Title

Antibodies to adhesion molecules for immunotherapy of brain tumors

Document Type

Book Chapter

Department

Neurosurgery

Abstract

The major morbidity of gliomas lies in their infiltrative growth. The cell biology of invading neoplastic cells is similar to that of migrating fetal cells. Several adhesion molecules that are downregulated after completion of fetal brain development are re-expressed in neoplasms of the nervous system. The crucial role played by adhesion molecules during neural development is repeated during glioma invasion (1).

Publication

Brain Tumor Immunotherapy

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