Persistent Müllerian duct syndrome.

Authors

Niels-Peter Buchholz, Aga Khan UniversityFollow
Syed Raziuddin Biyabani, The Aga Khan UniversityFollow
MJ Harzig, Aga Khan University
A Ali, Aga Khan University
Zafar Nazir, Agha Khan UniversityFollow
M Nasir Sulaiman, Aga Khan UniversityFollow
Jamsheer J Talati, Aga Khan UniversityFollow

Document Type

Article

Department

Urology

Abstract

Persistent müllerian duct syndrome (PMDS) is a rare form of male pseudohermaphroditism. We present 5 cases with PMDS (2 cases associated with testicular malignancy) and discuss the diagnosis and management. Management strategies of PMDS have changed. Whereas in the past, removal of the müllerian remnants was targeted together with orchidopexy or -ectomy, this is no longer recommended. However, testicles that cannot be descended at an early stage are at a high risk of malignancy and should, therefore, be removed. If this is necessary on both sides, there is the additional problem of lifelong testosterone substitution which requires efficient patient monitoring and good patient compliance. In cases where this cannot be achieved, compromises, such as temporarily delayed orchidectomy, may be considered.

Publication (Name of Journal)

European Urology

Recommended Citation

Buchholz, N., Biyabani, S., Harzig, M., Ali, A., Nazir, Z., Sulaiman, M. N., Talati, J. (1998). Persistent Müllerian duct syndrome.. European Urology, 34(3), 230-232.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_surg_urol/68