Highlights of studies in cardiovascular disease prevention presented at the 2020 American College of Cardiology annual scientific session

Authors

Xiaoming Jia, Baylor College of Medicine, USA.
Mahmoud Al Rifai, Baylor College of Medicine, USA.
Jing Liu, Baylor College of Medicine, USA.
Anandita Agarwala, Washington University School of Medicine in St. Louis, USA.
Martha Gulati, University of Arizona College of Medicine-Phoenix, USA.
Salim S. Virani, Baylor College of Medicine, USA.Follow

Document Type

Article

Department

Office of the Provost; Cardiology

Abstract

Purpose of review: The review highlights selected studies related to cardiovascular disease (CVD) prevention that were presented at the American College of Cardiology 2020 Virtual Scientific Session (ACC.20)/World Cardiology Congress (WCC).
Recent findings: The studies reviewed include clinical trials on the efficacy and safety of alirocumab (Study in Participants with Homozygous Familial Hypercholesterolemia [ODYSSEY HoFH]) and evinacumab in the treatment of homozygous familial hypercholesterolemia (HoFH); Evaluating the Efficacy of E-cigarettes for Smoking Cessation (E3); the use of renal denervation in the treatment of hypertension (SPYRAL HTN-OFF MED PIVOTAL); and the assessment of vericiguat in the treatment of heart failure (A Study of Vericiguat in Participants with Heart Failure with Reduce Ejection Fraction [VICTORIA]). In addition, results from the pooled analysis of phase III trials on inclisiran and secondary analysis examining eicosapentaenoic acid levels and cardiovascular outcomes from the Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial (REDUCE-IT) were included. Finally, we discuss studies examining the use of polygenic risk score with low density lipoprotein cholesterol (LDL-C) and systolic blood pressure (SBP) on lifetime cardiovascular risk. The studies presented at the ACC.20/WCC represent notable contributions in the field of CVD prevention.

Comments

Pagination is not provided by the author/publisher. This work was published before the author joined Aga Khan University.

Publication (Name of Journal)

Current Atherosclerosis Reports

DOI

10.1007/s11883-020-00856-6

Recommended Citation

Jia, X., Al Rifai, M., Liu, J., Agarwala, A., Gulati, M., Virani, S. S. (2020). Highlights of studies in cardiovascular disease prevention presented at the 2020 American College of Cardiology annual scientific session. Current Atherosclerosis Reports, 22(8), 32.
Available at: https://ecommons.aku.edu/provost_office/581