Helicobacter pylori colonization in infants in a peri-urban community in Karachi, Pakistan
Document Type
Article
Department
Paediatrics and Child Health
Abstract
Background: The prevalence and incidence of Helicobacter pylori in children in Pakistan is not known.Objectives: To measure the prevalence and age of acquisition of Helicobacter pylori infection/colonization in infants in a peri-urban community in Karachi, Pakistan.SETTING: Field based epidemiologic study in a peri-urban community in Karachi, Pakistan.Methods: Infants aged 1 to 3 months were recruited from a birth cohort from the community. C-urea breath test (C-UBT) was performed on recruitment, and the test was repeated at 2, 3, 6, and 9 months of age.Results: One hundred forty-eight infants were recruited and had C-UBT on 319 occasions over a period of 2 years. Two hundred thirty-one=(72%) tests were positive: 80% (49/61) infants at 1 month of age, 79% (33/42) at 2 month of age, 76% (92/121) at 3 month of age, 58% (37/64) at 6 months of age, and 67% (20/30) at 9 months of age.CONCLUSIONS: The study reveals an early colonization/infection of infants and a high prevalence of Helicobacter pylori in a peri-urban community in Karachi, Pakistan.
Publication (Name of Journal)
Journal of Pediatric Gastroenterology and Nutrition
Recommended Citation
Nizami, S. Q.,
Bhutta, Z. A.,
Weaver, L.,
Preston, T.
(2005). Helicobacter pylori colonization in infants in a peri-urban community in Karachi, Pakistan. Journal of Pediatric Gastroenterology and Nutrition, 41(2), 191-194.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_women_childhealth_paediatr/508