Submissions from 2022
Analysis of temporal changes in HIV-1 CRF01_AE gag genetic variability and CD8 T-cell epitope evolution, Wardah Rafaqat, Uroosa Tariq, Nida Farooqui, Maheen Zaidi, Aanish Raees, Maaz Zuberi, Amna Batool, and Syed Hani Abidi
HIV-1 genetic diversity a challenge for AIDS vaccine development: A retrospective bibliometric analysis, Abdur Rashid, Kang Li, Yi Feng, Tauseef Ahmad, Yimam Getaneh, Yueyang Yu, Xiaoyan Hu, Syed Hani Abidi, and Yiming Shao
Myrica salicifolia Hochst. ex A. Rich. suppress acetic acid-induced ulcerative colitis in rats by reducing TNF-alpha and interleukin-6, oxidative stress parameters and improving mucosal protection, N U. Rehman, M N. Ansari, Amber Hanif Palla, A Karim, F Imam, M Raish, A M. Hamad, and M Noman
Clinical case orientation with basic physiological concepts of endorcine reproductive physiology, Rehana Rehman and Syeda Sadia Fatima
Reflection of mentors and mentees at initiation of faculty mentorship program at Aga Khan university: A perspective, Rehana Rehman, Fauzia Khan, Naila Kayani, and Tazeen Saeed Ali
Teaching clinical skills using online modality through modified peyton’s framework: An experience from a medical university in Pakistan, sana saeed, Urooj Kashif, Samar Zaki, Khalid Samad, Muhammad Zuhair Yusuf, Mahanoor Raza, Shahjahan Jabbar, and Unab I. Khan
Galectin-3 mitigates cardiomyocytes injury through modulation of left ventricular cathepsins B, D, L and S at 24-hour post myocardial infarction, Suhail Al- Salam, Satwat Hashmi, and Govindan Jagadeesh
Gender-based violence in Pakistan and public health measures: A call to action, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz, and Zul Qarnain
Phylogenetic characterization of HIV-1 sub-subtype A1 in Karachi, Pakistan, Uroosa Tariq, Jamirah Nazziwa, Sviataslau Sasinovich, Sharaf Ali Shah, Sadaf Naeem, Syed Hani Abidi, and Joakim Esbjörnsson
Submissions from 2021
Non-compliance to social distancing during COVID-19 pandemic: A comparative cross-sectional study between the developed and developing countries, Faiqa Binte Aamir, Syeda Maria Ahmad Zaidi, Saadia Abbas, Syed Roohan Aamir, Syed Nauman Ahmad Zaidi, Karishma Kanhya Lal, and Syeda Sadia Fatima
Origin and evolution of HIV-1 subtype A6, Syed Hani Abidi, Lazzat Aibekova, Salima Davlidova, Aidana Amangeldiyeva, Brian Foley, and Syed Ali
Repurposing potential of posaconazole and grazoprevir as inhibitors of SARS-CoV-2 helicase, Syed Hani Abidi, Nahlah Makki Almansour, Daulet Amerzhanov, Khaled S. Allemailem, Wardah Rafaqat, Mahmoud A A. Ibrahim, Philip la Fleur, Martin Lukac, and Syed Ali
Phylogenetic and drug-resistance analysis of HIV-1 sequences from an extensive paediatric HIV-1 outbreak in Larkana, Pakistan, Syed Hani Abidi, George Makau Nduva, Dilsha Siddiqui, Wardah Rafaqat, Syed Faisal Mahmood, Amna Rehana Siddiqui, Apsara Ali, Aneeta Hotwani, Rashida Abbas Ferrand, and Fatima Mir
Therapeutic potential of curcumin in reversing the depression and associated pseudodementia via modulating stress hormone, hippocampal neurotransmitters, and BDNF levels in Rats, Asia Afzal, Zehra Batool, Sadia Sadir, Laraib Liaquat, Sidrah Shahzad, Saiqa Tabassum, Saara Ahmad, Noor Kamil, Tahira Perveen, and Saida Haider
Is hypothyroidism associated with outcomes in fracture patients? Data from a trauma registry, Tashfeen Ahmad, Zehra Abdul Muhammad, and Sarah Nadeem
