Document Type
Report
Department
Pulmonary and Critical Care
Abstract
Extramedullaryplasmacytoma (EMP) represents a peculiar and typically progressive malignancy that can originate outside the bone marrow. Primary pulmonary plasmacytoma (PPP) is a rare subset of EMP, confined to the lung. A 55-year-old man, diabetic, non-smoker presented to our clinic with a right chest wall swelling. A routine chest radiograph showed a well-circumscribed opacity in the right upper lung zone. A CT of the chest revealed a large right upper lobe mass with extensive local infiltration. Biopsy and immunohistochemical evaluation led to a diagnosis of PPP. Screening for multiple myeloma was negative. Serum immunofixation showed an IgG lambda monoclonal gammopathy, found in a minority of PPP patients. In view of disease extent, treatment with chemotherapy and radiotherapy was initiated. The patient is currently in out patient follow-up and has shown a favourable response to the treatment with a considerable decrease in serum IgG levels.
Publication (Name of Journal)
BMJ case reports.
Recommended Citation
Rahim, Y.,
Tareen, F. Z.,
Ahmed, R.,
Khan, J.
(2019). Primary pulmonary plasmacytoma presenting with rare IgG lambda monoclonal gammopathy. BMJ case reports., 12(3), e227514..
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_med_pulm_critcare/146
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