Heartburn's hidden impact: A narrative review exploring gastroesophageal reflux disease (GERD) as a cardiovascular disease risk factor

Authors

Jacob J. Gries, Geisinger Medical Center, USA.
Bing Chen, Geisinger Medical Center, USA.
Salim S. Virani, Aga Khan UniversityFollow
Hafeez Ul Hassan Virk, University Hospitals Cleveland Medical Center, USA.
Hani Jneid, University of Texas Medical Branch, USA.
Chayakrit Krittanawong, NYU School of Medicine, USA.

Document Type

Review Article

Department

Office of the Provost; Cardiology

Abstract

Gastroesophageal reflux disease (GERD) is a very common disease with an estimated 442 million cases worldwide. It is a well-documented independent risk factor for many gastrointestinal pathologies, however, its role in cardiovascular disease (CVD) is unclear, despite its high prevalence in patients with CVD. Although traditionally considered a causative agent of noncardiac chest pain, a common imitator of cardiac chest pain, or an incidentally shared comorbidity in patients with CVD, a number of studies have implicated GERD and its therapies as risk factors for CVD. This narrative review will explore the relationship between GERD and CVD, including medical and mechanical therapeutic approaches for GERD that could potentially impact the incidence, progression, and mortality of CVD.

Comments

Pagination is not provided by the author/publisher.

Publication (Name of Journal)

Journal of Clinical Medicine

DOI

10.3390/jcm12237400

Recommended Citation

Gries, J. J., Chen, B., Virani, S. S., Virk, H. H., Jneid, H., Krittanawong, C. (2023). Heartburn's hidden impact: A narrative review exploring gastroesophageal reflux disease (GERD) as a cardiovascular disease risk factor. Journal of Clinical Medicine, 12(23), 7400.
Available at: https://ecommons.aku.edu/provost_office/503

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.