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Submissions from 2024

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Efficacy and safety of bedaquiline and delamanid in the treatment of drug-resistant tuberculosis in adults: A systematic review and meta-analysis, Syeda Hoorulain Ahmed, Hoorain Haider, Abdul Moeed, Aysal Mahmood, Syed Hasan Shuja, Javeria Hayat, Bushra Jamil, Nasir Shivani, and Razia Fatima

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Efficacy of dupilumab in eosinophilic esophagitis: A systematic review and meta-analysis of randomized controlled trials, Muhammad Aziz, Hossein Haghbin, Manesh Gangwani, Abeer Aziz, Dushyant Singh Dahiya, Hassam Ali, Wade Lee Smith, Hemant Goyal, and Faisal Kamal

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Analysis of impact of consumption of proton pump inhibitor on osseo integration of dental implants to the alveolar bone: A systematic critical appraisal, Abhishek Lal, Om Parkash, and Fahad Umer

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Mental health outcomes beyond the post-partum period among adolescent mothers: A systematic review and meta-analysis, Komal Abdul Rahim, Natasha J. Egglestone, Irakli G. Tsagareli, Wania Usmani, Salima Meherali, and Zohra S. Lassi

Submissions from 2023

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The spectrum of hereditary neuromuscular disorders in the Pakistani population, Fizza Akbar, Shafaq Muhammad Saleem, Ehtesham Khalid, Shahnaz Ibrahim, Bushra Afroze, Salman Kirmani, and Sara Khan

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Incidence of adverse cardiovascular events in patients with insomnia: A systematic review and meta-analysis of real-world data, Eman Ali, Asim Shaikh, Farah Yasmin, Ayesha Sheikh, Rabia Owais, Hamna Raheel, Hafeez Ul Hassan Virk, and Jihad A. Mustapha

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Comprehensive overview of human monkeypox: Epidemiology, clinical features, pathogenesis, diagnosis and prevention, Eman Ali, Ayesha Sheikh, Rabia Owais, Asim Shaikh, and Unaiza Naeem

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Role of iron in the reduction of anemia among women of reproductive age in low-middle income countries: Insights from systematic review and meta-analysis, Sumera Aziz Ali, Shama Razzaq, Savera Aziz, Ahreen Allana, Arzina Aziz Ali, Shahla Naeem, Nayab Khowaja, and Fazal Ur Rehman

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Splenic hematoma following acute pancreatitis, and the role of conservative management: A case report, Zulfeqar Ali, Muhammad Masood Karim, Maria Javeed, Qaisar Ali Khan, Christopher Farkou, David Zepeda, Parsa Abdi, Michelle Anthony, Matthew Farkouh, and Arooba Khan

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School Health Education Program in Pakistan (SHEPP): Findings from a feasibility trial in pre-adolescent school children from a lower middle-income country, Aysha Almas, Romaina Iqbal, Abdul Ghani, Zainab Samad, Sania Sabir, and Khawar Kazmi

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HepFREEPak: protocol for a multi-centre, prospective observational study examining efficacy and impact of current therapies for the treatment of hepatitis C in Pakistan and reporting resistance to antiviral drugs: study protocol, Ambreen Arif, Aliya Hasnain, Auj Chaudhry, Muhammad Asim, Polychronis Kemos, Noor Saba, Chris Metcalfe, Eleanor Barnes, Naheed Choudhry, and Saad Khalid Niaz

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Understanding prescribing practices and patient experiences with renin angiotensin system inhibitors use in chronic kidney disease: A qualitative study, Jennifer Arney, Sheena Wydermyer, L Parker Gregg, Michael A. Herrera, Peter A. Richardson, Michael E. Matheny, Julia M. Akeroyd, Glenn T. Gobbel, Adriana Hung, and Salim S. Virani

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Association between e-cigarette use and myocardial infarction: A systematic review and meta-analysis, Muhammad Talal Ashraf, Asim Shaikh, Muhammad Shakeel Khuzzaim Khan, Naseer Uddin, Muhammad Arham Bin Kashif, Syed Hassan Ahmed Rizvi, Hammad Khalid, Stafford Jude Sam, and Affan Sohail

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Best management of patients with malignant pericardial effusion: A comparative study between imaging-guided pericardiocentesis and surgical pericardial window, Abdul Baqi, Intisar Ahmed, and Pirbhat Shams

