Absence of the Y chromosome in patients with chronic granulocytic leukaemia
The Y chromosome was missing from the cells of aspirated bone marrow in 2 patients with chronic granulocytic leukaemia (CGL). In both cases, blast cell transformation occurred within 17 months of presentation. Their short course is in contrast to the hypothesis that absence of the Y chromosome in CGL is compatible with long survival.
(1975). Absence of the Y chromosome in patients with chronic granulocytic leukaemia. Acta Haematologica, 54, 350-357.
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