antibiotic therapy for children aged two to 59 months with WHO-defined non-severe pneumonia and wheeze, Zohra S. Lassi, Rohail Kumar, Jai K. Das, Rehana A. Salam, and Zulfiqar A. Bhutta

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The conceptual framework and assessment methodology for the systematic reviews of community-based interventions for the prevention and control of infectious diseases of poverty, Zohra S. Lassi, Rehana A. Salam, Jai K. Das, and Zulfiqar A. Bhutta

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Clinical manifestations and treatment outcomes in HIV-1-infected children receiving antiretroviral therapy in Karachi, Pakistan, Fatima Mir, Farah Naz Qamar, Naila Baig-Ansari, Azra Ghayas Abro, Syed Qamar Abbas, Mohammed Ahmed Kazi, Arjumand Rizvi, and Anita Kaniz Mehdi Zaidi

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Clinical Characteristics and Immediate-Outcome of Children Mechanically Ventilated in PICU of Pakistan, Beenish Mukhtar, Naveedur R. Siddiqui, and Anwarul Haque

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Fragile X syndrome due to a missense mutation, Leila K. Myrick, Mika Nakamoto-Kinoshita, Noralane M. Lindor, Salman Kirmani, Xiaodong Cheng, and Stephen T. Warren

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Theory-driven process evaluation of a complementary feeding trial in four countries, Jamie E. Newman, Ana Garces, Manolo Mazariegos, K Michael Hambidge, Albert Manasyan, Antoinette Tshefu, Adrien Lokangaka, Neelofar Sami, Waldemar A. Carlo, and Carl L. Bose

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Immune responses to Vi capsular polysaccharide typhoid vaccine in children 2 to 16 years old in Karachi, Pakistan, and Kolkata, India, R. Leon Ochiai, M. Imran Khan, Sajid B. Soofi, Dipika Sur, Suman Kanungo, Young Ae You, Atif Habib, Shah Muhammad Sahito, Byomkesh Manna, Camilo J. Acosta, Mohammad Ali, Sujit K. Bhattacharya, Zulfiqar A. Bhutta, and John D. Clemens

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A three-year review of antimicrobial resistance of Salmonella enterica serovars Typhi and Paratyphi A in Pakistan, Farah Naz Qamar, Asma Azmatullah, Abdul Momin Kazi, Erum Khan, and Anita Kaniz Mehdi Zaidi

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Subacute sclerosing panencephalitis: clinical and demographic characteristics, Arshad Rafique, Nida Amjad, Prem Chand, Syed Sohail Zahoor Zaidi, Muhammad Suleman Rana, Khalid Ahmed, and Shahnaz Ibrahim

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The MAL-ED cohort study: Methods and lessons learned when assessing early child development and caregiving mediators in infants and young children in 8 low- and middle-income countries, Muneera Rasheed, Aisha Khizar Yousafzai, (MAL-ED) Network Investigators, Imran Ahmed, Didar Alam, Syed Asad Ali, Zulfiqar Ahmed Bhutta, Shahida Qureshi, Sadia Shakoor, Sajid Bashir Soofi, Ali Turab, and Anita K. M. Zaidi

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Posterior mediastinal branchial cleft cyst: an unusual site, Abdul Rashid, Vaqas Ahmad, Saqib Qazi, Abdul Gaffar Billoo, Sajida Rashid, and Ali Faisal Saleem

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Modeling environmental influences on child growth in the MAL-ED cohort study: Opportunities and challenges, Stephanie A. Richard, Imran Ahmed, Didar Alam, Syed Asad Ali, Zulfiqar Ahmed Bhutta, Shahida Qureshi, Sadia Shakoor, Sajid Bashir Soofi, Ali Turab, Aisha Khizar Yousafzai, and Anita K. M. Zaidi

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Effects of age on bone mRNA levels of sclerostin and other genes relevant to bone metabolism in humans, Matthew M. Roforth, Koji Fujita, Ulrike I. McGregor, Salman Kirmani, Louise K. McCready, James M. Peterson, Matthew T. Drake, David G. Monroe, and Sundeep Khosla

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Impact of intrauterine growth restriction on long-term health, Rehana A. Salam, Jai K. Das, and Zulfiqar A. Bhutta

