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Submissions from 2018

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Emergence of an extensively drug-resistant salmonella enterica serovar typhi clone harboring a promiscuous plasmid encoding resistance to fluoroquinolones and third-generation cephalosporins, Rumina Hasan, Sadia Shakoor, Farah Naz Farid, Dania Khalid Saeed, Ghazala Shaheen, Shahida Qureshi, Mohammad Tahir Yousafzai, Muhammad Khalid Salim, Zahra Hasan, Elizabeth J. Klemma, Andrew J. Page, Kim Judge, Vanessa K. Wong, Timothy J. Dallman, Satheesh Nair, Stephen Baker, and Gordon Dougan

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Integrating tuberculosis and antimicrobial resistance control programmes, Rumina Hasan, Sadia Shakoor, Johanna Hanefeld, and Mishal Khan

Relationship of serum procalcitonin, c-reactive protein, and lactic acid to organ failure and outcome in critically Ill pediatric population, Lena Jafri, Imran Siddiqui, Qalab Abbas, Ahmed Raheem Buksh, and Anwar Ul Haque

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Human west nile virus disease outbreak in Pakistan, 2015–2016, E. Khan, Kelli L. Barr, Joveria Farooqi, Dhani Prakoso, Alizae Abbas, Zain Y. Khan, Shanze Ashi, Kehkashan Imtiaz, Z Aziz, and Faisal Malik

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Neurological involvement associated with plasmodium vivax malaria from Pakistan, Yousaf Abdullah Khan, Usman Hameed Mian, Najia Karim Ghanchi, Ali Bin Sarwar Zubairi, and Mohammad Asim Beg

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Global distribution of invasive serotype 35D streptococcus pneumoniae post-PCV13 introduction, Stephanie W. Lo, Rebecca A. Gladstone, Andries J. van Tonder, Paulina A. Hawkins, Brenda Kwambana Adams, Jennifer E. Cornick, Shabir A. Madhi, Susan A. Nzenze, Mignon du Plessis, Rama Kandasamy, Philip E. Carter, and Sadia Shakoor

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Cold agglutinins in peripheral blood with atypical cells with an owl-eye appearance in bone trephine, Ayesha Majeed Memon and Farheen Karim

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Spoon nails: still seen in today's world, Bushra Moiz

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Fulminant hemolysis in glucose-6-phosphate dehydrogenase deficiency, Bushra Moiz and Sidra Asad Ali

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Prospective comparison of point-of-care device and standard analyzer for monitoring of international normalized ratio in outpatient oral anticoagulant clinic, Bushra Moiz, Ahmed Raheem, Anila Rashid, Muhammad Hasan, and Lena Jafri

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Frequency of macroprolactin in hyperprolactinemia, Noreen Abbas Sherazi, Mirza Zain Baig, and Aysha Habib Khan

Pattern of bone marrow involvement in non hodgkin's lymphoma classified according to WHO classification: report of a developing country Pakistan, Sadia Sultan, Naseer Baloch, Zeeshan Ansar Ahmed, Syed Mohammad Irfan, and Saira Parveen

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Abdominopelvic and retroperitoneal low-grade fibromyxoid sarcoma: a clinicopathologic study of 13 cases, Nasir Ud Din, Zubair Ahmad, Riyam Zreik, Andrew Horvai, Andrew L. Folpe, and Karen Fritchie

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Ectopic enterobius vermicularis Iinfestation; an extremely rare cause of mesenteric lymphadenopathy mimicking tuberculous lymphadenitis, Summaya Zafar, Muhammad Usman, and Zubair Ahmad

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Genetic sequencing for surveillance of drug resistance in tuberculosis in highly endemic countries: a multi-country population-based surveillance study, Matteo Zignol MD, Andrea Maurizio Cabibbe, Anna S. Dean, Philippe Glaziou, Natavan Alikhanova, Cecilia Ama, Sönke Andres, Anna Barbova, Rumina Hasan, and Zahra Hasan

Submissions from 2017

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Evaluation of 'CKD-EPI Pakistan' equation for estimated glomerular filtration rate (eGFR): a comparison of eGFR prediction equations in Pakistani population, Sibtain Ahmed, Lena Jafri, and Ayesha Habib Khan