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Meplazumab in hospitalized adults with severe COVID-19 (DEFLECT): A multicenter, seamless phase 2/3, randomized, third-party double-blind clinical trial, Huijie Bian, Liang Chen, Zhao-Hui Zheng, Xiu-Xuan Sun, Jie-Jie Geng, Ruo Chen, Ke Wang, Xu Yang, Shi-Rui Chen, Si-Yu Chen, Nosheen Nasir, Iffat Khanum, Faisal Mahmood, and Saeed Hamid

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Urbanization and physical activity in the global prospective urban and rural epidemiology study, Kwadwo Boakye, Marit Bovbjerg, John Schuna Jr, Adam Branscum, Ravi Prasad Varma, Rosnah Ismail, Olga Barbarash, Juan Dominguez, Yuksel Altuntas, and Romaina Iqbal

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Is introduction of mental health education in dental school more important now than ever?, Nikita Bodani, Shweta Gohil, and Abhishek Lal

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Social Determinants of Health and Disparities in Hypertension and Cardiovascular Diseases, Abhishek Chaturvedi, Anqi Zhu, Naga Vaishnav Gadela, Dorairaj Prabhakaran, and Tazeen Jafar

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Challenges of managing hypertension in Pakistan - A review, Adil Elahi, Arzina Aziz Ali, Aamir Hameed Khan, Zainab Samad, Hunaina Shahab, Namra Aziz, and Aysha Almas

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Treatment of chronic hepatitis D with peginterferon lambda-the phase 2 LIMT-1 clinical trial, Ohad Etzion, Saeed Hamid, Yoav Lurie, Edward J. Gane, David Yardeni, Sarah Duehren, Nimrah Bader, Anat Nevo-Shor, Minaz Mawani, and Om Parkash

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Role of digital health tools in improving maternal and adolescent mental health services in Pakistan: A way forward, Armughan Tauheed Farooqui, Sehrish Karim, and Nurose Karim

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Evaluating glycemic control efficacy and safety of the oral small molecule glucagon-like peptide 1 receptor agonist Danuglipron in type 2 diabetes patients: A systemic review and meta-analysis, Hareer Fatima, Hussain Sohail Rangwala, Muhammad Saqlain Mustafa, Muhammad Ashir Shafique, Syed Raza Abbas, Azra Rizwan, Tagwa Kalool Fadlalla Ahmed, and Ainan Arshad

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Optimizing antibiotic duration for spontaneous bacterial peritonitis prophylaxis: Time to rethink, Manesh K. Gangwani, Abeer Aziz, Fnu Priyanka, Wade Lee Smith, Muhammad Aziz, and Mona Hassan

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Short versus long duration of dual antiplatelet therapy after second-generation drug-eluting stents implantation in patients with diabetes, Manesh Kumar Gangwani, Muhammad Aziz, Paul Chacko, Asif Mahmood, Muhammad Ali, Siraj Munir, Abeer Aziz, Shazib Sagheer, Shazib Sagheer, and Wade Lee-Smith

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Pakistan study of premature coronary atherosclerosis in young adults (pak-sehat): A prospective longitudinal study protocol investigating the prevalence, severity and determinants of atherosclerotic cardiovascular disease in the young adult pakistani population, Bashir Hanif, Sana Sheikh, Ghazal Peerwani, Miguel Cainzos Achirica, Wajiha Javed, Jaffer Bin Baqar, Zainab Samad, Faiza Bashir, Salim S. Virani, Khurram Nasir, and Saba Aijaz

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Frequency of extra pulmonary complications in critically ill COVID-19 patients and their association with inflammatory markers and hypoxia: Retrospective analysis at a tertiary care hospital in Karachi, Pakistan, Sadaf Hanif, Muhammad Sohaib, talha ejaz, and Asma Rayani

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Parental Knowledge, Attitude and Practices Toward Dental Sealants as Preventive Strategy for Dental Caries in Children: A Cross Sectional Study, Ayman Iftikhar; Aimen Imran; Mariam Wasif; Abhishek Lal; and Mkhitar Heratsi Yerevan State Medical University,USA

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Listeria monocytogenes outbreak – serendipity or emerging threat?, Memoona Irshad and Bushra Jamil