Baseline MMP expression in periapical granuloma and its relationship with periapical wound healing after surgical endodontic treatment, Muhammad Adeel Ahmed, Muhammad Faraz Anwar, Khalid Ahmed, Marziya Aftab, Fizza Nazim, Muhammad Furqan Bari, Mohammed Mustafa, Fahim Vohra, Ali Alrahlah, Muhammad Nouman Mughal, and Syed Hani Abidi
Student research mentorship programme: A novel solution for promoting research in medical school, Inaara Akbar, Russell S. Martins, and Syeda Sadia Fatima
Multi-subunit SARS-CoV-2 vaccine design using evolutionarily conserved T- and B- cell epitopes, Burkitkan Akbay, Syed Hani Abidi, Mahmoud A A. Ibrahim, Zhussipbek Mukhatayev, and Syed Ali
Suggested role of silent information regulator 1 (SIRT1) gene in female infertility: A cross-sectional study in Pakistan, Faiza Alam, Rehana Rehman, Syeda Sadia Fatima, Mussarat Ashraf, and Taseer Ahmed Khan
Interplay between oxidative stress, SIRT1, reproductive and metabolic functions, Faiza Alam, Hareem Syed, Sofia Amjad, Mukhtiar Baig, Taseer Ahmed Khan, and Rehana Rehman
Association of novel stop-gained leukaemia inhibitory factor receptor gene (rs121912501) variant, leukaemia inhibitory factor and ovarian steroids with unexplained infertility among Pakistani women, Rabiya Ali, Mehir Un Nisa Iqbal, Rehana Rehman, and Taseer A. Khan
General public perception of social media, impact of covid-19 pandemic, and related misconceptions, Rabiya Ali, Shireen Jawed, Mukhtiar Baig, Ahmed Azam Malik, Fatima Syed, and Rehana Rehman
Genetic landscape of pancreatic adenocarcinoma patients: A pilot study from Pakistan, Saleema Mehboob Ali, Yumna Adnan, Zubair Ahmad, Hasnain Ahmed Farooqui, Tabish Chawla, and Syed Adnan Ali
Impact of a standardised parenteral nutrition protocol: A quality improvement experience from a NICU of a developing country, Gul Ambreen, Uswa Jiwani, Waqar Khowaja, Ali Shabbir Hussain, Kashif Hussain, Syed Shamim Raza, Arjumand Rizvi, Uzair Ansari, Khalil Ahmad, Simon Demas, and Shabina Ariff
Protamine 1/protamine 2 mRNA ratio in nonobstructive azoospermic patients, Sofia Amjad, Shamim Mushtaq, Rehana Rehman, Adnan Munir, Nida Zahid, and Pirzada Qasim Raza Siddique
Spermatozoa retrieval in azoospermia and expression profile of JMJD1A, TNP2, and PRM2 in a subset of the Karachi population, Sofia Amjad, Shamim Mushtaq, Rehana Rehman, Nida Zahid, Adnan Munir, and Pirzada Qasim Raza Siddiqui
Molecular and radiological characterization of glioblastoma multiforme using magnetic resonance imaging, Fazal M. Arain, Anjiya Shaikh, Muhammad Waqas, Muhammad Usman Tariq, Muhammad Faraz Raghib, Ghulam Haider, Muhammad Shahzad Shamim, Fatima Mubarak, Sheema H Hasan, Ather Enam, and Adnan Abdul Jabbar
Morphological changes in the experimental model of polycystic ovary syndrome and effects of vitamin D treatment, Arfa Azhar, Ghulam Haider, Zehra Naseem, Nida Farooqui, Mohammad U. Farooqui, and Rehana Rehman
Chronic long-COVID syndrome: A protracted COVID-19 illness with neurological dysfunctions, Abdul Mannan Baig
Counting the neurological cost of COVID-19, Abdul Mannan Baig
Pathways and pathogenesis of hearing deficits, tinnitus, and vertigo in COVID-19, Abdul Mannan Baig
Targeting neuroinvasion by SARS-CoV-2: Emerging trends in drug and antibody delivery to combat COVID-19, Abdul Mannan Baig
Docking prediction of levodopa in the receptor binding domain of spike protein of SARS-CoV-2, Abdul Mannan Baig, Areeba Khaleeq, Hira Syeda, and Noor Bibi
