Acute necrotizing encephalopathy in an infant: A case report
Document Type
Case Report
Department
Medical College (East Africa); Paediatrics and Child Health (East Africa)
Abstract
Acute necrotizing encephalopathy is a rare, severe neurological condition, characterized by symmetrical necrotic brain lesions affecting the thalamus, cerebral white matter, brain stem, and cerebellum. Diagnosis relies on characteristic clinical and radiological features. We describe a 10-month-old female infant presenting with multiple seizures following a brief febrile upper respiratory illness. MRI of the brain showed bilateral symmetrical abnormal signal intensities involving both thalami and caudate nucleus, consistent with ANE. Management of ANE is symptom-related but high-dose steroids and IVIG have been used. This case highlights the importance of recognizing ANE beyond its usual geographic distribution. Early recognition and prompt management help improve outcomes
Publication (Name of Journal)
Radiology Case Reports
DOI
https://doi.org/10.1016/j.radcr.2024.09.149
Recommended Citation
Ngowi, E.,
Juneja, Z.,
Gabone, J.,
Bulimba, M.,
Ebrahim, M.,
Abdallah, Y.
(2024). Acute necrotizing encephalopathy in an infant: A case report. Radiology Case Reports, 20(1), 210-214.
Available at:
https://ecommons.aku.edu/eastafrica_fhs_mc_paediatr_child_health/543
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.