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Feasibility, enablers and challenges of using timeliness metrics for household contact tracing and TB preventive therapy in Pakistan, Bushra Jamil, Divya Nair, Pruthu Thekkur, Neelofar Laeeq, Anum Adil, Mohammed Khogali, Rony Zachariah, Selma Dar Berger, Srinath Satyanarayana, and Ajay M V Kumar

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Prolonged endoscopic retrograde cholangiography cannulation step-up protocol likely causing longer procedure time: A major confounding factor, Muhammad Masood Karim and Om Parkash

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Dysregulation of metalloproteins in ischemic heart disease patients with systolic dysfunction, Noman Khan, Junaid Ullah, Satwat Hashmi, Arslan Ali, Amna Jabbar Siddiqui, Shahid Ahmed Sami, Syedah Saira Bukhari, Hasanat Sharif, Jalal Uddin, and Hesham R. El-Seedi

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Data on non-communicable diseases: A missed opportunity in Pakistan, Sarim Dawar Khan, Tazeen Jafar, Kamran Siddiqi, Taimoor Ahmad, Adnan A. Khan, and Zainab Samad

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Factors associated with Diabetes Empowerment among patients with type 2 diabetes, at OPD setting, Karachi, Pakistan, Mohiba Ali Khowaja, Shafquat Rozi, Sobia Sawani, and Asma Ahmed

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Macrolides for better resolution of community-acquired pneumonia: A global meta-analysis of clinical outcomes with focus on microbial etiology, Miltiades Kyprianou, Konstantina Dakou, Aftab Aktar, Hichem Aouina, Naser Behbehani, Keertan Dheda, Georges Juvelekian, Adel Khattab, Bassam Mahboub, and Ali Bin Sarwar Zubairi

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Who tells the story of burns in low-and-middle income countries? – A bibliometric study, Shelley Lynn Wall, Lotta Velin, Aamir Abbas, Nikki Leigh Allorto, Mariana Graner, E. Moeller, Marcella Farrelle Dorothea Ryan-Coker, and Laura Pompermaier

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Trends in the burden and determinants of hypertensive heart disease in the Eastern Mediterranean region, 1990-2019: An analysis of the Global Burden of Disease Study 2019, Asieh Mansouri, Alireza Khosravi, Kamran Mehrabani-Zeinabad, Jacek A. Kopec, Karam I I Adawi, Michelle Lui, Hanan F. Abdul Rahim, Wagida Anwar, Ibtihal Fadhil, Kadhim Sulaiman, and Syedah Saira Bukhari

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Adolopment of adult diabetes mellitus management guidelines for a Pakistani context: Methodology and challenges, Russell Seth Martins, Qamar Masood, Omar Mahmud, Nashia Ali Rizvi, Aisha Sheikh, Najmul Islam, Anum Naushad Ali Khowaja, Nanik Ram, Saira Furqan, Mohsin Ali Mohsin, Salima Saleem Aamdani, Alina Pervez, Adil H. Haider, and Sarah Nadeem

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Diagnostic accuracy of different cut-off values of adenosine deaminase levels in tuberculous pleural effusion, Kiran Iqbal Masood, Shayan Shahid, Kauser Jabeen, Joveria Farooqi, Sabeika Raza Kerawala, and Muhammad Irfan

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Reply to: "Does currently recommended maternal antiviral prophylaxis against mother-to-child transmission of hepatitis B virus require enhancement?", Philippa C. Matthews, Ponsiano Ocama, Su Wang, Manal El Sayed, Anna Turkova, Deborah Ford, Judith Torimiro, Homie Razavi, Geoffrey Dusheiko, and Saeed Hamid

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Utility of neutrophil to lymphocyte ratio to predict acute respiratory distress syndrome in COVID-19: Short communication, Kulsoom Bano Mehdi, Shahzeeba Jehan, Madiha Akhter, Meher Angez, and Nosheen Nasir

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Direct oral anticoagulants for the treatment of cerebral venous thrombosis - a protocol of an international phase IV study, Anita van de Munckhof, Mayte Sánchez van Kammen, Katarzyna Krzywicka, Sanjith Aaron, Diana Aguiar de Sousa, Florina Antochi, Antonio Arauz, Miguel A. Barboza, Adriana B. Conforto, and Mohammad Wasay