'Targeting the feast of a sleeping beast': Nutrient and mineral dependencies of encysted acanthamoeba castellanii, Abdul Mannan Baig, Naveed Ahmed Khan, Preet Katyara, Salima Lalani, Rozeena Baig, Mehdia Nadeem, Noor Akbar, Fizza Nazim, and Areeba Khaleeq
Online medical education and examinations during COVID-19: Perspectives of a teaching associate, Syed Mujtaba Baqir and Fatima Mustansir
Flipped laboratory sessions using video vignette and active learning: A hybrid approach for online teaching, Sabah Farhat, Rehana Rehman, and Syeda Sadia Fatima
Online assessment in undergraduate medical education: Challenges and solutions from a LMIC university, Syeda Sadia Fatima, Romana Idrees, Kauser Jabeen, Saniya Sabzwari, and Sadaf Khan
Association of chemerin gene promoter methylation in maternal blood and breast milk during gestational diabetes, Syeda Sadia Fatima, Rehana Rehman, Jibran Sualeh Muhammad, Russell S. Martins, Nuruddin Badruddin Mohammed, and Unab Khan
Spasmolytic effect of grewia asiatica fruit extract on isolated smooth muscles is mediated via multiple pathways, Muhammad Nabeel Ghayur, Saeed Ahmad, and Anwarul Hassan Gilani
On pandemics and pivots: A COVID-19 reflection on envisioning the future of medical education, Heeyoung Han, Amy Clithero-Eridon, Manuel João Costa, Caitriona A. Dennis, J Kevin Dorsey, Kulsoom Ghias, Alex Hopkins, Kauser Jabeen, Debra Klamen, and Sophia Matos
Pharmacist-directed vancomycin therapeutic drug monitoring in pediatric patients: A collaborative-practice model, Kashif Hussain, Rahila Ikram, Gul Ambreen, and Muhammad Sohail Salat
Meropenem-induced pancytopenia in a preterm neonate: A case report, Kashif Hussain, Muhammad Sohail Salat, Naureen Mohammad, Ambreen Mughal, Sidra Idrees, Javaid Iqbal, and Gul Ambreen
Blue biotechnology: Computational screening of sarcophyton cembranoid diterpenes for SARS-CoV-2 main protease inhibition, Mahmoud A A. Ibrahim, Alaa H M. Abdelrahman, Mohamed A M. Atia, Tarik A. Mohamed, Mahmoud F. Moustafa, Abdulrahim R. Hakami, Shaden A M. Khalifa, Fahad A. Alhumaydhi, Faris Alrumaihi, and Syed Hani Abidi
Biallelic variants in PCDHGC4 cause a novel neurodevelopmental syndrome with progressive microcephaly, seizures, and joint anomalies, Maria Iqbal, Reza Maroofian, Büşranur Çavdarlı, Florence Riccardi, Michael Field, Siddharth Banka, Dalal K. Bubshait, Yun Li, Jozef Hertecant, and Shahid Mahmood Baig
Gut integrity and duodenal enteropathogen burden in undernourished children with environmental enteric dysfunction, Zehra Jamil, Najeeha Talat Iqbal, Romana Idress, Zubair Ahmad, Kamran Sadiq, Junaid Iqbal, Sana Syed, Aneeta Hotwani, Furqan Kabir, Kumail Ahmed, Sheraz Ahmed, Fayyaz Umrani, Fatima Aziz, Adil Kalam, and Syed Asad Ali
A recurrent rare intronic variant in CAPN3 alters mRNA splicing and causes autosomal recessive limb-girdle muscular dystrophy-1 in three Pakistani pedigrees, Kamal Khan, Sarmad Mehmood, Chunyu Liu, Maimoona Siddiqui, Arsalan Ahmad, Belqees Yawar Faiz, Barry A. Chioza, Emma A. Baple, Muhammad I. Ullah, and Shahid Mahmood Baig
Quercetin exhibits potent antioxidant activity, restores motor and non-motor deficits induced by rotenone toxicity, Syeda Madiha, Zehra Batool, Saiqa Tabassum, Laraib Liaquat, Sadia Sadir, Sidrah Shahzad, Fizza Naqvi, Sadia Saleem, Sarwat Yousuf, and Saara Ahmad