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Multiple micronutrient supplementation during pregnancy and lactation in low-to-middle-income developing country settings: impact on pregnancy outcomes, Rehana A. Salam, Jai K. Das, and Zulfiqar A. Bhutta

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Impact of community-based interventions for the prevention and control of malaria on intervention coverage and health outcomes for the prevention and control of malaria, Rehana A. Salam, Jai K. Das, Zohra S. Lassi, and Zulfiqar A. Bhutta

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Impact of community-based interventions on HIV knowledge, attitudes and transmission, Rehana A. Salam, Sarah Haroon, Hashim H. Ahmed, Jai K. Das, and Zulfiqar A. Bhutta

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Community-based interventions for the prevention and control of helmintic neglected tropical diseases, Rehana A. Salam, Hasina Maredia, Jai K. Das, Zohra S. Lassi, and Zulfiqar A. Bhutta

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Empyema thoracis in children: clinical presentation, management and complications, Ali Faisal Saleem, Abdul Sattar Shaikh, Reema Sajjad Khan, Fazal Khan, Ahmad Vaqas Faruque, and Muhammad Arif Mateen Khan

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Mutations in the neuronal vesicular SNARE VAMP2 affect synaptic membrane fusion and impair human neurodevelopment, Vincenzo Salpietro, Nancy T. Malintan, Isabel Llano-Rivas, Christine G. Spaeth, Stephanie Efthymiou, Pasquale Striano, Jana Vandrovcova, Salman Kirmani, Shahnaz Ibrahim, and Farida Jan

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Effect of L-type calcium channel blocker (amlodipine) on myocardial iron deposition in patients with thalassaemia with moderate-to-severe myocardial iron deposition: protocol for a randomised, controlled trial, Amarah Shakoor, Maaman Zahoor, Alina Sadaf, Najveen Alvi, Zehra Fadoo, Arjumand Rizvi, Farheen Quadri, Fateh Ali Tipoo, Mohammad Khurshid, Zaffar Sajjad, Steven Colan, and Babar S Hasan

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Pneumococcal serotypes and serogroups causing invasive disease in Pakistan, 2005-2013, Sadia Shakoor, Furqan Kabir, Asif R. Khowaja, Shahida M. Qureshi, Fyezah Jehan, Farah Qamar, Cynthia G. Whitney, and Anita K M Zaidi

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Multi-drug resistant gram negative infections and use of intravenous polymyxin B in critically ill children of developing country: Retrospective cohort study, Naveed-ur-Rehman Siddiqui, Farah Naz Qamar, Humaira Jurair, and Anwarul Haque

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Risk factors associated with birth asphyxia in rural district Matiari, Pakistan: A case control study, Farhana Tabassum, Arjumand Rizvi, Shabina Ariff, Sajid Bashir Soofi, and Zulfiqar Ahmed Bhutta

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Infant feeding practices, dietary adequacy, and micronutrient status measures in the MAL-ED study, Ali Turab, (MAL-ED) Network Investigators, Imran Ahmed, Didar Alam, Syed Asad Ali, Zulfiqar Ahmed Bhutta, Shahida Qureshi, Sadia Shakoor, Sajid Bashir Soofi, Ali Turab, Aisha Khizar Yousafzai, and Anita K. M. Zaidi

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Moving beyond prevalence studies: screening and interventions for children with disabilities in low-income and middle-income countries, Aisha K. Yousafzai, Paul Lynch, and Melissa Gladstone

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Capacity building in the health sector to improve care for child nutrition and development, Aisha K. Yousafzai, Muneera A. Rasheed, Bernadette Daelmans, Sheila Manji, Caroline Arnold, Raghu Lingam, Joshua Muskin, and Jane E. Lucas

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Recurrent Salmonellosis in a Child with Complete IL-12Rbeta1 Deficiency, Mohammad Faizan Zahid, Syed Asad Ali, Fyezah Jehan, Abdul Gaffar Billo, Jean-Laurent Casanova, Jacinta Bustamante, Stephanie Boisson-Dupuis, and Fatima Mir

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Frequency of cardiorenal syndrome type-I in hospitalized children with acute heart failure in a tertiary-care hospital, Mehjabeen Zaidi, Arshalooz Jamila Rehman, Anwarul Haque, Saleem Akhtar, and Prem Kumar Maheshwar