Surgical outcomes and challenges in primary palatoplasty among adults: A retrospective cohort study of 395 patients
Document Type
Article
Department
Medical College Pakistan; Surgery
Abstract
Objective: To evaluate surgical outcomes and challenges associated with primary palatoplasty in adults.
Design: Retrospective cohort study
Setting: Lahore, Pakistan, from 2015 to 2024.
Patients/Participants: A total of 395 adult patients (≥18 years) with unrepaired overt cleft palate ± cleft lip undergoing primary palatoplasty (mean age = 21.6 years, 55.6% male, 44.4% female).
Interventions: Primary palatoplasty was performed using von Langenbeck, Bardach 2-flap, or midline incision-only techniques. Modifications for wide clefts and adjunctive pharyngeal flaps were used when indicated.
Main Outcome Measures: Postoperative fistula formation and speech outcomes
Results: Bilateral incomplete cleft palate (Veau II) was the most common phenotype (35.9%) encountered. Postoperative fistula formation occurred in 16.9% of patients, most commonly at the hard-soft palate junction. Increasing age was independently associated with fistula formation (adjusted odds ratio 1.05; 95% confidence interval (CI) 1.001-1.09; P = 0.04). Composite speech scores improved significantly from 14.6 ± 0.75 to 12.3 ± 1.41 (95% CI 2.15-2.45; P < 0.001), representing modest speech improvement.
Conclusion: Primary palatoplasty in adults remains technically challenging but can provide modest improvements in speech outcomes and functional communication.
Publication (Name of Journal)
The Cleft Palate Craniofacial Journal
DOI
10.1177/10556656261489252
Recommended Citation
Daiem, M.,
Fayyaz, G. Q.,
Irfan, S.,
Bashir, M. M.,
Bajwa, H.,
Turk, M.,
Chong, D.,
Alonso, N.,
Steinberg, J. P.,
Talat, N.,
Shamim, R.,
Miles, M. G.,
Vyas, R.,
Nolte, J.,
Breugem, C.
(2026). Surgical outcomes and challenges in primary palatoplasty among adults: A retrospective cohort study of 395 patients. The Cleft Palate Craniofacial Journal.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_surg_surg/993
Comments
Volume, issue, and pagination are not provided by the author/publisher.