United States trends in thrombolysis for older adults with acute ischemic stroke
Objective: Thrombolysis for ischemic stroke has been increasing in the United States. We sought to investigate recent trends in thrombolysis use in older adults.
Methods: A retrospective, observational analysis of hospitalization data from the Nationwide Inpatient Sample (NIS) in 2005-2010 was performed. Older adults (≥65 years) admitted with a primary diagnosis of acute ischemic stroke were included. Trends in the population-based rates of thrombolysis and outcomes from the NIS were evaluated using the Cochran-Armitage test.
Results: Thrombolysis in older adult stroke patients increased from 1.7% to 5.4% (2005-2010; trend PConclusions: Rates of thrombolysis in older adults progressively increased, especially in the oldest old. Increases were largely driven by urban and high volume hospitals.
Clinical Neurology and Neurosurgery
George, B. P.,
Asemota, A. O.,
Dorsey, E. R.,
Haider, A. H.,
Smart, B. J.,
Urrutia, V. C.,
Schneider, E. B.
(2015). United States trends in thrombolysis for older adults with acute ischemic stroke. Clinical Neurology and Neurosurgery, 139, 16-23.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_surg_gen/176