CNS manifestations of rosai-dorfman disease

Document Type

Review Article

Department

Surgery; Neurosurgery

Abstract

Rosai-Dorfman disease (RDD) is an abnormal proliferation of histiocytes which manifest classically as bilateral cervical lymphadenopathy and B symptoms. Rarely, it also presents with involvement of other systems. CNS RDD is extremely rare and accounts for 5% of reported cases. The clinical picture is dependent on the area of CNS affected. It is mostly diagnosed on MRI, however, it may be confused with a meningioma, dural based metastases, lymphoma, sarcoidosis, etc. Diagnosis is based on typical histopathological features. The recommended treatment for symptomatic CNS manifestations of RDD is complete surgical resection

Publication (Name of Journal)

Journal of the Pakistan Medical Association

DOI

10.47391/JPMA.25-57

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