Efficacy and safety of ab interno trabeculectomy in juvenile open-angle glaucoma
Document Type
Article
Department
Ophthalmology
Abstract
Objective: To determine the efficacy and safety of ab interno trabeculectomy with Trabectome in juvenile open-angle glaucoma (JOAG) patients.
Design: Prospective cohort study.
Methods: Evaluation of the 12-month results of 2 patient groups receiving ab interno trabeculectomy: group 1, eyes with no prior incisional surgery; group 2, eyes that had prior incisional cataract or glaucoma surgery.
Results: Group 1, 40 eyes (average age 31 ± 7 years), had a significant reduction in intraocular pressure (IOP) of 10.6 mm Hg at 12 months from a baseline of 27.4 mm Hg (p = 0.01), and the number of glaucoma medications reduced by 0.4 (p = 0.80). Four eyes (10%) within the study period required a secondary glaucoma surgery. Group 2, 20 eyes (average age 27 ± 8 years), had a significant reduction in IOP of 8.8 mm Hg from a baseline of 27.1 mm Hg (p = 0.06), and the number of glaucoma medications reduced by 1.4 (p = 0.36). Five eyes (25%) from this group underwent a secondary glaucoma surgery within 12 months.
Conclusion: After 1 year of follow-up, ab interno trabeculectomy appears to be an effective and safe intervention for patients with JOAG; however, a reduction in use of topical medications may not be observed in those receiving ab interno trabeculectomy as a primary procedure.
Publication (Name of Journal)
Canadian Journal of Ophthalmology
Recommended Citation
Arora, S.,
Maeda, M.,
Francis, B.,
Maeda, M.,
Sit, A. J.,
Mosaed, S.,
Nazarali, S.,
Damji, K. F.
(2018). Efficacy and safety of ab interno trabeculectomy in juvenile open-angle glaucoma. Canadian Journal of Ophthalmology, 53(5), 482-486.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_ophthalmol/31
Comments
This work was published before the author joined Aga Khan University.