Performance evaluation of ion exchange and affinity chromatography for HbA(1c) estimation in diabetic patients with HbD: A study of 129 samples
Document Type
Article
Department
Pathology and Microbiology
Abstract
Objectives:
To compare ion exchange and boronate affinity chromatography for HbA(1c) estimation in Patients with type I and II diabetes having hemoglobin D. Design And
Methods:
Systems based on ion exchange and boronate affinity chromatography were evaluated and compared for their performance forHbA(1c) estimation in Patients with homozygous and heterozygous D disease.
Results:
Boronate affinity chromatography shows least interference by HbD in heterozygous as well as homozygous diabetic Patients for HbA(1c) estimation.
Conclusion:
The use of boronate affinity chromatography was found to be helpful in evaluating glycemic control in diabetic subjects with HbD.
Publication (Name of Journal)
Clinical Biochemistry
Recommended Citation
Moiz, B.,
Hashmi, M.,
Sadaf, S.
(2008). Performance evaluation of ion exchange and affinity chromatography for HbA(1c) estimation in diabetic patients with HbD: A study of 129 samples. Clinical Biochemistry, 41(14-15), 1204-1210.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/157
