Policies and practices to enhance multi-sectorial collaborations and commercialization of regenerative medicine

Document Type

Book Chapter

Edition

1

ISBN

9781461490623

Editor

Linda F. Hogle

Publication (Name of Journal)

Regenerative Medicine Ethics: Governing Research and Knowledge Practices

Department

Office of the Provost

DOI

https://doi.org/10.1007/978-1-4614-9062-3

Publisher

Springer

City

New York

Abstract

The complexities of the translational pathways for stem cell research point to the need to bolster incentives for collaborative, multinational, multidisciplinary, and multi-sectorial research and development, in particular, harnessing the respective strengths of academic, biotechnology, and pharmaceutical sectors. Collaborations, especially within the pre-competitive environment, are theorized to lead to the more efficient use of resources and knowledge through the reduction of negotiating costs associated with an abundance of intellectual property rights (IPRs), the avoidance of duplicative research within a secretive environment, and the use of standard research tools and methods, supported by repositories for data and materials. This chapter explores models to facilitate such collaborations in stem cell research. The focus is on enablement, through creative management of IPRs, of pre-competitive research with academia at its core. The chapter first provides an overview of the patent landscape in stem cell research. This allows for an understanding of claims that may block follow-on innovation and of areas where numerous overlapping claims make it difficult to define all of the IPRs within a given area and to therefore negotiate freedom to operate. The chapter then describes emerging models in drug discovery and animal model communities that facilitate collaborations in the pre-competitive research environment. Such models range from the establishment of databases and repositories for research reagents to public–private partnerships that harness the capabilities and strengths of multiple sectors. The following section gives examples of such initiatives within stem cell research. The chapter concludes with an analysis of legal barriers to pre-competitive research collaborations, namely, restrictive licensing policies, and discusses incentive structures and best practices for facilitating collaborative, pre-competitive stem cell research.

Comments

This work was published before Tania joined Aga Khan University.

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