Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: A case series
Document Type
Case Report
Department
Radiation Oncology; Haematology/Oncology
Abstract
A retrospective review was conducted In Aga Khan University from January 2013-December 2020 for patients who received Total Skin Electron Beam Therapy (TSEBT) on the management of Mycosis Fungoides (MF). The clinical response rate and disease-free interval (DFI) was evaluated for three patients. All of the patients received a 3600 cGy dose of radiation. Clinical complete remission (cCR) was observed in two out of three patients, while one patient showed clinical partial response. Following the cCR to TSEBT, the DFI of the first patient with stage 1B lasted 30 months, while the second patient with stage IIB remained disease free for five months. TSEBT is an effective treatment for MF disease. It can thus be expected that patients with limited disease in the early stage can acquire a cCR with a longer DFI. The clinical outcomes of our study show concordance with the literature. The patients who had extensive (T3) skin involvement and had refractory diseases showed lower DFI with radiation.
Publication (Name of Journal)
Journal of the Pakistan Medical Association
DOI
10.47391/JPMA.3784
Recommended Citation
Abrar, S.,
Qureshi, B. M.,
Hafiz, A.,
Ali, N.,
Khan, A. H.,
Abbasi, A. N.
(2022). Total skin electron beam therapy (TSEBT) in management of mycosis fungoides: A case series. Journal of the Pakistan Medical Association, 72(6), 1208-1210.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_radiat_oncol/128