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Depressive symptoms and risk of acute stroke: INTERSTROKE case-control study, Robert P. Murphy, Catriona Reddin, Annika Rosengren, Conor Judge, Graeme J. Hankey, John Ferguson, Alberto Alvarez-Iglesias, Shahram Oveisgharan, Mohammad Wasay, and Clodagh McDermott

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Prevalence of familial hypercholesterolemia in a country-wide laboratory network in Pakistan: 10-year data from 988, 306 patients, Ali Aahil Noorali, Salma Tajuddin, Sarim Dawar Khan, Mushyada Ali, Rumi Chunara, Aysha Habib, Afia Zafar, Syedah Saira Bokhari, Salim S. Virani, and Zainab Samad

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Diabetes among muslims during ramadan: A narrative review, Rohan Kumar Ochani, Asim Shaikh, Simran Batra, Gauri Pikale, and Salim Surani

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Cardiovascular disease risk stratification in the Pakistani population with and without metabolic syndrome: A single centre cross-sectional study, Amber Hanif Palla, Asad Saulat Fatimi, Salim S. Virani, and Syeda Sadia Fatima

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Leveraging collaborative learning for improved heart failure care: Insights from Argentina, Mohummad Hassan Raza Raja, Tariq Ahmad, and Zainab Samad

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Vasoplegia: A review, Iqbal Ratnani, Rohan Kumar Ochani, Asim Shaikh, and Hafsa Nazir Jatoi

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Bronchoscopic management of hemoptysis caused by airway erosion from vascular coils, Hussain Ahmed Raza, Mohummad Hassan Raza Raja, Jefferson H. Chambers, Chakravarthy B. Reddy, and Majid Shafiq

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Workplace violence against healthcare workers in Pakistan; call for action, if not now, then when? A systematic review, Syeda Tayyaba Rehan, Mishal Shan, Syed Hasan Shuja, Zayeema Khan, Hassan Ul Hussain, Rohan Kumar Ochani, Asim Shaikh, Iqbal Ratnani, Abdulqadir J. Nashwan, and Salim Surani

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Hyponatremia causing factors and its association with disease severity and length of stay in COVID-19 patients: A retrospective study from tertiary care hospital, Fazal Ur Rehman, Syeda Tayyaba Rehan, Bakhtawar Jama Rind, Komal Vallian, Muhammad Sohaib Asgha, and Farrukh Omair

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Clinical manifestations and outcome of patients with primary amoebic meningoencephalitis in pakistan. A single-center experience, Shakeel Ur Rehman, Salman Farooq, Muhammad Bilal Tariq, Nosheen Nasir, Mohammad Wasay, Sobia Masood, and Musa Karim

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Double-chambered left ventricle: Diagnosis by CMR and review of the literature, Sheema Saadia, Aiysha Nasir, and Fateh Ali Tipoo Sultan

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The burden of ischemic heart disease and the epidemiologic transition in the eastern mediterranean region: 1990-2019, Masoumeh Sadeghi, Marjan Jamalian, Kamran Mehrabani-Zeinabad, Karam Turk-Adawi, Jacek Kopec, Wael AlMahmeed, Hanan F. Abdul Rahim, Hasan Ali Farhan, Wagida Anwar, and Saira Bokhari

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Effect of cotton dust exposure on respiratory health outcomes among textile workers, Afreen Sadia, Yousaf Ali, Hasan Nawaz Tahir, Natasha Shaukat, Muhammad Irfan, and Asaad Ahmad Nafees

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Spontaneous large volume hemothorax managed with a small-bore chest tube, Moiz Salahuddin and Samia Ayub

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Outcomes of patients with elevated pulmonary artery systolic pressure on echocardiography due to chronic lung diseases, Moiz Salahuddin, Shayan Shahid, Masooma Aqeel, Ali Usman, Mehwish Aslam, and Saadia Sattar

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Impact of postoperative antibiotic prophylaxis on surgical site infections rates after mastectomy with drains but without immediate reconstruction: A multicenter, double-blinded, randomized control superiority trial, Abida K. Sattar, Taleaa Masroor, Russell Seth Martins, Nida Zahid, Hania Shahzad, Lubna Vohra, Sana Zeeshan, Irum Khan, Ayesha Afzal Qureshi, and Syed Faisal Mahmood

