Factors associated with fresh stillbirths of e 28 weeks of gestation at tertiary care hospital of Pakistan: A case-control study

Date of Award


Document Type


Degree Name

Master of Science in Epidemiology & Biostatistics (MSc Epidemiology & Biostats)


Community Health Sciences


Every year, 1.3 million fresh stillbirths occur globally. A large number of these fresh stillbirths occur in Sub-Saharan Africa and South Asia. Pakistan has the highest burden of stillbirth and the rate of fresh stillbirth is 14/1000 births which are preventable with appropriate obstetric care. The objective of the study was to determine factors associated with fresh stillbirth among women delivering at? 28 weeks of gestation. Methods: A case-control study was conducted between May to Aug 2019. Cases were the fresh stillborn of > 28 weeks of gestation and control were the livebirths of > 28 weeks of gestation. We enrolled 90 cases and 312 controls in this study. In addition to face to face interviews, the maternal information was also extracted from the patient files. Logistic regression analysis was performed to determine the factors associated with fresh stillbirth. Results: The following factors were found to be associated with an increased risk for fresh stillbirth:no maternal education (AOR 2.46, 95% CI=1.17 — 5.21), not received antenatal care during index pregnancy (AOR 3.11, 95% C1=1.39 — 6.96), recreational substance use (AOR 3.38, 95% CI=1.46 — 7.81), medical illness in index pregnancy (AOR 5.73, 95% CI=2.70 - 12.19), mother who had been referral from other facility (AOR 2.26, 95% CI=-1.06 — 4.82), preterm birth (AOR 2.04, 95% CI-=1.01 — 4.09) and low birth weight (AOR 10.84, 95% CI=5.09 — 23.07). Conclusion: Illitracy, no antenatal care, medical illness in index pregnancy, habit of using recreational substances, preterm and low birth weight were associated with fresh stillbirth.

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