Enhanced dietary monitoring using fecal genomics for childhood malnutrition interventions

Document Type

Artefact

Department

Community Health Sciences; Biological and Biomedical Sciences

Abstract

Ready-to-use therapeutic and supplementary foods (RUTF/RUSF) are a primary treatment for childhood malnutrition in Community Management of Acute Malnutrition (CMAM) programs. However, measuring intervention compliance is labor intensive and unreliable. We applied FoodSeq, a fecal genomic dietary assessment biomarker, in malnourished infants (3-15 months) from Matiari, Pakistan. FoodSeq identified a significant increase in the abundance of DNA from chickpea, a primary RUSF ingredient, during RUSF administration and captured region-specific complementary feeding practices, including age-inappropriate feeding practices such as wide-spread tea consumption. Our findings highlight the potential of dietary genomics as an empirical and scalable tool for compliance monitoring and dietary analysis in community-based malnutrition programs.

Publication (Name of Journal)

Food & Function

DOI

10.1039/d5fo02791h

Share

COinS