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Case series of naegleria fowleri primary ameobic meningoencephalitis from Karachi, Pakistan, Zeeshan Ansar, Bushra Jamil, Azra Samreen, E. Khan, Zahra Hasan, Najia Karim Ghanchi, and Afia Zafar

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Increasing usage of rapid diagnostics for dengue virus detection in Pakistan, Zahra Hasan, Saher Razzak, Muhammad Farhan, Maryam Rahim, Nazneen Islam, Azra Samreen, and E. Khan

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Evaluation of Xpert MTB/RIF testing for rapid diagnosis of childhood pulmonary tuberculosis in children by Xpert MTB/RIF testing of stool samples in a low resource setting, Zahra Hasan, Sadia Shakoor, Fehmina Arif, Aisha Mehnaz, Alnoor Akber, Marium Haider, Akber Kanji, and Rumina Hasan

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Serious fungal infections in Pakistan, Kauser Jabeen, Joveria Farooqi, Afia Zafar, Sajjad Mirza, and D Denning

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Transfusion transmitted dengue: one donor infects two patients, Farheen Mahar Karim, Nadia Nasir, and Bushra Moiz

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High burden of subclinical lead toxicity after phase out of lead from petroleum in Pakistan, Hafsa Majid, Aysha Habib, Nadeem Ullah Khan, Imran Siddiqui, Farooq Ghani, and Lena Jafri

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High burden of subclinical lead toxicity after phase out of lead from petroleum in Pakistan, Hafsa Majid, Aysha Habib, Nadeem Ullah Khan, Imran Siddiqui, Farooq Ghani, and Lena Jafri

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Frequency of G6PD mediterranean in individuals with and without malaria in southern Pakistan, Bushra Moiz, Haroon Muhammad Arshad, Ahmed Raheem Raheem, Hasan Hayat, Najia Karim Ghanchi, and M Asim Beg

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Role of mesenchymal stem cells in acquisition of metaplasia in AKU-BC42 breast metaplastic carcinoma cell line, Nazia Riaz, Sadia Habib, Azhar Hussain, and El Nasir Lalani

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Readiness for antimicrobial resistance (AMR) surveillance in Pakistan; a model for laboratory strengthening, Dania Khalid Saeed, Rumina Hasan, Mahwish Naim, Afia Zafar, E. Khan, Kauser Jabeen, Seema Irfan, Imran Ahmed, Mohammad Zeeshan, Zabin Wajidali, Joveria Farooqi, Sadia Shakoor, Abdul Chagla, and Jason Rao

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Readiness for antimicrobial resistance (AMR) surveillance in Pakistan; a model for laboratory strengthening, Dania Khalid Saeed, Rumina Hasan, Mahwish Naim, Afia Zafar, E. Khan, Kauser Jabeen, Seema Irfan, Imran Ahmed, Mohammad Zeeshan, Zabin Wajidali, Joveria Farooqi, Sadia Shakoor, Abdul Chagla, and Jason Rao

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Readiness for antimicrobial resistance (AMR) surveillance in Pakistan; a model for laboratory strengthening, Dania Khalid Saeed, Rumina Hasan, Mahwish Naim, Afia Zafar, Erum Khan, Kauser Jabeen, Seema Irfan, Imran Ahmed, Mohammad Zeeshan, Zabin Wajidali, Joveria Farooqi, Sadia Shakoor, Abdul Chagla, and Jason Roy

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Anaplastic lymphoma kinase protein positive diffuse large B cell lymphoma; a developing world experience, Huzaifah Sala, Nasir Ud Din, tariq moatter, Naila Kayani, and Arsalan Ahmed

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Susceptibility pattern of methicillin resistant staphylococcus aureus to vancomycin and other alternate agents: report from a private sector hospital laboratory, Faryal Saleem, 1 Naima Fasih, and Afia Zafar

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Hybrid peripheral nerve sheath tumors: report of five cases and detailed review of literature, Nasir Ud Din, Zubair Ahmad, Jamshid Abdul Ghafar, and Rashida Ahmed

Submissions from 2016

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Fibroblast growth factor 23 (FGF23) levels, phosphate Intake and its association with Indices of renal handling of phosphate in healthy volunteers, Noreen Abbas, Aysha Habib Khan, Farooq Ghani, and Imran Siddiqui

