Non-high-density lipoprotein cholesterol reporting and goal attainment in primary care

Authors

Salim S. Virani, Baylor College of Medicine, United StatesFollow
Degang Wang, Baylor College of Medicine, United States
LeChauncy D. Woodard, Baylor College of Medicine, United States
Supicha S. Chitwood, Baylor College of Medicine, United States
Cassie R. Landrum, Baylor College of Medicine, United States
Franklin J. Zieve, McGuire VA Medical Center, Richmond, VA,
Christie M. Ballantyne, Baylor College of Medicine, United States
Laura A. Petersen, Baylor College of Medicine, United States

Document Type

Article

Department

Cardiology

Abstract

Background: The Adult Treatment Panel III guidelines established non-high-density lipoprotein cholesterol (non-HDL-C) as a secondary treatment target. However, non-HDL-C levels are not reported on standard lipid panels by many hospital-based and/or commercial biochemical laboratories.
Objective: We determined whether reporting non-HDL-C was associated with improved non-HDL-C goal attainment.
Methods: We identified patients with cardiovascular disease (CVD) and/or diabetes receiving care within the Veterans Health Administration. We matched a facility that reported non-HDL-C levels on lipid panels (3994 CVD and 5108 diabetes patients) to a facility with similar size, patient complexity, and academic mission that did not report non-HDL-C (4269 CVD and 6591 diabetes patients). We performed patient-level analysis to assess differences in non-HDL-C from baseline to the most recent lipid panel at these facilities.
Results: Baseline non-HDL-C levels for CVD patients were 114 mg/dL and 107 mg/dL at the reporting and nonreporting facilities, respectively. At 2.3-year follow-up, non-HDL-C levels decreased at both facilities but by a greater amount at the reporting facility (-11 mg/dL vs -3 mg/dL at the nonreporting facility, P < .001). Results remained significant (P < .001) after we adjusted for patient's age, race, gender, illness burden, history of diabetes, hypertension, medication adherence, statin use, number of lipid panels, and number of primary care visits between baseline and follow-up. Reductions were greater among CVD patients with triglycerides ≥200 mg/dL (-25 mg/dL vs -16 mg/dL at the respective facilities, P = .004). Results were similar in diabetes patients. Reporting was also associated with greater proportions of patients meeting non-HDL-C treatment goal of <130 mg/dL.
Conclusion: Non-HDL-C reporting could improve non-HDL-C goal attainment.

Comments

This work was published before the author joined Aga Khan University.

Publication (Name of Journal)

Journal of Clinical Lipidology

Recommended Citation

Virani, S. S., Wang, D., Woodard, L. D., Chitwood, S. S., Landrum, C. R., Zieve, F. J., Ballantyne, C. M., Petersen, L. A. (2012). Non-high-density lipoprotein cholesterol reporting and goal attainment in primary care. Journal of Clinical Lipidology, 6(6), 545-552.
Available at: https://ecommons.aku.edu/provost_office/246