Involvement of bone marrow with intravascular large B-cell lymphoma.

Document Type

Article

Department

Radiation Oncology

Abstract

Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of extranodal large B-cell lymphoma characterized by a selective proliferation of lymphoma cells within the lumina of vessels. We report a case of an 86-year-old man who presented with fever, shortness of breath and altered mental status. The diagnosis of IVLBCL was confirmed on a bone trephine biopsy that revealed positivity of CD20 and PAX5 immunohistochemical staining of lymphoma cells confined within the lumina of vessels. The Patient had a rapidly deteriorating clinical course with a fatal outcome even before the specific treatment for the underlying disease was commenced.

Publication (Name of Journal)

Hematology/Oncology and Stem Cell Therapy

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