Modifier genes in microcephaly: A report on WDR62, CEP63, RAD50 and PCNT variants exacerbating disease caused by biallelic mutations of ASPM and CENPJ, Ehtisham Ul Haq Makhdoom, Syeda Seema Waseem, Maria Iqbal, Uzma Abdullah, Ghulam Hussain, Maria Asif, Birgit Budde, Wolfgang Höhne, Ambrin Fatima, and Shahid Mahmood Baig
Molecular biology, Saara Muddasir
Systematic review of polyherbal combinations used in metabolic syndrome, Amber Hanif Palla, Faridah Amin, Bilqees Fatima, Arooj Shafiq, Najeeb Ur Rehman, Ikram Ul Haq, and Anwar-Ul-Hassan Gilani
Level I nodal positivity as a factor for involvement of the submandibular gland in oral cavity carcinoma: A case series report, Hamdan Ahmed Pasha, Rahim Dhanani, Shayan Khalid, Kulsoom Ghias, and Mumtaz Jamshed Khan
Endometriosis, infertility and MicroRNA's: A review, Mohummad Hasan Raza Raja, Nida Farooqui, Nadeem Zuberi, Mussarat Ashraf, Arfa Azhar, Rozeena Baig, Bisma Badar, and Rehana Rehman
A novel missense mutation in TNNI3K causes recessively inherited cardiac conduction disease in a consanguineous Pakistani family, Shafaq Ramzan, Stephanie Tennstedt Stephanie Tennstedt, Muhammad Tariq, Sheraz Khan, Hafiza Noor Ul Ayan, Aamir Ali, Matthias Munz, Holger Thiele, Asad Aslam Korejo, and Shahid Mahmood Baig
Editorial: Vitamin D deficiency and sufficiency in reproduction and bone metabolism, Rehana Rehman, Faiza Alam, Mukhtiar Baig, Aysha Habib Khan, and Naseer Ahmed
An innovation in flipped class room: A teaching model to facilitate synchronous and asynchronous learning during a pandemic, Rehana Rehman and Syeda Sadia Fatima
COVID-19 pandemic awareness, attitudes, and practices among the Pakistani general public, Rehana Rehman, Shireen Jawed, Rabiya Ali, Khola Noreen, Mukhtiar Baig, and Javaria Baig
Biomarkers for impending risk of osteoporosis in premenopausal women, Rehana Rehman, Ali Usman, Aisha Sheikh, and Rozeena Baig
Probabilistic measures of HIV-1 transmission in different HIV-1 key population groups of Larkana, Pakistan, Syed Rizwan-Ul-Hasa, Abiha Abdullah, Shakil Arshad Siddiqui, Shakil Ahmed, Sharaf Ali Shah, Fatima Mir, and Syed Hani Abidi
COVID-19 age-dependent immunology and clinical outcomes: Implications for vaccines, Azza Sarfraz, Saman Hasan Siddiqui, Junaid Iqbal, Syed Asad Ali, Zahra Hasan, Zouina Sarfraz, and Najeeha Talat Iqbal
Male infertility: Role of vitamin D and oxidative stress markers, Maheen Shahid, Sher Khan, Mussarat Ashraf, Hina Akram Mudassir, and Rehana Rehman
Relationship of BMI with Junk Food, sleep pattern, exam performance and awareness about its ill health effects in healthy teenagers, Saba Tariq, Sundus Tariq, Saffee Tariq, and Rehana Rehman
A recessive variant in TFAM causes mtDNA depletion associated with primary ovarian insufficiency, seizures, intellectual disability and hearing loss, Farid Ullah, Waqar Rauf, Kamal Khan, Sheraz Khan, Katrina M. Bell, Vanessa Cristina de Oliveira, Muhammad Tariq, Shabnam Bakhshalizadeh, Philippe Touraine, and Shahid Mahmood Baig
Pericardial fluid proteomic label-free quantification of differentially expressed proteins in ischemic heart disease patients with systolic dysfunction by nano-LC-ESI-MS/MS analysis, Junaid Ullah, Satwat Hashmi, Arslan Ali, Faisal Khan, Shahid Ahmed Sami, Nageeb Basir, Syedah Saira Bokhari, Hasanat Sharif, Hesham R. El-Seedi, and Syed Ghulam Musharraf
