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Submissions from 2021

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Repurposing potential of posaconazole and grazoprevir as inhibitors of SARS-CoV-2 helicase, Syed Hani Abidi, Nahlah Makki Almansour, Daulet Amerzhanov, Khaled S. Allemailem, Wardah Rafaqat, Mahmoud A A. Ibrahim, Philip la Fleur, Martin Lukac, and Syed Ali

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Suggested role of silent information regulator 1 (SIRT1) gene in female infertility: A cross-sectional study in Pakistan, Faiza Alam, Rehana Rehman, Syeda Sadia Fatima, Mussarat Ashraf, and Taseer Ahmed Khan

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Association of novel stop-gained leukaemia inhibitory factor receptor gene (rs121912501) variant, leukaemia inhibitory factor and ovarian steroids with unexplained infertility among Pakistani women, Rabiya Ali, Mehir Un Nisa Iqbal, Rehana Rehman, and Taseer A. Khan

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Protamine 1/protamine 2 mRNA ratio in nonobstructive azoospermic patients, Sofia Amjad, Shamim Mushtaq, Rehana Rehman, Adnan Munir, Nida Zahid, and Pirzada Qasim Raza Siddique

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Molecular and radiological characterization of glioblastoma multiforme using magnetic resonance imaging, Fazal M. Arain, Anjiya Shaikh, Muhammad Waqas, Muhammad Usman Tariq, Muhammad Faraz Raghib, Ghulam Haider, Muhammad Shahzad Shamim, Fatima Mubarak, Sheema H Hasan, Syed Ather Enam, and Adnan Abdul Jabbar

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Morphological changes in the experimental model of polycystic ovary syndrome and effects of vitamin D treatment, Arfa Azhar, Ghulam Haider, Zehra Naseem, Nida Farooqui, Mohammad U. Farooqui, and Rehana Rehman

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Docking prediction of levodopa in the receptor binding domain of spike protein of SARS-CoV-2, Abdul Mannan Baig, Areeba Khaleeq, Hira Syeda, and Noor Bibi

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'Targeting the feast of a sleeping beast': Nutrient and mineral dependencies of encysted acanthamoeba castellanii, Abdul Mannan Baig, Naveed Ahmed Khan, Preet Katyara, Salima Lalani, Rozeena Baig, Mehdia Nadeem, Noor Akbar, Fizza Nazim, and Areeba Khaleeq

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Online medical education and examinations during COVID-19: Perspectives of a teaching associate, Syed Mujtaba Baqir and Fatima Mustansir

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Association of chemerin gene promoter methylation in maternal blood and breast milk during gestational diabetes, Syeda Sadia Fatima, Rehana Rehman, Jibran Sualeh Muhammad, Russell S. Martins, Nuruddin Badruddin Mohammed, and Unab Khan

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Meropenem-induced pancytopenia in a preterm neonate: A case report, Kashif Hussain, Muhammad Sohail Salat, Naureen Mohammad, Ambreen Mughal, Sidra Idrees, Javaid Iqbal, and Gul Ambreen

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Endometriosis, infertility and MicroRNA's: A review, Mohummad Hasan Raza Raja, Nida Farooqui, Nadeem Zuberi, Mussarat Ashraf, Arfa Azhar, Rozeena Baig, Bisma Badar, and Rehana Rehman

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An innovation in flipped class room: A teaching model to facilitate synchronous and asynchronous learning during a pandemic, Rehana Rehman and Syeda Sadia Fatima

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Relationship of BMI with Junk Food, sleep pattern, exam performance and awareness about its ill health effects in healthy teenagers, Saba Tariq, Sundus Tariq, Saffee Tariq, and Rehana Rehman

Submissions from 2020

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Depression screening, a prerequisite in patients undergoing investigative proto-oncogene mutation tests, Saara Ahmad, Asra Khan, and Bisma Badr

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Functional and clinical outcomes of open versus closed radius and ulna shaft fractures in adults: A prospective cohort study, Tashfeen Ahmad, Zehra Abdul Muhammad, and Pervaiz Hashmi

