Quality indicators for critical international normalized ratio measurements in a hemostatic laboratory
Document Type
Article
Department
Pathology and Laboratory Medicine
Abstract
Objective: This study aimed at reviewing the quality indicators for reporting critical international normalized ratio (INR) in a coagulation laboratory.DESIGN AND Methods: This is a retrospective study conducted at Aga Khan University Hospital, hemostatic laboratory from February 2010 till January 2011. Critical INR was defined as ≥5.0. All critical INRs were rechecked and results were communicated to the doctor or patient. Two quality indicators monitored were % of results communicated to the patient/doctor and % of results that remained critical after re-testing.Results: During the study period, a total of 59,980 INRs were reported. Of these 376 or 0.6% were critical. Successful communication of critical results to the doctor or patient was achieved in 275/376 (73.1%). Overall 353 or 94% (343 initial and 10 re-draw) samples had critical INR on repetition. Twenty five patients of the 240 warfarinized patients with critical INR had mild bleeding. No life threatening bleeding was observed in any patient.CONCLUSION: We observed poor communication for notifying critical INR results during the study period. Routine repeat analysis of critical INR did not alter results in majority of samples. The study assisted in improving communication in subsequent years. Further work is needed to establish evidence based upper and lower cutoff of critical INR. Effect of replicate analysis on turnaround time and accuracy of results needs evaluation.
Publication (Name of Journal)
Clinical Biochemistry
Recommended Citation
Hussain, S.,
Moiz, B.,
Afaq, B.
(2015). Quality indicators for critical international normalized ratio measurements in a hemostatic laboratory. Clinical Biochemistry, 48(2018-07-08), 483-484.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_pathol_microbiol/1094