An assessment of mantoux test in the diagnosis of tuberculosis in a BCG-vaccinated, tuberculosis-endemic area
Medicine; Pathology and Microbiology
Outpatient clinics at a tertiary care referral center where Mantoux test was done as part of pre-employment medical examination and work-up of suspected tuberculosis. Objective: To assess the utility of Mantoux test in the diagnosis of active tuberculosis, in a BCG-vaccinated, TB endemic area. Design: A prospective, case-control study, conducted over a period of two years. For statistical analysis, patients with active tuberculosis were categorized on the basis of disease site and confirmatory tests. Results: The size of induration on Mantoux test was significantly different between patients with active TB and healthy individuals (p5 mm induration; test specificity increased with increasing size of induration and was highest (86%) with induration of >15 mm for both pulmonary and extrapulmonary TB. ESR was also significantly higher (p< 0.05) in TB patients. Older patients without active TB were observed to have higher ESR and larger induration on MT. Conclusions: Mantoux test, with or without ESR, provides useful supportive evidence of active TB in patients with pulmonary and extrapulmonary TB in our population.
Publication ( Name of Journal)
Infectious Diseases Journal of Pakistan
(2008). An assessment of mantoux test in the diagnosis of tuberculosis in a BCG-vaccinated, tuberculosis-endemic area. Infectious Diseases Journal of Pakistan, 17(1), 18-22.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_med_med/494