Bilateral congenital cryptorchidism and unilateral Leydig cell tumor in an adult presenting with gynecomastia and primary infertility: A case report

Authors

Mirza Rameez Samar, Aga Khan University
Saqib Raza Khan, Aga Khan UniversityFollow
Muhammad Tariq, Lady Reading Hospital, Peshawar, Pakistan
Salman Muhammad Soomar, Aga Khan University
Mehwish Shahzadi, Aga Khan University

Document Type

Article

Department

Haematology/Oncology

Abstract

Introduction and importance: The neoplasms of the testis are sporadic tumors among men. Furthermore, the rarest subset of these is neoplasms belonging to the stromal tumors of the sex cord. Leydig cell tumors are the most common form among the testicular stromal tumors. In our case, the underlying risk factor associated with the development of Leydig cell tumors was cryptorchidism. While mostly unilateral, cases of bilateral cryptorchidism may be present and have been rarely reported.
Case presentation: We report a 36-year-old gentleman who presented to us with the inability to carry off intercourse without difficulty attaining erection on stimulation for the past two years. He had a history of left undescended testis since birth, for which he underwent left orchidopexy 20 years ago. An ultrasound of the pelvis showed an oval hypoechoic-shaped heterogeneous mass in the right mid-inguinal canal. Relevant blood investigations showed a deranged hormonal profile. He then underwent an uneventful right radical orchiectomy, histopathology of which was consistent with Leydig cell tumor.
Clinical discussion: CT with a history of bilateral cryptorchidism has rarely been reported. This case highlights its clinical presentation, management, and further follow-up in such patients.
Conclusion: Bilateral congenital cryptorchidism may be associated with Leydig cell tumor years later in life hence long-term follow-up is required for these patients. The clinical presentation of these tumors may vary among individuals. Any change in physical appearance, hormonal assay, and imaging studies should promptly be followed for possible surgical resection and close monitoring

Comments

Issue, and pagination are not provided by the author/publisher

Publication (Name of Journal)

International journal of surgery case reports

Recommended Citation

Samar, M. R., Khan, S. R., Tariq, M., Soomar, S. M., Shahzadi, M. (2022). Bilateral congenital cryptorchidism and unilateral Leydig cell tumor in an adult presenting with gynecomastia and primary infertility: A case report. International journal of surgery case reports, 93.
Available at: https://ecommons.aku.edu/pakistan_fhs_mc_med_haematol_oncol/79