Identification of three novel pathogenic mutations in cystathionine beta-synthase gene of Pakistani intellectually disabled patients, Muhammad Wasim, Haq Nawaz Khan, Hina Ayesha, Mazhar Iqbal, Abdul Tawab, Muhammad Irfan, Warsha Kanhai, Susanna M I. Goorden, Lida Stroomer, and Gajja Salomons
P017 Small bowel transcriptomics define similarities and divergent pathways between Crohn, environmental enteric dysfunction (EED), and celiac diseases, implicating role for the microbiome in the pathogenesis, Y Haberman Ziv, Najeeha Talat Iqbal, T Braun, P J. Dexheimer, R Hadar, Najeeb Rehman, Sana Syed, C Moskaluk, S R. Moore, and Syed Asad Ali
Submissions from 2020
Depression screening, a prerequisite in patients undergoing investigative proto-oncogene mutation tests, Saara Ahmad, Asra Khan, and Bisma Badr
Functional and clinical outcomes of open versus closed radius and ulna shaft fractures in adults: A prospective cohort study, Tashfeen Ahmad, Zehra Abdul Muhammad, and Pervaiz Hashmi
Analysis of anti-microbial and anti-biofilm activity of hand washes and sanitizers against S. aureus and P. aeruginosa, Khalid Ahmed, Hamza Ahmed, Fasih Ali Ahmed, Alisha Akbar Ali, Jehangir Akbar, Junaid Rana, Uroosa Tariq, and Syed Hani Abidi
Fingolimod (FTY720) preserves high energy phosphates and improves cardiac function in heterotopic heart transplantation model, Naseer Ahmed, Javeria Farooq, Soban Sadiq, Sultan Ayoub Meo, Azam Jan, Faisal H. Cheema, Giuseppe Faggian, and Alessio Rungatscher
Protective role of peroxiredoxin-4 in heart failure, Naseer Ahmed, Masooma Naseem, and Javeria Farooq
Clinicopathologic features predictive of distant metastasis in patients diagnosed with invasive breast cancer, Basim Ali, Fatima Mubarik, Nida Zahid, and Abida K. Sattar
Galectin-3: A cardiomyocyte antiapoptotic mediator at 24-hour post myocardial infarction, Suhail Al-Salam, Satwat Hashmi, Govindan S. Jagadeesh, and Saeed Tariq
Neonatal fluid and electrolytes profile effect on amphotericin B associated nephrotoxicity in neonatal tertiary care unit of Karachi-Pakistan, Gul Ambreen, Arshalooz Rahman, Kashif Hussain, Mehreen Sohail, Saba Javed, Syed Shamim, Umer Ali, Khalil Ahmad, and Arjumand Rizvi
Efficacy of colistin in multidrug-resistant neonatal sepsis: Experience from a tertiary care center in Karachi, Pakistan, Gul Ambreen, Muhammad Sohail Salat, Kashif Hussain, Syed Shamim Raza, Umer Ali, Syed Iqbal Azam, Junaid Iqbal, and Zafar Fatmi
Association of long-term consumption of repeatedly heated mix vegetable oils in different doses and hepatic toxicity through fat accumulation, Gul Ambreen, Afshan Siddiq, and Kashif Hussain
Repeatedly heated mix vegetable oils-induced atherosclerosis and effects of murraya koenigii, Gul Ambreen, Afshan Siddiq, Kashif Hussain, Abdul Saboor Hussain, and Zara Naz
Synonymous polymorphism rs201256011 in dopamine receptor type 2 gene is associated with schizophrenia and PANSS score in Pakistani population: A first report, Qurat-Ul-Ain Amir, Farina Hanif, Washdev Washdev, Fareena Bilwani, and Shabana Usman Simjee
Application of an integrated cheminformatics-molecular docking approach for discovery for physicochemically similar analogs of fluoroquinolones as putative HCV inhibitors, Faraz Anwar, Ramsha Khalid, Alina Hasanain, Sadaf Naeem, Shamshad Zarina, Syed Hani Abidi, and Syed Ali
Polycystic ovary syndrome, subfertility and vitamin D deficiency, Arfa Azhar, Fatima Abid, and Rehana Rehman
