The potential role of persister cells in urinary tract infections
Document Type
Article
Department
Internal Medicine
Abstract
Purpose of review: This review explores the role of persister cells in urinary tract infections (UTIs). UTIs are one of the most common bacterial infections, affecting millions of people worldwide. Persister cells are a subpopulation of bacteria with dormant metabolic activity which allows survival in the presence of antibiotics.
Recent findings: This review summarizes recent research on the pathogenesis of persister cell formation in UTIs, the impact of persister cells on the effectiveness of antibiotics, the challenges they pose for treatment, and the need for new strategies to target these cells. Furthermore, this review examines the current state of research on the identification and characterization of persister cells in UTIs, as well as the future directions for investigations in this field. This review highlights the importance of understanding the role of persister cells in UTIs and the potential impact of targeting these cells in the development of new treatments.
Publication (Name of Journal)
Current urology reports
DOI
https://doi.org/10.1007/s11934-023-01182-5
Recommended Citation
Durrani, B.,
Mohammad, A.,
Ljubetic, B. M.,
Dobberfuhl, A. D.
(2023). The potential role of persister cells in urinary tract infections. Current urology reports, 24(11), 541-551.
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_med_intern_med/242