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Analysis of anti-microbial and anti-biofilm activity of hand washes and sanitizers against S. aureus and P. aeruginosa, Khalid Ahmed, Hamza Ahmed, Fasih Ali Ahmed, Alisha Akbar Ali, Jehangir Akbar, Junaid Rana, Uroosa Tariq, and Syed Hani Abidi

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Fingolimod (FTY720) preserves high energy phosphates and improves cardiac function in heterotopic heart transplantation model, Naseer Ahmed, Javeria Farooq, Soban Sadiq, Sultan Ayoub Meo, Azam Jan, Faisal H. Cheema, Giuseppe Faggian, and Alessio Rungatscher

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Protective role of peroxiredoxin-4 in heart failure, Naseer Ahmed, Masooma Naseem, and Javeria Farooq

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Clinicopathologic features predictive of distant metastasis in patients diagnosed with invasive breast cancer, Basim Ali, Fatima Mubarik, Nida Zahid, and Abida K. Sattar

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Galectin-3: A cardiomyocyte antiapoptotic mediator at 24-hour post myocardial infarction, Suhail Al-Salam, Satwat Hashmi, Govindan S. Jagadeesh, and Saeed Tariq

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Neonatal fluid and electrolytes profile effect on amphotericin B associated nephrotoxicity in neonatal tertiary care unit of Karachi-Pakistan, Gul Ambreen, Arshalooz Rahman, Kashif Hussain, Mehreen Sohail, Saba Javed, Syed Shamim, Umer Ali, Khalil Ahmad, and Arjumand Rizvi

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Efficacy of colistin in multidrug-resistant neonatal sepsis: Experience from a tertiary care center in Karachi, Pakistan, Gul Ambreen, Muhammad Sohail Salat, Kashif Hussain, Syed Shamim Raza, Umer Ali, Syed Iqbal Azam, Junaid Iqbal, and Zafar Fatmi

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Association of long-term consumption of repeatedly heated mix vegetable oils in different doses and hepatic toxicity through fat accumulation, Gul Ambreen, Afshan Siddiq, and Kashif Hussain

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Repeatedly heated mix vegetable oils-induced atherosclerosis and effects of murraya koenigii, Gul Ambreen, Afshan Siddiq, Kashif Hussain, Abdul Saboor Hussain, and Zara Naz

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Synonymous polymorphism rs201256011 in dopamine receptor type 2 gene is associated with schizophrenia and PANSS score in Pakistani population: A first report, Qurat-Ul-Ain Amir, Farina Hanif, Washdev Washdev, Fareena Bilwani, and Shabana Usman Simjee

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Application of an integrated cheminformatics-molecular docking approach for discovery for physicochemically similar analogs of fluoroquinolones as putative HCV inhibitors, Faraz Anwar, Ramsha Khalid, Alina Hasanain, Sadaf Naeem, Shamshad Zarina, Syed Hani Abidi, and Syed Ali

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Polycystic ovary syndrome, subfertility and vitamin D deficiency, Arfa Azhar, Fatima Abid, and Rehana Rehman

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Can neurotropic free-living amoeba serve as a model to study SARS-CoV-2 pathogenesis?, Abdul Mannan Baig

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Chronic COVID syndrome: Need for an appropriate medical terminology for Long-COVID and COVID long-haulers, Abdul Mannan Baig

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Computing the effects of SARS-CoV-2 on respiration regulatory mechanisms in COVID-19, Abdul Mannan Baig

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Covert pathways to the cranial cavity: Could these be potential routes of SARS-CoV-2 to the brain?, Abdul Mannan Baig

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Neurological manifestations in COVID-19 caused by SARS-CoV-2, Abdul Mannan Baig

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Updates on what ACS reported: Emerging evidences of COVID-19 with nervous system involvement, Abdul Mannan Baig

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Ocular COVID-19: Eyes as a reservoir to conceal and spread SARS-CoV-2, Abdul Mannan Baig, Saara Ahmad, Areeba Khaleeq, Hamna Rafique, Shafiqa Rajput, Meher Angez, Ayesha Nasir Hameed, Talha Nawaz, and Preet Katyara

