Document Type
Case Report
Department
Paediatrics and Child Health (East Africa)
Abstract
Lissencephaly is a rare neuronal migration defect that results in a smooth cerebral surface, mental retardation, and seizures. It is diagnosed primarily by correlating clinical manifestations with MRI findings. We present a case of a 3-year-old girl with developmental delay and seizures. Her first seizure was at 14 months and MRI showed features of lissencephaly and subcortical band heterotopia. Lissencephaly is associated with gene mutations. Treatment focuses on antiseizure meds and physiotherapy to reduce seizures and improve motor skills. This case report highlights the importance of promptly diagnosing the LIS/SBH spectrum to enhance patient outcomes. Timely identification and treatment, such as physiotherapy, can significantly improve the quality of life, especially in resource-limited settings.
Publication (Name of Journal)
Radiology Case Reports
DOI
https://doi.org/10.1016/j.radcr.2024.10.067
Recommended Citation
Ngowi, E.,
Datoo, A.,
Ally, P.,
Salum, H.,
Edward, K.
(2024). Lissencephaly with subcortical band heterotopia in an East African child: A case report. Radiology Case Reports, 20(1), 480-483.
Available at:
https://ecommons.aku.edu/eastafrica_fhs_mc_paediatr_child_health/546
Creative Commons License
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