Can neurotropic free-living amoeba serve as a model to study SARS-CoV-2 pathogenesis?, Abdul Mannan Baig
Chronic COVID syndrome: Need for an appropriate medical terminology for Long-COVID and COVID long-haulers, Abdul Mannan Baig
Computing the effects of SARS-CoV-2 on respiration regulatory mechanisms in COVID-19, Abdul Mannan Baig
Covert pathways to the cranial cavity: Could these be potential routes of SARS-CoV-2 to the brain?, Abdul Mannan Baig
Neurological manifestations in COVID-19 caused by SARS-CoV-2, Abdul Mannan Baig
Updates on what ACS reported: Emerging evidences of COVID-19 with nervous system involvement, Abdul Mannan Baig
Ocular COVID-19: Eyes as a reservoir to conceal and spread SARS-CoV-2, Abdul Mannan Baig, Saara Ahmad, Areeba Khaleeq, Hamna Rafique, Shafiqa Rajput, Meher Angez, Ayesha Nasir Hameed, Talha Nawaz, and Preet Katyara
First reports of effects of insulin, human-like insulin receptors and adapter proteins in Acanthamoeba castellanii, Abdul Mannan Baig and Areeba Khaleeq
Evidence of the COVID-19 virus targeting the CNS: Tissue distribution, host-virus interaction, and proposed neurotropic mechanisms, Abdul Mannan Baig, Areeba Khaleeq, Usman Ali, and Hira Syeda
Elucidation of cellular targets and exploitation of the receptor-binding domain of SARS-CoV-2 for vaccine and monoclonal antibody synthesis, Abdul Mannan Baig, Areeba Khaleeq, and Syeda Hira
Docking prediction of amantadine in the receptor binding domain of spike protein of SARS-CoV-2, Abdul Mannan Baig, Areeba Khaleeq, and Hira Syeda
Deleterious outcomes in long-hauler COVID-19: The effects of SARS-CoV-2 on the CNS in chronic COVID syndrome, Abdul Mannan Mannan Baig
Future oncotargets: Targeting overexpressed conserved protein targets in androgen independent prostate cancer cell lines, Abdul Mannan Baig, Zohaib Rana, Mohammad Mohsin Mannan, Areeba Khaleeq, Fizza Nazim, Preet Katyara, and Farhat Abbas
Heralding healthcare professionals: Recognition of neurological deficits in COVID-19, Abdul Mannan Baig and Erin C. Sanders
Potential neuroinvasive pathways of SARS-CoV-2: Deciphering the spectrum of neurological deficit seen in coronavirus disease 2019 (COVID-19), Abdul Mannan Baig and Erin C. Sanders
Survival on the heart transplant waiting list, Syed Shahyan Bakhtiyar, Elizabeth L. Godfrey, Shayan Ahmed, Harveen Lamba, Jeffrey Morgan, Gabriel Loor, Andrew Civitello, Faisal H. Cheema, Whitson B. Etheridge, John Goss, and Abbas Rana
Is dengue the new rising global health problem? The outbreak of 2019 in Pakistan, Mariam Baloch, Abdul Mannan Baig, and Rohan K. Ochani
Comparison of intraarticular distal humerus fracture outcomes treated with or without olecranon osteotomy - A case series, Naveed Baloch, Tashfeen Ahmad, and Zehra Abdul Muhammad
What does it mean for a case to be ‘local’? The importance of local relevance and resonance for bioethics education in the Asia-pacific region, Sara M. Bergstresser, Kulsoom Ghias, Stuart Lane, Wee-Ming Lau, Isabel S S. Hwang, Olivia M Y. Ngan, Robert L. Klitzman, and Ho Keung Ng
Alcohol consumption and obesity: The hidden scare with COVID-19 severity, Bushra Bilal, Faizan Saleem, and Syeda Sadia Fatima
Physician-scientist or basic scientist? Exploring the nature of clinicians' research engagement, Anna T. Cianciolo, Jordon Mitzelfelt, Allen Ghareeb, Mohammad Faizan Zahid, Rozmeen Akbar, and Kulsoom Ghias