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Evidence of the COVID-19 virus targeting the CNS: Tissue distribution, host-virus interaction, and proposed neurotropic mechanisms, Abdul Mannan Baig, Areeba Khaleeq, Usman Ali, and Hira Syeda

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Elucidation of cellular targets and exploitation of the receptor-binding domain of SARS-CoV-2 for vaccine and monoclonal antibody synthesis, Abdul Mannan Baig, Areeba Khaleeq, and Syeda Hira

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Docking prediction of amantadine in the receptor binding domain of spike protein of SARS-CoV-2, Abdul Mannan Baig, Areeba Khaleeq, and Hira Syeda

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Deleterious outcomes in long-hauler COVID-19: The effects of SARS-CoV-2 on the CNS in chronic COVID syndrome, Abdul Mannan Mannan Baig

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Future oncotargets: Targeting overexpressed conserved protein targets in androgen independent prostate cancer cell lines, Abdul Mannan Baig, Zohaib Rana, Mohammad Mohsin Mannan, Areeba Khaleeq, Fizza Nazim, Preet Katyara, and Farhat Abbas

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Heralding healthcare professionals: Recognition of neurological deficits in COVID-19, Abdul Mannan Baig and Erin C. Sanders

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Potential neuroinvasive pathways of SARS-CoV-2: Deciphering the spectrum of neurological deficit seen in coronavirus disease 2019 (COVID-19), Abdul Mannan Baig and Erin C. Sanders

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Survival on the heart transplant waiting list, Syed Shahyan Bakhtiyar, Elizabeth L. Godfrey, Shayan Ahmed, Harveen Lamba, Jeffrey Morgan, Gabriel Loor, Andrew Civitello, Faisal H. Cheema, Whitson B. Etheridge, John Goss, and Abbas Rana

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Is dengue the new rising global health problem? The outbreak of 2019 in Pakistan, Mariam Baloch, Abdul Mannan Baig, and Rohan K. Ochani

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Comparison of intraarticular distal humerus fracture outcomes treated with or without olecranon osteotomy - A case series, Naveed Baloch, Tashfeen Ahmad, and Zehra Abdul Muhammad

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What does it mean for a case to be ‘local’? The importance of local relevance and resonance for bioethics education in the Asia-pacific region, Sara M. Bergstresser, Kulsoom Ghias, Stuart Lane, Wee-Ming Lau, Isabel S S. Hwang, Olivia M Y. Ngan, Robert L. Klitzman, and Ho Keung Ng

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Alcohol consumption and obesity: The hidden scare with COVID-19 severity, Bushra Bilal, Faizan Saleem, and Syeda Sadia Fatima

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Physician-scientist or basic scientist? Exploring the nature of clinicians' research engagement, Anna T. Cianciolo, Jordon Mitzelfelt, Allen Ghareeb, Mohammad Faizan Zahid, Rozmeen Akbar, and Kulsoom Ghias

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Revisiting respiratory syncytial virus's interaction with host immunity, towards novel therapeutics, C Efstathiou, Syed Hani Abidi, J Harker, and N J. Stevenson

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Role of some MiRNA affecting polycystic ovarian syndrome and SIRT1 levels, Nida Farooqui, Quratulain Maha, and Rehana Rehman

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Paediatric porphyria and human hemin: A treatment challenge in a lower middle income country, Syeda Anum Fatima, Humaira Jurair, Qalab Abbas, and Arshalooz Rahman

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Impact of humanities and social sciences curriculum in an undergraduate medical education programme, Kulsoom Ghias, Kausar S. Khan, Rukhsana Ali, Shireen Azfar, and Rashida Ahmed

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Naringenin protects AlCl3/D-galactose induced neurotoxicity in rat model of AD via attenuation of acetylcholinesterase levels and inhibition of oxidative stress, Saida Haider, Laraib Liaquat, Saara Muddasir, Zehra Batool, Rafat Ali Siddiqui, Saiqa Tabassum, Sidrah Shahzad, Sahar Rafiq, and Narjis Naz

