Pathology and Microbiology; Haematology/Oncology; Obstetrics and Gynaecology
Objective: To analyze the chromosomal abnormalities in couples with history of recurrent abortions.
Design: Retrospective study.
Setting: Cytogenetic section, Department of Pathology at the Aga Khan University Hospital. Karachi, Pakistan. Patients: Three hundred couples with history of recurrent abortions. Main outcome measure: Structural chromosomal abnormalities in carrier couples.
Results: G-banded chromosomes were analyzed from both partners of 300 couples who had had two or more spontaneous abortions. Sixteen (5.3%) couples showed a chromosomal aberration in one of the partners. Seven translocations, 5 inversions, 2 deletions and 2 sex chromosomal abnormalities were identified. There was an increase in structural aberations, which was not significantly different from that reported worldwide. a primary tool in the evaluation of couples with repetitive.
Conclusion:Chromosomal analysis is advocated as fetal wastage
Journal of Pakistan Medical Association
(2003). Chromosomal abnormalities as a cause of recurrent abortions: a hospital experience. Journal of Pakistan Medical Association, 53, 117.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/566