Association of bipolar I disorder with obsessive compulsive disorder: A clinical study from Pakistan
Document Type
Article
Department
Psychiatry
Abstract
Background: The association and/or comorbidity of bipolar I disorder I (BD I) with obsessive compulsive disorder (OCD) is discussed in the literature. This association is under-recognized in Pakistan causing management problems. This is the first study reporting this association in Pakistan.
Method: Retrospective data collection of 500 patients consecutively diagnosed with BD I according to DSM IV-TR was done in inpatient and outpatient settings at a tertiary care setting in Karachi, Pakistan; 469 patients who fulfilled the criteria were included in the study. Patients with BD I with and without OCD were compared for demographics, presenting symptoms, duration of disease, differences in treatment, and other clinical variables.
Results: 35 (7.5%) of the 469 patients had OCD along with BD I, with more than half having bipolar as the first diagnosis. A majority of the BD I−OCD patients had OCD symptoms during manic phase or in remission, with contamination as the main theme. The BD I−OCD group had a lower level of education, higher divorce rates, a higher incidence of OCD, as well as BD in the family, longer duration of illness, and fewer medical comorbidities.
Limitations: This is a retrospective study with patients from both inpatient and outpatient settings from a tertiary care hospital.
Conclusion: The association of BD I with OCD needs to be recognized by clinicians, as presentation may be different in this group especially in contextualized settings in Pakistan, where OCD or OCD-like symptoms may be related to BD itself. This finding has important diagnostic and management implications.
Publication (Name of Journal)
Neurology, Psychiatry and Brain Research
Recommended Citation
Khan, Q.,
Younus, S.,
Hasan, H.,
Zaman, M.
(2019). Association of bipolar I disorder with obsessive compulsive disorder: A clinical study from Pakistan. Neurology, Psychiatry and Brain Research, 33, 89-92.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_psychiatry/119
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