Clinical factors associated with mortality in dengue infection at a tertiary care center
Document Type
Article
Department
Medicine
Abstract
We conducted a cross-sectional study to investigate the clinical factors associated with mortality in Patients with dengue viral infection at a tertiary care center over a 3 year period. Six hundred ninety-nine Patients with a clinical diagnosis of dengue fever (DF), dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS) during the study period were included in the study. Data were collected with a predesigned form comprised of demographics, duration of fever, associated symptoms, diagnosis of DF, DHF and DSS, and laboratory parameters [complete blood count, coagulation tests, creatinine, serum glutamic pyruvic transaminase (SGPT)], dengue IgM was checked in all Patients by ELISA Outcomes (survival/mortality) and complications were recorded. Mortality was the primaryoutcome measure. DF constituted 86 4% (604), DHF constituted 11.6% (81) and DSS constituted 2% (14) of Patients. The mortality rate was 2 7% (19). The mean white blood cell count in those who died was 13 3, in those who survived was 5.3, the difference was significant (p=0 02) The mean BUN in those who died was 33 2, those who survived was 13.8, (p=0.007). The mean bicarbonate level in those who died was 17 1, those who survived was 185 (p 300 mg/dl, bleeding, an altered mental status and shock at presentation were all significantly associated with mortality in Patients with dengue virus infection (p=0 008, p001, p001, p001, respectively)
Publication (Name of Journal)
Southeast Asian Journal of Tropical Medicine and Public Health
Recommended Citation
Almas, A.,
Parkash, O.,
Akhter, J.
(2010). Clinical factors associated with mortality in dengue infection at a tertiary care center. Southeast Asian Journal of Tropical Medicine and Public Health, 41(2), 333-340.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_med_med/17