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Supplementation of taurine insulates against oxidative stress, confers neuroprotection and attenuates memory impairment in noise stress exposed male wistar rats, Saida Haider, Irfan Sajid, Zehra Batool, Syeda Madiha, Sadia Sadir, Noor Kamil, Laraib Liaquat, Saara Ahmad, Saiqa Tabassum, and Saima Khaliq

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A novel variant in dopamine receptor type 2 gene is associated with schizophrenia, Farina Hanif, Qurat-Ul-Ain Amir, Washdev Washdev, Fareena Bilwani, Shabana Usman Simjee, and Zeba Haque

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An antibiotic stewardship program in a surgical ICU of a resource-limited country: Financial impact with improved clinical outcomes, Kashif Hussain, Muhammad Faisal Khan, Gul Ambreen, Syed Shamim Raza, Seema Irfan, Kiren Habib, and Hasnain Zafar

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Neurodevelopment outcome of neonates treated with intraventricular colistin for ventriculitis caused by multiple drug-resistant pathogens-A case series, Kashif Hussain, Muhammad Sohail Salat, Gul Ambreen, and Javaid Iqbal

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Intravenous vs intravenous plus aerosolized colistin for treatment of ventilator-associated pneumonia - A matched case-control study in neonates, Kashif Hussain, Muhammad Sohail Salat, Gul Ambreen, Ambreen Mughal, Sidra Idrees, Mehreen Sohail, and Javaid Iqbal

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Manuscript writing and publication workshop: An invoking pilot study on enhancing cognitive research capabilities in health sciences institutes of Pakistan, Mehwish Hussain, Rehana Rehman, and Mukhtiar Baig

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Neurological manifestations of COVID-19, Dureshahwar Kanwar, Abdul Mannan Baig, and Mohammad Wasay

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An in silico approach to analyze HCV genotype-specific binding-site variation and its effect on drug-protein interaction, Ramsha Khalid, Muhammad Faraz Anwar, Muhammad Aanish Raees, Sadaf Naeem, Syed Hani Abidi, and Syed Ali

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Understanding of metals dysregulation in patients with systolic and diastolic dysfunction in ischemic heart disease, Noman Khan, Satwat Hashmi, Amna Jabbar Siddiqui, Sabiha Farooq, Shahid Ahmed Sami, Nageeb Basir, Syeda Saira Bokhari, Hasanat Sharif, Sanaullah Junejo, Hesham R. El-Seedi, and Syed Ghulam Musharraf

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Technology-based learning tools in medical lab sessions, Sher Khan, Asra Khan, and Saara Ahmad

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HIV infection predominantly affecting children in Sindh, Pakistan, 2019: A cross-sectional study of an outbreak, Fatima Mir, Syed Faisal Mahmood, amna siddiqui, Shehla Baqi, Syed Hani Abidi, Abdul Momin Kazi, Aspara Ali, Amerta Ladhani, Farah Qamar, Sajid Bashir Soofi, Sikander Ali Memon, Jamila Soomro, Saqib Ali Shaikh, Victoria Simms, Palwasha Khan, and Rashida Abbas Ferrand

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Effects of feed additives on chicken growth and their residues in meat instigating deleterious consequences on the liver health of consumers - A prospective human study, Saara Muddasir, Iftikhar Ahmed, Saida Haider, Zehra Batool, Laraib Liaquat, Fatima Ahmed, Asra Khan, Tahira Perveen, Mirza Jawad ul Hasnain, Saima Khaliq, and Saad Bilal Ahmed

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Relation of copeptin with diabetic and renal function markers among patients with diabetes mellitus progressing towards diabetic nephropathy, Tooba Noor, Farina Hanif, Zareen Kiran, Rehana Rehman, Muhammad Tassaduq Khan, Zeba Haque, and Kelash Nankani

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Knowledge, attitudes, and practices against the growing threat of COVID-19 among medical students of Pakistan, Khola Noreen, Zil-E Rubab, Muhammad Umar, Rehana Rehman, Mukhtiar Baig, and Fizzah Baig

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Outbreak of coronavirus disease 2019 (COVID 19) in Pakistan: Psychological impact and coping strategies of health care professionals, Khola Noreen, Muhammad Umar, Syed Arshad Sabir, and Rehana Rehman

