Document Type
Article
Department
Paediatrics and Child Health
Abstract
The 10-valent pneumococcal vaccine was introduced in Pakistan's Expanded Program on Immunization (EPI) in 2013 as a 3 + 0 schedule without catchup. We conducted three annual cross-sectional surveys from 2014-2016 to measure vaccine-type (VT) carriage in infants from a rural part of Pakistan. Nasopharyngeal specimens were collected by random sampling of infants from two union councils of Matiari. Samples were then transported to the Infectious Disease Research Laboratory (IDRL) at the Aga Khan University within 6-8 h of collection. Serotypes were established using sequential multiplex PCR. Of the 665 children enrolled across three surveys, 547 were culture-positive for pneumococcus. VT carriage decreased from 21.8% in 2014 to 12.7% in 2016 (p-value for trend
Publication (Name of Journal)
Vaccines
Recommended Citation
Shahid, S.,
Khan, A.,
Nisar, M. I.,
Khalid, F.,
Qazi, M. F.,
Ahmed, S.,
Kabir, F.,
Hotwani, A.,
Muneer, S.,
Ali, S.,
Zaidi, A.,
Jehan, F.
(2022). Pneumococcal carriage in infants post-PCV10 introduction in Pakistan: Results from serial cross-sectional surveys. Vaccines, 10(6), 971.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_women_childhealth_paediatr/1207
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Included in
Influenza Humans Commons, Influenza Virus Vaccines Commons, Maternal and Child Health Commons, Pediatrics Commons, Virus Diseases Commons
Comments
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