Superficial angiomyxoma of the nasal columella: First reported case of an exceptionally rare presentation

Document Type

Article

Department

Pathology and Laboratory Medicine

Abstract

Superficial angiomyxoma (SAM) is a rare benign mesenchymal tumor, the histological features of which include a myxoid stroma, sparse spindle or stellate cells, thin-walled blood vessels, and a mixed inflammatory infiltrate. Even though it is most commonly found in the trunk, genitalia, and extremities, it is very rare to see it in the nasal cavity. We present the first case of SAM that has been reported to originate from the nasal columella. A 7-year-old boy came in with a five-year history of worsening nasal blockage and a slowly growing, painless nasal tumor. A 4 × 4 cm soft, non-tender lesion originating from the left nasal columella was discovered during clinical examination. A distinct hypodense mass was seen on computed tomography, and there was no sign of nearby bone erosion. With focal CD34 positivity and negative staining for S100, SMA, and desmin, histological examination verified the diagnosis of SAM following complete surgical excision. The patient is still disease-free at the one-month mark. The clinical range of SAM is expanded by this case, which also emphasizes how crucial it is to take this uncommon entity into account when making a differential diagnosis of nasal masses.

Publication (Name of Journal)

Indian Journal of Otolaryngology and Head & Neck Surgery

DOI

10.1007/s12070-025-06284-9

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