To characterize features of acute myocardial infarction (AMI) in a Pakistani population, and assess the role of thrombolysis in our country, we studied 194 consecutive admitted patients with enzyme positive AMI. Males were affected three times more frequently; women, although affected less, had a higher incidence of complications than men. Premature coronary artery disease (CAD) was present in 50% patients presenting with AMI. An unusually high incidence of anterior wall myocardial infarction (39%) was seen. Complications were frequent with a predominance of LV failure symptoms. Cardiogenic shock was associated with a very high mortality, in excess of 93%. Streptokinase (SK) was administered in 60% patients with suspected transmural AMI. A statistically significant reduction in mortality was seen in the group that received SK (15.2%) compared to those who did not receive SK (24.7%), (p = < 0.05).
JPMA. The Journal of the Pakistan Medical Association
Karim, M. A.,
(1995). Thrombolytic therapy in acute myocardial infarction in Pakistan.. JPMA. The Journal of the Pakistan Medical Association, 45(3), 54-58.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_med_med/568
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