Document Type
Article
Department
Orthopaedic Surgery
Abstract
Osteoarthritis is one of the most common degenerative conditions affecting knee joint. As our understanding in the disease pathogenesis is evolving, so do the treatment modalities. One of the postulated mechanisms suggests the production of inflammatory cytokines secondary to repeated micro trauma than in turn lead to cartilage damage overtime. Cartilage being avascular structure has limited potential for repair. Based on this, recent studies have been focusing on stimulating cartilage-healing process by growth factors. This is where platelet-rich plasma comes in to light. Literature is showing promising results of platelet-rich plasma in treating knee osteoarthritis. In this review we have discussed the preparation, composition, classification, uses of platelet-rich plasma as well as evidence for its efficacy and complications.
Publication (Name of Journal)
Orthopedic Reviews
Recommended Citation
Baloch, N.,
Hasan, O.,
Baig, Z.,
Abdullah, U.,
Atif, M.,
Ohuchi, H.
(2019). Use of intraarticular injections of platelet-rich plasma in the treatment of knee osteoarthritis: A review article. Orthopedic Reviews, 11, 161-166.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_surg_orthop/120
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License