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Prevalence, Awareness, and Treatment of Elevated LDL Cholesterol in US Adults, 1999-2020, Ahmed Sayed

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Feto-maternal outcomes of pregnancies in women with SLE: Experience from a tertiary care center of Asia, Dur E. Shahwar, Tabeer Tanwir, Amir Raza, Mehmood Riaz, Ayesha Malik, and Shehla Ilyas

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The COVID-19 pandemic and coronary heart disease: The next surge, Asim Shaikh, Sarim Dawar Khan, Farhala Mari Baloch, Salim S. Virani, and Zainab Samad

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Etiology of acute infectious meningitis and meningoencephalitis in Karachi, Pakistan: Retrospective observational study from a tertiary care center, Sadia Shakoor, Tazeen Fatima, Fatima Mir, Asima Shahid, Najma Shaheen, Erum Khan, and Bushra Jamil

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Identifying the early predictors of non-response to steroids in patients with flare of autoimmune hepatitis causing acute-on-chronic liver failure, Sanchit Sharma, Samagra Agarwal, Anoop Saraya, Ashok Kumar Choudhury, Sanjiv Saigal, A. S. Soin, Akash Shukla, Manoj K. Sahu, Laurentius A. Lesmana, and Saeed Hamid

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COVID-19 and early puberty-An unintended consequence of COVID-19 lockdown?, Ayesha Sheikh, Rabia Owais, Eman Ali, and Asim Shaikh

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Contagion of coronavirus disease-the first family cluster of Pakistan: A case series, Aisha Fareed Siddiqui and Nosheen Nasir

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Genetic and antiretroviral drug resistance mutations analysis of reverse transcriptase and protease gene from Pakistani people living with HIV-1, Dilsha Siddiqui, Uzma Badar, Mahnoor Javaid, Nida Farooqui, Sharaf Ali Shah, Ayesha Iftikhar, Faisal Sultan, Fatima Mir, Syed Faisal Mahmood, and Syed Faisal Mahmood

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Portal vein thrombosis in patients with hepatocellular carcinoma and early cirrhosis-prevalence and risk factors, Muhammad Tayyab Ul-Hasan Siddiqui, Ghulam Fareed, Muhammad Rizwan Khan, Amna Riaz, and Saeed Hamid

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Cost-effectiveness of a multicomponent quality improvement care model for diabetes in South Asia: The CARRS randomized clinical trial, Kavita Singh, Dimple Kondal, V Usha Menon, Premlata K. Varthakavi, Vijay Viswanathan, Mala Dharmalingam, Ganapati Bantwal, Rakesh Kumar Sahay, Qamar Masood, and Rajesh Khadgawat

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Bilateral pneumothorax in a patient with angiosarcoma of the scalp: A case report, Maham Vaqar, Ayesha Sharif, Nousheen Iqbal, and Muhammad Irfan

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Neurological disorders and disability in Pakistan: A cross-sectional multicenter study, Mohammad Wasay, Safia Awan, Naila Shahbaz, Sara Khan, Khalid Sher, Abdul Malik, Shahid Mustafa, Alam Ibrahim Siddiqi, Saleem Barech, and Sajid Hameed

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Current practices and considerations for transcatheter mitral valve implantation based on risk stratification among patients with mitral valve regurgitation, Farah Yasmin, Hala Najeeb, Hasan Fareed Siddiqui, Muhammad Hamayl Zeeshan, Asad Mehdi, Muhammad Sohaib Asghar, Asim Shaikh, and Muhammad Aamir

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Global survey of stigma among physicians and patients with nonalcoholic fatty liver disease, Zobair M. Younossi, Saleh A. AlQahtani, Khalid Alswat, Yusuf Yilmaz, Caglayan Keklikkiran, Jesús Funuyet-Salas, Manuel Romero-Gómez, Jian-Gao Fan, Ming-Hua Zheng, and Saeed Hameed

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Clinical and patient-reported outcome profile of patients with hepatitis B viral infection from the Global Liver Registry™, Zobair M. Younossi, Ming-Lung Yu, Yusuf Yilmaz, Khalid Aida Alswat, Maria Buti, Marlen Ivon Castellanos Fernandez, Georgios Papatheodoridis, Saeed Hamid, Mohamed El-Kassas, and Wah Kheong Chan