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Assessment of WT1 expression as a marker of treatment outcome in karyotype normal acute myeloid leukemia patients in Pakistan, Zeeshan Ansar Ahmed, Muhammad Shariq Shaikh, and Tariq Moatter

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Autologous transplant in lymphomas in current era of immunotherapy, Natasha Ali and Mohammad Khurshid

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Effect of steroids on inflammatory markers and clinical parameters in congenital open heart surgery: a randomised controlled trial, Muhammad M. Amanullah, Mohammad Hamid, Hashim M. Hanif, Marium Muzaffar, Maria T. Siddiqui, Fatima Adhi, Khabir Ahmad, Shahjahan Khan, and Zahra Hasan

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Fast dissemination of new HIV-1 CRF02/A1 recombinants in Pakistan, Yue Chen, Bhavna Hora, Todd DeMarco, Sharaf Ali Shah, Manzoor Ahmed, Ana M. Sanchez, Chang Su, Meredith Carter, Mars Stone, Rumina Hasan, Zahra Hasan, Michael P. Busch, Thomas N. Denny, and Feng Gao

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Naegleria fowleri meningoencephalitis associated with public water supply, Pakistan, 2014, Najia Ghanchi, Erum Khan, Azam Khan, Wali Muhammad, Faisal Riaz Malik, and Afia Zafar

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Primary angiosarcoma of breast, Saroona Haroon, Naveen Faridi, and Faisal Rashid Lodhi

Effective testing for pulmonary tuberculosis using Xpert MTB/RIF assay for stool specimens in immunocompetent Pakistani children, Zahra Hasan, Fehmina Arif, Sadia Shakoor, Aisha Mehnaz, Alnoor Akber, Akbar Kanji, Mussarat Ashraf, and Rumina Hasan

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Massive pulmonary embolism presenting as seizures, Shahrukh Hashmani, Fateh Ali Tipoo Sultan, Murtaza Kazmi, and Amammarah Yasmeen

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Genomic diversity of EPEC associated with clinical presentations of differing severity., Tracy H. Hazen, Michael S. Donnenberg, Sandra Panchalingam, Martin Antonio, Anowar Hossain, Inacio Mandomando, John Benjamin Ochieng, Thandavarayan Ramamurthy, Boubou Tamboura, Shahida Qureshi, Farheen Quadri, Anita Zaidi, Karen L. Kotloff, Myron M. Levine, Eileen M. Barry, James B. Kaper, David A. Rasko, and James P. Nataro

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Young man with dyspnoea for 6 months; presenting with subacute tracheal obstruction due to leiomyoma, Farah Idress, Saulat Fatimi, and Shahid Pervez

Assessment of diabetes among tuberculosis patients presenting at a tertiary care facility in Pakistan, Muhammad Irfan, Naseem Salahuddin, Qamar Masood, Owais Ahmed, Umme Salama Moosajee, and Zahra Hasan

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Antimicrobial resistance and Neisseria gonorrhoeae multiantigen sequence typing (NG-MAST) genotypes in N. gonorrhoeae during 2012-2014 in Karachi, Pakistan, Kausar Jabeen, Bhawan Mal P, Khan E, Chandio S, Jacobsson S, and Unemo M

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Agreement of direct antifungal susceptibility testing from positive blood culture bottles with the conventional method for candida species, Kauser Jabeen, Haresh Kumar, Joveria Farooqi, Raunaq Mehboob, Mary E. Brandt, and Afia Zafar

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Diagnostic accuracy of anti-endomysial antibody in celiac disease, Arslaan Javaeed, Walayat Shah, Saaniya Khan Gauri, and Rizwan Akhtar

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Alternate efflux pump mechanism may contribute to drug resistance in extensively drug-resistant isolates of mycobacterium tuberculosis, Akbar Kanji, Rumina Hasan, Ambreen Zaver, Asho Ali, Kehkashan Imtiaz, Mussarat Ashraf, Taane G. Clark, Ruth Mc Nerney, Samreen Shafiq, and Zahra Hasan

Increased expression of efflux pump genes in extensively drug-resistant isolates of mycobacterium tuberculosis, Akbar Kanji, Rumina Hasan, Ying Zhang, Wanliang Shi, Kehkashan Imtiaz, Kiran Iqbal, Samreen Shafiq, and Zahra Hasan