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Multiple mechanisms of flaxseed: Effectiveness in inflammatory bowel disease, Amber Hanif Palla, Anwar Gilani, Samra Bashir, and Najeeb Ur Rehman

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Association of polymorphism c.-124G>A and c.-16 C>T in the promoter region of human INHA gene with altered sperm parameters; a pilot study, Wardah Rafaqat, Muhammad Rohan Kayani, Tasneem Fatima, Saeeda Shaharyar, Shagufta Khan, Mussarat Ashraf, Usman Afzal, and Rehana Rehman

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Association of circulatory kisspeptin levels and hormonal interplay with male infertility: A cross-sectional study in Karachi, Pakistan, Rehana Rehman, Kaleem Ahmed, Nida Zahid, Faiza Alam, and Syeda Sadia Fatima

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Oxidative stress and male infertility: A cross sectional study, Rehana Rehman, Sofia Amjad, Hemaila Tariq, Nida Zahid, Masnoon Akhter, and Mussarat Ashraf

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Role of oxidative stress and altered thyroid hormones in unexplained infertility, Rehana Rehman, Hiba Ismail Rajpar, Mussarat Ashraf, Najeeha Talat Iqbal, Salima Lalani, and Faiza Alam

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Impact of wellness indicators on intellectual dimensions of medical teachers of Karachi: Findings from cross sectional study, Rehana Rehman, Sadiqa Syed, Mehwish Hussain, Tayyab Raza Fraz, and Saif Ullah Shaikh

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Impact of serum and follicular fluid kisspeptin and estradiol on oocyte maturity and endometrial thickness among unexplained infertile females during ICSI, Rehana Rehman, Amara Zafar, Arzina Aziz Ali, Mukhtiar Baig, and Faiza Alam

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Altered sperm parameters and subclinical hypothyroidism; a cross sectional study in Karachi, Pakistan, Rehana Rehman, Amara Zafar, Syeda Sadia Fatima, Alina Mohib, and Aisha Sheikh

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Follicular sensitivity index: A tool to predict successful conception after intra-cytoplasmic sperm injection, Rehana Rehman, Amara Zafar, Nida Zahid, and Nuruddin Badruddin Mohammed

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Rethinking toxicity testing: Influence of aging on the outcome of long-term toxicity testing and possible remediation, Shakil Ahmed Saghir, Rais Ahmad Ansari, and Michael A. Dorato

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HBV S antigen evolution in the backdrop of HDV infection affects epitope processing and presentation, Mehwish Sajjad, Syed Ali, Samina Baig, Shaheen Sharafat, Bilal Ahmed Khan, Saeed Khan, Muhammad Nouman Mughal, and Syed Hani Abidi

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Epidemiology of shigella infections and diarrhea in the first two years of life using culture-independent diagnostics in 8 low-resource settings, Fariha Shaheen, Furqan Kabir, Arjumand Rizvi, Fatima Aziz, Adil Kalam, Shahida Qureshi, Sadia Shakoor, Ali Turab, Sajid Bashir Soofi, Zulfiqar Ahmed Bhutta, and Najeeha Talat Iqbal

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Does lipocalin-2 affect metabolic syndrome in hepatic infections?, Waqas Shahnawaz, Nawal Suhail, Muhammad Ahsan Iqbal Siddiqui, Saira Yasmeen, and Syeda Sadia Fatima

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Inhibition of soluble epoxide hydrolase offers protection against fructose-induced diabetes and related metabolic complications in rats, S Ali Shah, ‪Malik Hassan Mehmood, M Khan, I A. Bukhari, B I. Alorainey, and F Vohra

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Spirulina platensis (Blue-green algae): A miracle from sea combats the oxidative stress and improves behavioral deficits in an animal model of schizophrenia, Sidrah Shahzad, Zehra Batool, Saiqa Tabassum, Saara Ahmad, Noor Kamil, Saima Khaliq, Amber Nawaz, and Saida Haider