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Medication adherence in patients with uncontrolled hypertension & hypertensive crisis presenting to a hospital setting in Karachi, Pakistan, Fatimah S. Yousuf, Muhammad Arbaz A. Khan, Raheela Bibi, Aiman Arif, Ainan Arshad, and Aysha Almas

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Basics of faculty-to-faculty mentoring: A process to identify support and challenges, Tabassum Zehra, Muhammed Tariq, Rehana Rehman, and Rukhsana W. Zuberi

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Hyftor: An Emerging Therapy For Facial Angiofibromas, Muhammad Hassan Zulfi, Zainab Abbas, and Elahi Sana Jilani

Submissions from 2022

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Efficacy and safety of direct oral anticoagulants with and without aspirin: A systematic review and meta-analysis, Talal Almas, Adeena Musheer, Arooba Ejaz, Fahd Niaz Shaikh, Anousheh Awais Paracha, Fizza Raza, Maryam Sarwar Khan, Fahad Masood, Faiza Siddiqui, and Muhammad Hasnain Mankani

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Healthcare simulation: A key to the future of medical education - A Review, Omair Ayaz and Faisal Wasim Ismail

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Spectrum of common pediatric neurological disorders: A cross-sectional study from three tertiary care centres across Pakistan, Prem Chand, Shahnaz Ibrahim, Khairunnisa Mukhtiar, Safia Awan, Durray Shahwar Abid Khan, Asna Sulaiman, Sajid Muhammad, Zahra Ali Padhani, Jai K. Das, and Mohammad Wasay

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Predictors of gastrointestinal bleeding in patients following left ventricular assist device implantation: A systematic review and meta-analysis, Manesh Kumar Gangwani, Muhammad Aziz, Ali Nawras, Fnu Priyanka, Zohaib Ahmed, Raja Samir Khan, Mohammad Aadil Qamar, Fawad Haroon, Abeer Aziz, and Wade Lee Smith

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South Asian ethnicity: What can we do to make this risk enhancer a risk equivalent?, Kartik Gupta, Mahmoud Al Rifai, Aliza Hussain, Abdul Mannan Khan Minhas, Jaideep Patel, Dinesh Kalra, Zainab Samad, and Salim S. Virani

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The emergence of COVID-19 associated mucormycosis: a review of cases from 18 countries, Martin Hoenigl, Danila Seidel, Agostinho Carvalho, Shivaprakash M. Rudramurthy, Amir Arastehfar, Jean-Pierre Gangneux, Nosheen Nasir, Alexandro Bonifaz, Javier Araiza, and Nikolai Klimko

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Post COVID-19 sequelae of the respiratory system. A single center experience reporting the compromise of the airway, alveolar and vascular components, Nousheen Iqbal, Iffat Khanum, Muhammad Ali Ibrahim Kazi, Syeda Urooj Riaz, Uzzam Ahmed Khawaja, Safia Awan, Muhammad Irfan, Ali Bin Sarwar Zubairi, and Javaid Khan

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Etiology, sensitivity and resistance pattern of urinary tract infection among children (0 To 16 Years), Manoj Kumar, Warda Khalid, Amin Ali, Syed Khurram Sajid, Yumna Muhammad Aslam, and Ayaz Ur Rehman

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Effectiveness of non-invasive respiratory support strategies in patients with COVID-19: A systematic review and meta analysis, Vinesh Kumar, Umair Arshad Malik, Reshman Kumari, Berkha Berkha, Vijay Kumar, Manoj Kumar, Simran Simran, Suman Suman, and Bushra Nasim

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COVID-19 infection among vaccinated and unvaccinated: Does it make any difference?, Fatima Samar, Amara Zafar, Haris Afzal, Taymmia Ejaz, Sara Shamim, Shayan Saleemi, and Amna Subhan Butt

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Clinical features, microbiology and lung function in post-TB bronchiectasis compared to other aetiologies, Shayan Shahid and Muhammad Irfan

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Time for reintroducing HPV vaccine in Pakistan for primary prevention of cervical cancer, Uzma Shamsi, Afshan Anwar, and Zainab Samad