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Nigella sativa oil reduces extrapyramidal symptoms (EPS)-like behavior in haloperidol-treated rats, Tafheem Malik, Sheema H Hasan, Shahid Pervez, and Darakhshan Haleem

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Nigella sativa oil reduces extrapyramidal symptoms (EPS)-like behavior in haloperidol-treated rats, Tafheem Malik, Sheema Hasan, Shahid Pervez, Tasneem Fatima, and Darakhshan Jabeen Haleem

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Nigella sativa oil Reduces extrapyramidal symptoms (EPS)-like behavior in haloperidol-treated rats, Tafheem Malik, Sheema Hasan, Shahid Pervez, Tasneem Fatima, and Darakhshan Jabeen Haleem

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Antimicrobial Susceptibility Testing of Neisseria Gonorrhoeae Isolates in Pakistan by Etest Compared to Calibrated Dichotomous Sensitivity and Clinical Laboratory Standards Institute Disc Diffusion Techniques., Pushpa Bhawan Mal, Kauser Jabeen, Joveria Farooqi, Magnus Unemo, and Erum Khan

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Increased mycobacterium tuberculosis antigen-induced gene expression of interferon-gamma, tumor necrosis factor alpha and interleukin-6 in patients with diabetes, Kiran I. Masood, Muhammad Irfan, Qamar Masood, Bushra Jamil, Shoaib Rao, Maryam Rahim, and Zahra Hasan

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Carotid intima media thickness evaluation by ultrasound comparison amongst healthy, diabetic and hypertensive Pakistani patients, Waseem Mirza, Vaqar Bari, Mirza Kazim, Kainat Fatima, Zafar Sajjad, Aziz Jiwani, Nadeem Ahmad, Mubashir Arain, and Arif Ali

Bone turnover markers for osteoporosis status assessment at baseline in postmenopausal Pakistani females, Syed Talha Naeem, Ahmed Raheem, Imran Siddiqui, Riffat Hussain, Farooq Ghani, and Aysha Habib

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Adenoid cystic carcinoma of breast: clinicopathologic study of seven cases, Raabia Nizamuddin, Nasir Ud Din, Romana Idress, and Naila Kayani

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Three siblings with familial non-medullary thyroid carcinoma: a case series, Muhammad Owais Rashid; Naeemul Haq; Saad Farooq; Zareen Kiran,; Sabeehuddin Siddique; Shahid Pervez; and Najmul Islam

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Lack of androgen receptor expression correlates with high expression of ALDH1 and poor overall and 5-year disease free survival in patients with invasive breast cancer, Nazia Riaz, Romana Idress, Sadia Habib, Syed Zulfiqar Naqvi, Shaista Masood Khan, Anwar Ali Siddiqui, and El Nasir Lalani

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Clinical utility of immature platelet fraction - an advanced parameter in laboratory hematology, Muhammad Shariq Shaikh and Sidra Asad Ali

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Clinico-pathological profile and outcomes of patients with polycythaemia vera, essential thrombocythaemia and idiopathic myelofibrosis: a tertiary care center experience from southern Pakistan, Muhammad Shariq Shaikh, Mohammad Usman Shaikh, Salman Naseem Adil, Mohammad Khurshid, and Zeeshan Ansar Ahmed

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Post-chemotherapy neuroblastoma-like differentiation in ewing sarcoma of humerus: report of a rare case with review of literature, Nasir Ud Din, Amna Qasim, Zubair Ahmad, and Sheema H Hasan

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Population-based resistance of mycobacterium tuberculosis isolates to pyrazinamide and fluoroquinolones: results from a multicountry surveillance project, Matteo Zignol, Anna S. Dean, Sönke Andres, Natavan Alikhanova, Andrea Maurizio Cabibbe, Daniela Maria Cirillo, Andrei Dadu, Andries Dreyer, Michèle Driesen, Christopher Gilpin, Rumina Rumina, Zahra Hasan, Sven Hoffner, Ashaque Husain, Alamdar Hussain, Nazir Ismail, Mostofa Kamal, Mikael Mansjö, Lindiwe Mvusi, Stefan Niemann, Shaheed V. Omar, Ejaz Qadeer, Leen Rigouts, Sabine Ruesch Gerdes, Marco Schito, Mehriban Seyfaddinova, Alena Skrahina, Sabira Tahseen, William A. Wells, Ya Diul Mukadi, Michael Kimerling, Katherine Floyd, Karin Weyer, and Mario C. Raviglione