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Peer-assisted learning (PAL): An innovation aimed at engaged learning for undergraduate medical students, Hasan Salman Siddiqi, Rehana Rehman, Farzeen Fatma Syed, Russell S. Martins, Muhammad Talal Ibrahim, and Faiza Alam

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Free l-glutamate-induced modulation in oxidative and neurochemical profile contributes to enhancement in locomotor and memory performance in male rats, Saiqa Tabassum, Saara Ahmad, Syeda Madiha, Sidrah Shahzad, Zehra Batool, Sadia Sadir, and Saida Haider

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The emergence of an unassigned complex recombinant form in a Pakistani HIV-infected individual, Uroosa Tariq, Ayesha Iftikhar, Dilsha Zahid, Faisal Sultan, Syed Faisal Mahmood, Sadaf Naeem Sadaf Naeem, Syed Ali, and Syed Hani Abidi

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Higher DNA methylation of ABO gene promoter is associated with acute myocardial infarction in a hospital-based population in Karachi, Farzana Abubakar Yousuf, Khawar Kazmi, Junaid Iqbal, Nikhat Ahmed, and Mohammad Perwaiz Iqbal

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Genetic aberrations involved in relapse of pediatric acute myeloid leukemia: A literature review, Naveera Zafar, Kulsoom Ghias, and Zehra Fadoo

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MicroRNA-16, programmed cell death protein-4 (PDCD-4) and polycystic ovarian syndrome, Naseem Zehra, Arfa Azhar, and Rehana Rehman

Submissions from 2019

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The antibiofilm activity of acetylsalicylic acid, mefenamic acid, acetaminophen against biofilms formed by P. aeruginosa and S. epidermidis, Syed Hani Abidi, Khalid Ahmed, and Shahana Urooj Kazmi

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Implications of genetic variation of common drug metabolizing enzymes and ABC transporters among the Pakistani population, Nasir Ali Afsar, Henrike Bruckmueller, Anneke Nina Werk, Muhammad Kashif Nisa, H R. Ahmad, and Ingolf Cascorbi

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Gene lifestyle interactions with relation to obesity, cardiometabolic, and cardiovascular traits among South Asians, Shafqat Ahmad, Syeda Sadia Fatima, Gull Rukh, and Caren E. Smith

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Cardioprotective mechanism of FTY720 in ischemia reperfusion injury, Naseer Ahmed

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Fingolimod plays role in attenuation of myocardial injury related to experimental model of cardiac arrest and extracorporeal life support resuscitation, Naseer Ahmed, Abid Laghari, Bashar AlBkhoor, Sobia Tabassum, Sultan Ayoub Meo, Nazeer Muhammad, Daniele Linardi, Abeer A. Al-Masri, Guido Fumagalli, Giovanni Battista Luciani, Giuseppe Faggian, and Alessio Rungatscher

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Cardioprotective effects of sphingosine-1-phosphate receptor immunomodulator fty720 in a clinically relevant model of cardioplegic arrest and cardiopulmonary bypass, Naseer Ahmed, Adeela Mehmood, Daniele Linardi, Soban Sadiq Sadiq, Maddalena Tessari, Sultan Ayoub Meo, Rehana Rehman, Waseem M. Hajjar, Nazeer Muhammad, Mohammad Iqbal, Anwar Gilani, Giuseppe Faggian, and Alessio Rungatscher

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Coronary sinus ablation is a key player substrate in recurrence of persistent atrial fibrillation, Naseer Ahmed, Shahida Perveen, A. Mehmood., G. F. Rani, and G. Molon

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Role of Ajwa date (Phoenix Dactyl L) derived polyphenols in male infertility, Naseer Ahmed, Rehana Rehman, and Anwar Gilani

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Association of oxidative stress with female infertility - a case control study, Faiza Alam, Taseer Ahmed Khan, Sofia Amjad, and Rehana Rehman

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Suppressor of cytokine signaling-3 in pregnant females with or without hypertension, Huma Shoukat Ali, Mubeen Ali, Sabah Farhat, and Syeda Sadia Fatima

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Education Of females And impact On fertility, Rabiya Ali and Rehana Rehman