Treating chronic hepatitis delta: The need for surrogate markers of treatment efficacy
Document Type
Article
Department
Gastroenterology
Abstract
Chronic hepatitis delta represents the most severe form of chronic viral hepatitis. The current treatment of hepatitis delta virus (HDV) infection consists of the use of interferons and is largely unsatisfactory. Several new compounds are currently in development for the treatment of HDV infection. However, surrogate markers that can be used to develop clinical endpoints in HDV infection are not well defined. In the current manuscript, we aimed to evaluate the existing data on treatment of HDV infection and to suggest treatment goals (possible "trial endpoints") that could be used across different clinical trials.
Publication (Name of Journal)
Journal of hepatology.
Recommended Citation
Yurdaydin, C.,
Abbas, Z.,
Buti, M.,
Cornberg, M.,
Esteban, R.,
Etzion, O.,
Gane, E. J.,
Gish, R. G.,
Hamid, S.,
Heller, T.
(2019). Treating chronic hepatitis delta: The need for surrogate markers of treatment efficacy. Journal of hepatology., 70(5).
Available at:
https://ecommons.aku.edu/pakistan_fhs_mc_med_gastroenterol/258
Comments
Clinical Trial Watch
Pagination not provided by Author/publisher.