Submissions from 2015

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Environmental and food allergens reactivity and its association with total IgE, age and gender in Karachi, Pakistan, Noreen Abbas, Ahmed Raheem, and Farooq Ghani

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Whole genome sequencing based characterization of extensively drug-resistant mycobacterium tuberculosis isolates from Pakistan, Asho Ali, Zahra Hasan, Ruth McNerney, Kim Mallard, Grant Hill Cawthorne, Francesc Coll, Mridul Nair, Arnab Pain, Taane G. Clark, and Rumina Hasan

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A rare haemoglobin variant identified as k woolwich in a Pakistani male, Sidra Asad Ali and Natasha Ali

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Symptomatic surgically treated non-neoplastic cysts of the central nervous system: a clinicopathological study from Pakistan, Nasir Ud Din, Huma Arshad, Zubair Ahmad, Sheema H Hasan, and Mohammad Ehsan Bar

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Differential expression of Cytokeratin 13 in Non-Neoplastic, Dysplastic and Neoplastic oral Mucosa in a high risk Pakistani population, Sanniya Farrukh, Serajuddaula Syed, and Shahid Pervez

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Consensus report: preventive measures for crimean-congo hemorrhagic fever during Eid-al-Adha festival, Hakan Hakan Leblebicioglu, Mustafa Sunbu, Ziad A. Memish, Jaffar A. Al-Tawfiq, Hurrem Bodur, Aykut Ozkul, Ali Gucukoglu, Sadegh Chinikar, and Zahra Hasan

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An audit of clinical laboratory data of 25OHD at Aga Khan University as reflecting Vitamin D deficiency in Pakistan, Sidra Hassan, Syeda Maria Muzammil, Lena Jafri, and Aysha Habib Khan

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Monitoring and reporting transfusion reactions as a quality indicator – a clinical audit, Shabneez Hussain, Bushra Moiz, Fatima Azra Ausat, and Mohammad Khurshid

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Suppressor of Cytokine signaling-1 and Chemokine (C-X-C Motif) receptor 3 expressions are associated with caseous Necrosis in Granulomas from patients with Tuberculous Lymphadenitis, Masood K. I, Shahid Pervez, Rottenberg M. E, Umar B, and Hasan Z

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Evaluating laboratory performance in external quality assessment schemes for urine organic acids by GCMS, Lena Jafri, Noreen Sherazi, Azeema Jamil, Farhat Jehan, Rakshanda Mehar, Nasir Yousufzai, Bushra Afroze, and Aysha Habib

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Application of Sigma Metrics for the Assessment of Quality Assurance for Plasma Amino Acid Analysis in Biochemical Genetics Laboratory in Pakistan, Lena Jafri, Nasir Yousufzai, Noreen Sherazi, Azeema Jamil, Rakshanda Mahar, Farhat Jahan, Bushra Afroze, and Aysha Habib Khan

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Characterization of genomic variations in SNPs of PE_PGRS genes reveals deletions and insertions in extensively drug resistant (XDR) M. tuberculosis strains from Pakistan., Akber Kanji; Zahra Hasan; Ruth Mcnerney; Mridul Nair; Asho Ali; Kim Mallard; Taane G. Clark; Ambreen Zaver; Sana Jafri,; and Rumina Hasan

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Rhesus and kell phenotyping of voluntary blood donors: foundation of a donor data bank, Farheen Karim, Bushra Moiz, Fahmida Jan Muhammad, Fatima Ausat, and Mohammad Khurshid

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Error identification in a high-volume Clinical Chemistry laboratory: five-year experience, Jafri L, Aysha Habib Khan, Ghani F, Shakeel S, Raheem A, and Siddiqui I

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R990G Polymorphism of calcium sensing receptor gene Is associated with high Parathyroid Hormone levels in subjects with Vitamin D deficiency: a cross-sectional study, Hafsa Majid, Aysha Habib Khan, and Tariq Moatter

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Looks can be deceiving: adrenal Teratoma causing diagnostic difficulty, Nadeem M, Ather M. H, Sulaiman M. N, and Shahid Pervez

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Ki-67 labeling indices in 'Classic' versus 'Blastoid' Mantle Cell Lymphomas--proposed cutoff values for routine diagnostic workup, Shahid Pervez and Haroon S. Awan D