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Acute variceal bleeding portends poor outcomes in patients with acute-on-chronic liver failure: A propensity score matched study from the APASL ACLF Research Consortium (AARC), Sanchit Sharma, Samagra Agarwal, Anoop Saraya, Ashok Choudhury, Mamun Al Mahtab, Mohd. Shahinul Alam, Sanjiv Saigal, Dong Joon Kim, C. E. Eapen, and Saeed Hamid

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Protocol for a cluster randomised controlled trial of secondary distribution of hepatitis C self-testing within the context of a house-to-house hepatitis C micro-elimination programme in Karachi, Pakistan, Sonjelle Shilton, Dania Ali, Alyia Hasnain, Adeel Abid, Jessica Markby, Muhammad S. Jamil, Niklas Luhmann, Pamela Nabeta, Stefano Ongarello, and Saeed Hamid

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Behavioural support and nicotine replacement therapy for smokeless tobacco cessation: Protocol for a pilot randomised-controlled multi-country trial, Faraz Siddiqui, Linda Bauld, Ray Croucher, Cath Jackson, Ian Kellar, Mona Kanaan, Subhash Pokhrel, Rumana Huque, Romaina Iqbal, and Javaid Ahmed Khan

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Acquired Hemophilia A: A possibly fatal complication of SARS-COV-2 infection, Hasan Fareed Siddiqui, Taymmia Ejaz, Aisha Fareed Siddiqui, and Fahd Niaz Shaikh

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Determinant of repeat revascularization within 5 years of percutaneous coronary lntervention at a tertiary care hospital, Karachi: A matched case-control study, Komal Valliani, Azmina Artani, Iqbal Azam, Javed Tai, and M. Masood Kadir

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Performance of Serum β2-Microglobulin- and β-Trace Protein-Based panel markers and 2021 Creatinine- and Cystatin-Based GFR estimating equations in Pakistan, Yeli Wang, Andrew S. Levey, Lesley A. Inker, Saleem Jessani, Rasool Bux, Zainab Samad, Sonia Yaqub, Amy B. Karger, John C. Allen, and Tazeen Jafar

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World Health Organization (WHO)'s Intersectoral Global Action Plan (IGAP); implications for Asian and African countries, Mohammad Wasay, Safa Younis, Augustina Charway-Felli, and Hamidon Basri

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Does individualized guided selection of antiplatelet therapy improve outcomes after percutaneous coronary intervention? A systematic review and meta-analysis, Naser Yamani, Samuel Unzek, Muhammad Hasnain Mankani, Talal Almas, Adeena Musheer, Humera Qamar, Shausha Farooq, Waqas Shahnawaz, Kaneez Fatima, and Vincent Figueredo

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Early transcatheter or surgical aortic valve replacement versus conservative management in asymptomatic patients with severe aortic stenosis: A systematic review and meta-analysis, Farah Yasmin, Asim Shaikh, Muhammad Sohaib Asghar, Hala Najeeb, Abdul Moeed, Eisha Waqar, Muskaan Doulat Ram, Avinash Nankani, Rohan Kumar Ochani, and Rumael Jawed

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The impact of the COVID-19 pandemic on patients with chronic liver disease: Results from the Global Liver Registry, Zobair M. Younossi, Yusuf Yilmaz, Mohamed El-Kassas, Ajay Duseja, Saeed Hamid, Gamal Esmat, Nahum Méndez-Sánchez, Wah Kheong Chan, Ashwani K. Singal, and Brian Lam

Submissions from 2021

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Lactoferrin reduces the risk of respiratory tract infections: A meta-analysis of randomized controlled trials, Akbar Shoukat Ali, Syed Shahzad Hasan, Chia Siang Kow, and Hamid A. Merchant

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Preliminary findings of a study on the practice of self-medication of antibiotics among the practicing nurses of a tertiary care hospital, Akbar Shoukat Ali, Rahim Jandani, Arwa A. Al-Qahtani, and Abdulkarem A S. Alenzi

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The mystery of COVID-19 reinfections: A global systematic review and meta-analysis, Rubaid Azhar Dhillon, Mohammad Aadil Qamar, Jaleed Ahmed Gilani, Omar Irfan, Usama Waqar, Mir Ibrahim Sajid, and Syed Faisal Mahmood