Document Type
Article
Department
Pathology and Microbiology; Haematology/Oncology; Obstetrics and Gynaecology
Abstract
Objective: To analyze the chromosomal abnormalities in couples with history of recurrent abortions.
Design: Retrospective study.
Setting: Cytogenetic section, Department of Pathology at the Aga Khan University Hospital. Karachi, Pakistan. Patients: Three hundred couples with history of recurrent abortions. Main outcome measure: Structural chromosomal abnormalities in carrier couples.
Results: G-banded chromosomes were analyzed from both partners of 300 couples who had had two or more spontaneous abortions. Sixteen (5.3%) couples showed a chromosomal aberration in one of the partners. Seven translocations, 5 inversions, 2 deletions and 2 sex chromosomal abnormalities were identified. There was an increase in structural aberations, which was not significantly different from that reported worldwide. a primary tool in the evaluation of couples with repetitive.
Conclusion:Chromosomal analysis is advocated as fetal wastage
Publication (Name of Journal)
Journal of Pakistan Medical Association
Recommended Citation
Azim, M.,
Khan, A.,
Khilji, Z.,
Pal, J.,
Khurshid, M.
(2003). Chromosomal abnormalities as a cause of recurrent abortions: a hospital experience. Journal of Pakistan Medical Association, 53, 117.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/566