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P064 expression of Tumor initiating markers in Metaplastic Carcinoma of the breast, N. Riaz, Z. Naqvi, R. Idress, S M. Khan, A A. Siddiqui, and El-Nasir Lalani

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Cryptococcus neoformans and streptococcus pneumoniae co-infection in post-traumatic meningitis in a patient with unknown HIV status, Faryal Saleem, Naima Fasih, and Afia Zafar

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A T-Cell/Histiocyte-rich large B-cell Lymphoma involving only the bone marrow, Maria Shafiq and Farheen Karim

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Establishing quality control values for hematology parameters: an insight, Muhammad Shariq Shaikh

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Iron chelation in patients with transfusion dependent thalassemia: an insight on response to deferasirox, Muhammad Shariq Shaikh and Salman Naseem Adil

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Aleukemic myeloid sarcoma of the breast, Muhammad Shariq Shaikh and Naila Kayani

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Hospital preparedness in community measles outbreaks-challenges and recommendations for low-resource settings, Sadia Shakoor, Fatima Mir, Anita Zaidi, and Afia Zafar

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High rate of non-susceptibility to metronidazole and clindamycin in anaerobic isolates: data from a clinical laboratory from Karachi, Pakistan, Sadia Omer Sheikh, Kauser Jabeen, Saba Qaiser, Syed Tanwir Ahsan, Erum Khan, and Afia Zafar

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Spectrum of histopathological findings in postmenopausal bleeding, Muhammad Usman Tariq, Romana Idress, Ahmed Raheem, and Naila Kayani

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Cyclooxygenase-2 Polymorphisms and Breast Cancer associated risk in Pakistani patients, Moatter T, Aban M, Iqbal W, and Shahid Pervez

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Aspergillus fumigatus spinal abscess in an immunocompetent child, Mohammad Faizan Zahid and Joveria Farooqi

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Rhabdomyosarcoma--an Epidemiological and Histopathologic study of 277 cases from a major tertiary care center in Karachi, Pakistan, Ahmad Z, Din N. U, Ahmad A, Imran S, Shahid Pervez, Ahmed R, and Kayani N

Submissions from 2014

Distribution of EGFR mutations commonly observed in primary lung Adenocarcinomas in Pakistan as predictors for targeted therapy, Ahmed Z. A, Moatter T, Siddiqui A, and Shahid Pervez

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How our practice of Histopathology, especially Tumour pathology has changed in the last two decades: reflections from a major referral center in Pakistan, Zubair Ahmad, Romana Idress, Saira Fatima, Huma Arshad, Nasir Ud Din, Aisha Memon, Khurram Minhas, Arsalan Ahmed, Syeda Samia Fatima, Muhammad Arif, Rashida Ahmed, Saroona Haroon, Shahid Pervez, Sheema Hassan, and Naila Kayani

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Distribution of EGFR mutations commonly observed in primary Lung Adenocarcinomas in Pakistan as predictors for targeted therapy, Zeeshan Ansar Ahmed, Tariq Moatter, Areeba Siddiqui, and Shahid Pervez

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Tyrosine kinase inhibitors in cancer therapeutics: great expectations from small molecules, Zeeshan A Ansar and tariq moatter

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MP39-17 MECP2 Silencing in high grade bladder Cancer derived HTB-5 Cell line affects Cellular Proliferation and Migratory ability, Shumaila Bilgrami, Zulfiqar Naqvi, Khalid Shaikh, El-Nasir Lalani, and Farhat Abbas

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Chondroblastoma: a clinico-pathological analysis, Nasir-Ud Din

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Human ophthalmomyiasis externa caused by the sheep botfly oestrus ovis: a case report from Karachi, Pakistan, Naima Fasih, Kanza Noor Qaiser, Syeda Aisha Bokhari, Bushra Jamil, and Mohammad Asim Beg

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Shifting of vitamin D deficiency to hypervitaminosis and toxicity, Aysha Habib, Hafsa Majid, and Romaina Iqbal

Chondromyxoid Fibroma; experience of 36 cases of an intriguing entity, Saroona Haroon, Nasir Uddin, Shahid Pervez, Naila Kayani, Rashida Ahmed, Kamran Hafeez, and Masood Umer