"Implementation of a goal-directed care bundle for intracerebral hemorr" by Menglu Ouyang, Anila Anjum et al.
 

Implementation of a goal-directed care bundle for intracerebral hemorrhage: Results of embedded process evaluation in the INTERACT3 trial

Authors

Menglu Ouyang, University of New South Wales, Sydney, Australia
Anila Anjum, Aga Khan UniversityFollow
Francisca Gonzalez Mc Cawley, Facultad de Medicina Clínica Alemana Universidad del Desarrollo, Chile
Mohammad Wasay, Aga Khan UniversityFollow
Lu Ma, West China Hospital, Sichuan University, Chengdu, China
Xin Hu, West China Hospital, Sichuan University, Chengdu, China
Xiaoying Chen, University of New South Wales, Sydney, Australia
Alejandra Malavera, University of New South Wales, Sydney, Australia
Xi Li, West China Hospital, Sichuan University, Chengdu, China
Paula Muñoz Venturelli, University of New South Wales, Sydney, Australia
H Asita de Silva, University of Kelaniya, Kelaniya, Sri Lanka
Nguyen Huy Thang, Stroke Unit, 115 Hospital, Ho Chi Minh City, Vietnam
Kolawole W. Wahab, University of Ilorin & University of Ilorin Teaching Hospital, Ilorin, Nigeria
Jeyaraj D. Pandian, Christian Medical College and Hospital, Ludhiana, India
Octavio M. Pontes-Neto, Ribeirão Preto Medical School, University of São Paulo, Ribeirao Preto, Brazil
Carlos Abanto, National Institute of Neurological Sciences, Lima, Peru
Venessa Cano- Nigenda, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suarez, Mexico City, Mexico
Antonio Arauz, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suarez, Mexico City, Mexico
Chao You, West China Hospital, Sichuan University, Chengdu, Chin
Stephen Jan, Faculty of Medicine, University of New South Wales, Sydney, Australia

Document Type

Article

Department

Medicine; Neurology

Abstract

The third, stepped-wedge, cluster-randomized, Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT3), has shown that a goal-directed multi-faceted Care Bundle incorporating protocols for the management of physiological variables was safe and effective for improving functional recovery in a broad range of patients with acute intracerebral hemorrhage (ICH). The INTERACT3 Care Bundle included time- and target-based protocols for the management of early intensive lowering of systolic blood pressure (SBP, targetNCT03209258) and the Chinese Clinical Trial Registry (ChiCTR-IOC-17011787).

Publication (Name of Journal)

PLOS Global Public Health

DOI

10.1371/journal.pgph.0003711

Share

COinS