Novel therapies for treating familial hypercholesterolemia

Authors

Salman J. Bandeali, St. Luke’s Episcopal Hospital, United States
Jad Daye, Baylor College of Medicine, United States
Salim S. Virani, Baylor College of Medicine, United StatesFollow

Document Type

Article

Department

Cardiology; Office of the Provost

Abstract

Familial hypercholesterolemia is an inherited disorder associated with early accelerated atherosclerosis with morbidity and mortality resulting from premature cardiovascular disease. Affected individuals have extreme elevations in low-density lipoprotein cholesterol levels. Patients usually do not achieve target reductions in cholesterol levels with conventional antihyperlipidemic pharmacotherapy. This unmet need has resulted in the recent development and approval of novel therapies targeting different cholesterol pathways. This article briefly summarizes familial hypercholesterolemia and then discusses the newer pharmacotherapies available in the management of familial hypercholesterolemia.

Comments

Pagination are not provided by the author/publisher. This work was published before the author joined Aga Khan University.

Publication (Name of Journal)

Current Atherosclerosis Reports

DOI

10.1007/s11883-013-0382-0

Recommended Citation

Bandeali, S. J., Daye, J., Virani, S. S. (2014). Novel therapies for treating familial hypercholesterolemia. Current Atherosclerosis Reports, 16(1), 382.
Available at: https://ecommons.aku.edu/provost_office/218