Antibodies to adhesion molecules for immunotherapy of brain tumors
The major morbidity of gliomas lies in their infiltrative growth. The cell biology of invading neoplastic cells is similar to that of migrating fetal cells. Several adhesion molecules that are downregulated after completion of fetal brain development are re-expressed in neoplasms of the nervous system. The crucial role played by adhesion molecules during neural development is repeated during glioma invasion (1).
Publication ( Name of Journal)
Brain Tumor Immunotherapy
(2001). Antibodies to adhesion molecules for immunotherapy of brain tumors. Brain Tumor Immunotherapy, 249-270.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_surg_neurosurg/83