Title

Absence of the Y chromosome in patients with chronic granulocytic leukaemia

Document Type

Article

Department

Haematology/Oncology

Abstract

The Y chromosome was missing from the cells of aspirated bone marrow in 2 patients with chronic granulocytic leukaemia (CGL). In both cases, blast cell transformation occurred within 17 months of presentation. Their short course is in contrast to the hypothesis that absence of the Y chromosome in CGL is compatible with long survival.

Publication

Acta Haematologica