Leishmaniasis - still a diagnostic challenge: An individual participant data systematic review

Authors

Azza Sarfraz, Aga Khan UniversityFollow
Zouina Sarfraz, Fatima Jinnah Medical University, Lahore, Pakistan
Maryyam Liaqat, King Edward Medical University, Lahore, Pakistan
Muhammad Hadi Khan, Pakistan Institute of Medical Sciences, Islamabad, Pakistan
Hafiza Aqsa Abdul Jabbar, Punjab Medical College, Faisalabad, Pakistan
Muhammad Abdullah, Fatima Memorial Medical and Dental College, Lahore, Pakistan

Document Type

Article

Department

Paediatrics and Child Health

Abstract

Leishmania, endemic in nearly half the world's countries, continues to pose significant diagnostic challenges. Our systematic review sought to analyse problems in diagnosis especially in low- to middle-income countries. The average time from symptom onset to diagnosis was 4.5 years. While microscopic detection often failed, polymerase chain reaction showed high sensitivity. Clinical presentations varied significantly, highlighting the complexity of diagnosing leishmaniasis, especially in patients with prolonged disease in non-endemic areas.

Comments

Volume and issue is not provided by the author/publihser.

Publication (Name of Journal)

Tropical Doctor

DOI

doi.org/10.1177/00494755241273086

Recommended Citation

Sarfraz, A., Sarfraz, Z., Liaqat, M., Khan, M. H., Jabbar, H. A., Abdullah, M. (2024). Leishmaniasis - still a diagnostic challenge: An individual participant data systematic review. Tropical Doctor, 1-7.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_women_childhealth_paediatr/1545